A half century of γ-aminobutyric acid [PDF]
γ-aminobutyric acid has become one of the most widely known neurotransmitter molecules in the brain over the last 50 years, recognised for its pivotal role in inhibiting neural excitability. It emerged from studies of crustacean muscle and neurons before its significance to the mammalian nervous system was appreciated.
Smart, TG, Stephenson, FA
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There has been a controversy as to whether exogenous γ-aminobutyric acid can enter brain regions. The concept of "microbe-gut-brain axis" suggestes that exogenous γ-aminobutyric acid is able to enter the body through oral administration.
Wei HE+5 more
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Mechanisms for Simultaneous Removal of Formaldehyde and Glyoxal by Amino Acids and Cytotoxicity of Their Products [PDF]
This study aimed to investigate the mechanisms by which amino acids simultaneously remove formaldehyde and glyoxal and to evaluate the cytotoxicity of their products.
LIN Jiayu, HUANG Caihuan, ZHENG Jie, LIU Fu, OU Juanying, ZHOU Hua, HU Jiaman, OU Shiyi
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Background and objective: Production of γ-aminobutyric acid has recently much interested because of its benefits for health. The objective of this study was to optimize γ-aminobutyric acid production by a novel identified Lactiplantibacillus pentosus ...
Thi-Bich-Thuy Do+2 more
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Characterising the role of GABA and its metabolism in the wheat pathogen Stagonospora nodorum. [PDF]
A reverse genetics approach was used to investigate the role of γ-aminobutyric acid metabolism in the wheat pathogenic fungus Stagonospora nodorum. The creation of mutants lacking Sdh1, the gene encoding succinic semialdehyde dehydrogenase, resulted in ...
Oliver Mead+3 more
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The Effect of Spraying Salicylic Acid and Beta-Aminobutyric Acid on Physiological and Biochemical Characteristics and Yield of Dracocephalum moldavica (L.) [PDF]
In order to investigate the effects of foliar spraying of salicylic acid and beta-aminobutyric acid on yield, physiological and biochemical characteristics of Dracocephalum moldavica (L.), during cropping year of 2017-2018, in a experiment based on a ...
Fatemeh Mahsa Karamoozian+3 more
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The preparative synthetic approach to α,α-difluoro-γ-aminobutyric acid
Aim. To develop a convenient synthetic approach for the preparation of multigram amounts of 2,2-difluoro-γ-aminobutyric acid, which is pharmacologically promising analog of γ-aminobutyric acid (GABA). Results and discussion.
Maksym Ya. Bugera+3 more
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Background Exogenous application of gamma-aminobutyric acid (GABA) could relieve stress symptoms caused by abiotic stresses including anoxia, heat and cold shock, drought, and salt.
Faraj Hijaz, Nabil Killiny
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Involvement of sialic acid in the regulation of -aminobutyric acid uptake activity of -aminobutyric acid transporter 1 [PDF]
The γ-aminobutyric acid (GABA) transporters (GATs) have long been recognized for their key role in the uptake of neurotransmitters. The GAT1 belongs to the family of Na(+)- and Cl(-)-coupled transport proteins, which possess 12 putative transmembrane (TM) domains and three N-glycosylation sites on the extracellular loop between TM domains 3 and 4 ...
Jian Fei+3 more
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THE EFFECTS OF NO-711 AND ß-ALANINE ON GLUTAMATE AND γ -AMINOBUTYRIC ACID UPTAKE BY NERVE TERMINALS ISOLATED FROM RATS AFTER PERINATAL HYPOXIA [PDF]
The effects of highly-selective blocker of γ-aminobutyric acid transporters of GAT1, NO-711, and substrate inhibitor of γ aminobutyric acid transporters GAT3, ß-alanine on the initial velocity of L-[14C]glutamate and [3H]-γ-aminobutyric acid uptake by ...
Dudarenko M. V.+6 more
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