Results 251 to 260 of about 5,282,507 (400)

Selective γ-Aminobutyric Acid Type A Receptor Antagonism Reverses Isoflurane Ischemic Neuroprotection [PDF]

, 2006
Hazem E. Elsersy, Javier Mixco, Huaxin Sheng, Robert D. Pearlstein, David S. Warner   +4 more
openalex   +1 more source

Novel approaches for drug development against chronic primary pain: A systematic review

British Journal of Pharmacology, EarlyView.
Abstract Chronic primary pain (CPP) persisting for more than 3 months, associated with significant emotional distress without any known underlying cause, is an unmet medical need. Traditional or adjuvant analgesics do not provide satisfactory pain relief for a great proportion of these patients.
Valéria Tékus, Éva Borbély, Andreas Goebel, Ralf Baron, Zsófia Hajna, Zsuzsanna Helyes   +5 more
wiley   +1 more source

Perfluorooctanesulfonic acid (PFOS) antagonizes gamma-aminobutyric acid (GABA) receptors in larval zebrafish and mammalian models. [PDF]

Toxicol Sci
Owen R, de Macedo G, Nerlich J, Scharkin I, Bartmann K, Döbler J, Engelmann B, Rolle-Kampczyk UE, Leuthold D, Gutsfeld S, Schweiger N, Tal T.   +11 more
europepmc   +1 more source

Investigating Gut Microbiota with Gamma- Aminobutyric Acid Production Potential in Methamphetamine Addiction Recovery [PDF]

Siti Khadijah Kiraman, Hijaz Ridzwan, Nasim Arshad, Tengku Mohd Saifuddin Tengku Kamarul Bahri, Peng Ye, Hein M. Tun, Seok Fang Oon, Hajar Fauzan Ahmad   +7 more
openalex   +1 more source

Gama-aminobutyric acid accumulation in Elsholtzia splendens in response to copper toxicity [PDF]

, 2005
Xiaoe Yang, Hongyun Peng, Shengke Tian
openalex   +1 more source

Evaluation of preclinical antipsychotic models used to support first‐in‐human clinical trials

British Journal of Pharmacology, EarlyView.
Abstract Schizophrenia is regarded as a complex and heterogeneous psychiatric disorder, characterised by diverse symptoms and comorbidities, which complicate both clinical management and drug development. Current pharmacological treatment, primarily based on dopamine D2 receptor antagonism or partial agonism, which has not markedly progressed since the
Thi Viet Ha Nguyen, Declan P. McKernan, John P. Kelly   +2 more
wiley   +1 more source

The beneficial effect of gamma aminobutyric acid on diabetic nephropathy in type 2 diabetic rat model and their offspring. [PDF]

Res Pharm Sci
Rezazadeh H, Maghareh-Dehkordi S, Touliat MV, Talebi A, Soltani N.   +4 more
europepmc   +1 more source

Impact of frequency drift on gamma‐aminobutyric acid‐edited MR spectroscopy

Magnetic Resonance in Medicine, 2014
Ashley D. Harris, Ashley D. Harris, B. Glaubitz, J. Near, C. J. Evans, N. Puts, N. Puts, T. Schmidt-Wilcke, M. Tegenthoff, P. B. Barker, P. B. Barker, R. Edden, R. Edden   +12 more
semanticscholar   +1 more source

Subunit composition of glutamate and gamma-aminobutyric acid receptors in status epilepticus

, 2014
Tobias Loddenkemper, Delia M. Talos, Ryan T. Cleary, Annelise Joseph, Iván Sánchez Fernández, Andreas V. Alexopoulos, Prakash Kotagal, Imad Najm, Frances E. Jensen   +8 more
openalex   +2 more sources

Epigenetic mechanisms and therapeutic innovations in chronic pain‐associated neuropsychiatric co‐morbidities

British Journal of Pharmacology, EarlyView.
Abstract Chronic pain, marked by nociceptive sensitization and maladaptive neuroplasticity, affects 30% of the global population with escalating socioeconomic burdens. Epidemiological data show a 2‐3‐fold increase in neuropsychiatric co‐morbidities among individuals with chronic pain, where epigenetic dysregulation serves as a key mechanism linking ...
Kai Zhang, Sijia Zhu, Na Xing, Zhen Zhou, Jiayi Chen, Tianen Si, Mingrui Li, Lin Jia, Yousef Rastegar‐Kashkooli, Tom J. Wang, Wei Zhu, Jing Li, Chao Jiang, Junmin Wang, Moxin Wu, Xiaoping Yin, Weidong Zang, Jian Wang, Songxue Su   +18 more
wiley   +1 more source