Results 111 to 120 of about 5,128,888 (403)
Acrylamide neurotoxicity on the cerebrum of weaning rats
Neural Regeneration Research, 2015 The mechanism underlying acrylamide-induced neurotoxicity remains controversial. Previous studies have focused on acrylamide-induced toxicity in adult rodents, but neurotoxicity in weaning rats has not been investigated.
Su-min Tian +5 more
doaj +1 more source
Alterations in gut microbiota and metabolites contribute to postoperative sleep disturbances
Animal Models and Experimental Medicine, EarlyView.In this study, we classified postoperative patients into poor sleepers (PS) and good sleepers (GS) based on the bispectral index (BIS), and transplanted their fecal microbiota to pseudo‐germ‐free rats to analyze the sleep changes in rats and the potential mechanism.
Hui Zhong +7 more
wiley +1 more source
Homotaurine, a safe blood-brain barrier permeable GABAA-R-specific agonist, ameliorates disease in mouse models of multiple sclerosis. [PDF]
, 2018 There is a need for treatments that can safely promote regulatory lymphocyte responses. T cells express GABA receptors (GABAA-Rs) and GABA administration can inhibit Th1-mediated processes such as type 1 diabetes and rheumatoid arthritis in mouse models.
Dang, Hoa +4 more
core +3 more sources
PLoS ONE, 2014 The non-protein amino acid β-aminobutyric acid (BABA) can induce plant resistance to a broad spectrum of biotic and abiotic stresses. However, BABA-induced plant resistance to insects is less well-studied, especially its underlying mechanism.
He-He Cao +7 more
doaj +1 more source
Animal Models and Experimental Medicine, EarlyView.The electrophysiological change in neurons might contribute to the cognitive and emotional changes during pregnancy. Abstract Background Pregnancy affects learning and memory in women. Thus, to investigate the effects of pregnancy, the authors examined the brain electrophysiology of pregnant mice.
Xuefan Bin, Huijuan Luo
wiley +1 more source
Journal of Separation Science, Volume 45, Issue 24, Page 4416-4426, December 2022., 2022 This work proposes a comprehensive two‐dimensional gas chromatography method for the resolution and quantification of 27 amino acids, including 17 enantiomeric pairs, as stable N‐trifluoroacetyl‐O‐methyl ester derivatives. The derivatization approach in combination with enantioselective two‐dimensional gas chromatography has proven to be highly ...
Raphaël Pepino +4 more
wiley +1 more source
ANXIETY IN MAJOR DEPRESSION AND CEREBROSPINAL FLUID FREE GAMMA‐AMINOBUTYRIC ACID
Depression and Anxiety, 2014 Low gamma‐aminobutyric acid (GABA) is implicated in both anxiety and depression pathophysiology. They are often comorbid, but most clinical studies have not examined these relationships separately. We investigated the relationship of cerebrospinal fluid (
J. Mann +9 more
semanticscholar +1 more source
How transcranial direct current stimulation facilitates post-stroke rehabilitation [PDF]
arXiv, 2019 Whether transcranial direct current stimulation (tDCS) benefits stroke rehabilitation remains unclear. To investigate how tDCS reorganizes brain circuitry, nineteen post-stroke patients underwent rehabilitation sessions with bi-hemispheric real vs sham tDCS intervention. Resting motor threshold measurements showed tDCS evoked higher excitability in the
arxiv
Midazolam: an essential palliative care drug
Palliative Care and Social Practice, 2020 Midazolam is a commonly used benzodiazepine in palliative care and is considered one of the four essential drugs needed for the promotion of quality care in dying patients.
Eric Prommer
doaj +1 more source
Photo‐controlled Release of Urea Enables the Detection of Urea‐Urease Intermediates by cryo‐FTIR
Angewandte Chemie International Edition, Accepted Article.Caged compounds are a valuable tool to photocontrol the release of enzymatic substrates in a reaction. For example, caged urea molecules were proposed to control urea delivery to urease reactions and aid the determination of the catalytic mechanism of this enzyme.
Caterina Netto +7 more
wiley +1 more source