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Evaluation of the Effects of the Sodium-Glucose Cotransporter 2 Inhibitors and Sacubitril/Valsartan Combined Therapy in Patients with HFrEF: An Echocardiographic Study. [PDF]
Int J Mol SciFumarulo I +11 more
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4-Aminobutyric acid methyl ester hydrochloride, a precursor of 4-aminobutyric acid
Biochemical Pharmacology, 19834-Aminobutyric methyl ester hydrochloride (GME) is able to cross the blood-brain barrier after intracardiac administration to the rat. GME has an LD50 of 1300 mg/kg in mice and 950 mg/kg in rats, exhibits an antiaggressive effect and is able to decrease isoniazid-induced convulsions in the rat.
M, Bianchi +4 more
openaire +2 more sources
2016
Gamma-aminobutyric acid (GABA) is a small (molecular weight: 103 g/mol) zwitterionic nonprotein amino acid (Roberts and Frankel 1950) that can be found in all prokaryotic and eukaryotic organisms including plants. It is the main inhibitory neurotransmitter in the mammalian brain but has many distinct roles within different tissues in an organism.
Vlainić, Josipa +1 more
openaire +1 more source
Gamma-aminobutyric acid (GABA) is a small (molecular weight: 103 g/mol) zwitterionic nonprotein amino acid (Roberts and Frankel 1950) that can be found in all prokaryotic and eukaryotic organisms including plants. It is the main inhibitory neurotransmitter in the mammalian brain but has many distinct roles within different tissues in an organism.
Vlainić, Josipa +1 more
openaire +1 more source
Journal of Neurochemistry, 1968
Abstract—A systematic study was made of aminobutyrate transaminase (4‐aminobutyrate: 2‐oxoglutarate aminotransferase, I.U.B.2.6.1.19) in the developing rat brain. Assays of enzymic activity were made in whole brain of seven to twenty‐one animals at each day of age from birth to day 30. The numerous analyses allowed statistical treatment and recognition
K. L. Sims +3 more
openaire +1 more source
Abstract—A systematic study was made of aminobutyrate transaminase (4‐aminobutyrate: 2‐oxoglutarate aminotransferase, I.U.B.2.6.1.19) in the developing rat brain. Assays of enzymic activity were made in whole brain of seven to twenty‐one animals at each day of age from birth to day 30. The numerous analyses allowed statistical treatment and recognition
K. L. Sims +3 more
openaire +1 more source
British journal of pharmacology, 1973
1. Rat retinae pre-incubated and incubated at 37 degrees C in media containing amino-oxyacetic acid (AOAA) (0.1 muM to 1 mM) accumulated more (3)H-gamma-aminobutyric acid ((3)H-GABA) than control retinae incubated in the absence of AOAA. This increased accumulation of (3)H-GABA by tissue exposed to AOAA was not apparent at short incubation times (0-20 ...
M J, Neal, M S, Starr
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1. Rat retinae pre-incubated and incubated at 37 degrees C in media containing amino-oxyacetic acid (AOAA) (0.1 muM to 1 mM) accumulated more (3)H-gamma-aminobutyric acid ((3)H-GABA) than control retinae incubated in the absence of AOAA. This increased accumulation of (3)H-GABA by tissue exposed to AOAA was not apparent at short incubation times (0-20 ...
M J, Neal, M S, Starr
openaire +2 more sources
The metabolic roles of free amino acids during seed development.
Plant Science, 2018Amino acids play vital roles in the central metabolism of seeds. They are primarily utilized for the synthesis of seed-storage proteins, but also serve as precursors for the biosynthesis of secondary metabolites and as a source of energy.
R. Amir, G. Galili, Hagai Cohen
semanticscholar +1 more source
Gamma-Aminobutyric Acid and the Liver
Digestive Diseases, 2008Gamma-aminobutyric acid (GABA) is a potent amino acid neurotransmitter with various physiologic effects throughout the body. Over the past 40 years it has become evident that the mammalian liver contains high concentrations of GABA which are carefully regulated by a series of hepatic metabolic pathways and a specific sodium-dependent active transport ...
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Food Chemistry, 2019
Although refrigeration is commonly used in the storage of 'Nanguo' pears (Pyrus ussuriensis Maxim.), long-term refrigeration can result in browning of the pericarp. In this study, we aimed to determine how γ-aminobutyrate (GABA) affects the mitochondrial
Jiaxin Li +5 more
semanticscholar +1 more source
Although refrigeration is commonly used in the storage of 'Nanguo' pears (Pyrus ussuriensis Maxim.), long-term refrigeration can result in browning of the pericarp. In this study, we aimed to determine how γ-aminobutyrate (GABA) affects the mitochondrial
Jiaxin Li +5 more
semanticscholar +1 more source
International Journal of Chemical Kinetics, 1992
AbstractWe studied the kinetics of the N‐chlorination of 2‐aminobutyric, 3‐aminoisobutyric, and 4‐aminobutyric acids by sodium hypoclorite in strongly alkaline aqueous solution. As in the case of other amines, the rate of formation of the four N‐chloroamino acids was proportional to the concentrations of hypochlorite and amino acid, and inversely ...
J. M. Antelo +2 more
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AbstractWe studied the kinetics of the N‐chlorination of 2‐aminobutyric, 3‐aminoisobutyric, and 4‐aminobutyric acids by sodium hypoclorite in strongly alkaline aqueous solution. As in the case of other amines, the rate of formation of the four N‐chloroamino acids was proportional to the concentrations of hypochlorite and amino acid, and inversely ...
J. M. Antelo +2 more
openaire +2 more sources
Enhancement of NGF- and cholera toxin-induced neurite outgrowth by butyrate in PC12 cells.
Brain Research, 2002Yuka Suzuki-Mizushima +4 more
semanticscholar +1 more source