Results 41 to 50 of about 5,282,507 (400)
Response of γ-Aminobutyric Acid Metabolic Pathway in Tea Plants to Early Infestation of Ectropis obliqua [PDF]
Chaye kexueTea geometrid (Ectropis obliqua Prout) infestation induces tea plants to release massive amounts of volatile organic compounds (VOCs), which are widely reported as important chemical cues that either repel the pests or attract their enemies. However, the
SUN Juan, CHEN Hui, LIU Guanhua, ZHANG Han, HUANG Fuyin, WANG Yuxi, WANG Nuo, BAO Demeng, SHI Jiang, DAI Weidong, CHEN Jian, FU Jianyu
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Modulation of the GABAergic pathway for the treatment of fragile X syndrome. [PDF]
, 2014 Fragile X syndrome (FXS) is the most common genetic cause of intellectual disability and the most common single-gene cause of autism. It is caused by mutations on the fragile X mental retardation gene (FMR1) and lack of fragile X mental retardation ...
Hagerman, Randi J +2 more
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Robust photoregulation of GABA(A) receptors by allosteric modulation with a propofol analogue. [PDF]
, 2012 Photochemical switches represent a powerful method for improving pharmacological therapies and controlling cellular physiology. Here we report the photoregulation of GABA(A) receptors (GABA(A)Rs) by a derivative of propofol (2,6-diisopropylphenol), a ...
Bruzik, Karol S +8 more
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Gamma-aminobutyric acid as a potential postbiotic mediator in the gut–brain axis
npj Science of FoodGamma-aminobutyric acid (GABA) plays a crucial role in the central nervous system as an inhibitory neurotransmitter. Imbalances of this neurotransmitter are associated with neurological diseases, such as Alzheimer’s and Parkinson’s disease, and ...
Jason D. Braga +2 more
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FoodsPulsed light is an emerging technique in plant physiology recognized for its ability to enhance germination and accumulate γ–aminobutyric acid in maize.
Liangchen Zhang +4 more
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Anterior cingulate gamma‐aminobutyric acid concentrations and electroconvulsive therapy
Brain and Behavior, 2020 Objective The anticonvulsant hypothesis posits that ECT’s mechanism of action is related to enhancement of endogenous anticonvulsant brain mechanisms. Results of prior studies investigating the role of the inhibitory neurotransmitter gamma‐aminobutyric ...
Vera J. Erchinger +14 more
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Scientific Reports, 2022 During an ischemic stroke, the brain releases various factors, including glutamate and γ-aminobutyric acid. Glutamate can cause neurotoxic effects through certain receptors and exacerbate neurological damage, while γ-aminobutyric acid as an inhibitory ...
Bo-hu Liu +3 more
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Combined therapy with GABA and proinsulin/alum acts synergistically to restore long-term normoglycemia by modulating T-cell autoimmunity and promoting β-cell replication in newly diabetic NOD mice. [PDF]
, 2014 Antigen-based therapies (ABTs) fail to restore normoglycemia in newly diabetic NOD mice, perhaps because too few β-cells remain by the time that ABT-induced regulatory responses arise and spread.
Chen, Zheying +4 more
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Moleculesγ-aminobutyric acid, a critical neurotransmitter, is experiencing an increasing demand in the medical and health fields. Conventional processes for γ-aminobutyric acid purification from fermentation broth encounter significant challenges, such as high ...
Yu Jing +5 more
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Molecular Genetics and Metabolism Reports, 2015 Methylenetetrahydrofolate reductase (MTHFR) is an enzyme key regulator in folate metabolism. Deficiencies in MTHFR result in increased levels of homocysteine, which leads to reduced levels of S-adenosylmethionine (SAM).
N.M. Jadavji +3 more
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