Human ABCE1 cannot functionally replace its yeast ortholog. Yeast–human chimera analysis identified NBD1 as a major interspecies barrier. Genetic screening yielded hABCE1 revertants that rescue yeast viability but fail to suppress aberrant translation reinitiation in the 3′ UTR.
Eriko Nakata +3 more
wiley +1 more source
Implications of Intermittent Fasting on Placental Function [PDF]
Introduction: Women who partake in Ramadan during pregnancy have lower placental weights. Intermittent fasting (IF) impacts upon asynchronous dietary cues and the entrained sleep cycle.
Sansby, Luke
core +1 more source
The Role of Branched-Chain Amino Acids in Nutrient Allocation of the Porcine Placenta: A Review. [PDF]
Bai J +9 more
europepmc +1 more source
Na plus-facilitated reactions of neutral amino acids with a cationic amino acid transport system.
H. Christensen +2 more
semanticscholar +1 more source
Recent insights into the molecular mechanism of ubiquinol oxidation by cytochrome bc1
The review reflects on the mechanism of the catalytic reaction in cytochrome bc1: the electron bifurcation that involves the separation of two electrons derived from the quinol oxidation to opposite sides of the enzyme across the membrane. This review summarizes the long‐standing effort to understand the mechanism of quinol oxidation catalyzed by ...
Anna Wójcik‐Augustyn +2 more
wiley +1 more source
Orchestrating Physiological Homeostasis: The Spatial and Cellular Heterogeneity of Tryptophan Transport and Metabolism. [PDF]
Zhu X +5 more
europepmc +1 more source
Selective elimination of quiescent cancer cells by dequalinium chloride via ROS‐mediated ferroptosis
Dequalinium chloride (DQ) selectively eliminates quiescent cancer cells (QCCs) by amplifying mitochondrial ROS. QCCs exhibit elevated basal ROS and limited redox‐buffering capacity, making them vulnerable to further ROS increases. DQ‐induced ROS exceeds the tolerance threshold, triggering lipid peroxidation and ferroptosis, whereas proliferating cells ...
Kotaro Miyamoto +14 more
wiley +1 more source
Placental expression and activity of system A and system L amino acid transporters in pregnancies complicated by diabetes mellitus and fetal growth disorders: a systematic review. [PDF]
Ługowski F +3 more
europepmc +1 more source
A high‐affinity, tryptophan‐selective amino acid transport system in human macrophages
Robert L. Seymour +3 more
semanticscholar +1 more source
During the current opioid crisis, the majority of overdose deaths are attributed to ultra‐potent synthetic opioids, such as fentanyl. While fentanyl exerts its action via opioid receptors, we propose that potassium channels in the brain blood vessels may also sense fentanyl.
Shiwani Thapa +4 more
wiley +1 more source

