Results 61 to 70 of about 5,128,888 (403)

Insights into GABA receptor signalling in TM3 Leydig cells [PDF]

, 2005
gamma-Aminobutyric acid (GABA) is an emerging signalling molecule in endocrine organs, since it is produced by endocrine cells and acts via GABA(A) receptors in a paracrine/autocrine fashion.
Artur Mayerhofer, Behar TN, Ben Ari Y, Berman JA, Christof Geigerseder, Erdo SL, Frungieri MB, Fukura H, Gilon P, Haydar TF, Karl Föhr, Kriegstein AR, Lars Kunz, Lauder JM, Lee W, Leinekugel X, Malherbe P, Maric D, Mayerhofer A, Mayerhofer A, Mayerhofer A, Monica B. Frungieri, Owens DF, Owens DF, Ricardo S. Calandra, Richard F.G. Doepner, Ritta MN, Romi Raemsch, Silvia I. Gonzalez-Calvar   +28 more
core   +2 more sources

Decoding the dual role of autophagy in cancer through transcriptional and epigenetic regulation

FEBS Letters, EarlyView.
Transcriptional and epigenetic regulation controls autophagy, which exerts context‐dependent effects on cancer: Autophagy suppresses tumorigenesis by maintaining cellular homeostasis or promotes tumor progression by supporting survival under stress. In this “In a Nutshell” article, we explore the intricate mechanisms of the dual function of autophagy ...
Young Suk Yu, Ik Soo Kim, Sung Hee Baek
wiley   +1 more source

Homozygosity for a missense mutation in the 67 kDa isoform of glutamate decarboxylase in a family with autosomal recessive spastic cerebral palsy: parallels with Stiff-Person Syndrome and other movement disorders [PDF]

, 2004
Background Cerebral palsy (CP) is an heterogeneous group of neurological disorders of movement and/or posture, with an estimated incidence of 1 in 1000 live births.
A Lernmark, Alex F Markham, B Hagberg, BG Condie, C Geoffrey Woods, CL Fawer, Clare N Lynex, CM Wiles, David T Bonthon, DF Bu, DF Bu, DJ Stone, DL Martin, DL Martin, DP McHale, DP McHale, E Maestrini, Eamonn R Maher, F Sandbrink, G Gaffney, GE Homanics, H Asada, H Mitoma, HM Meinck, I Hughes, Ian M Carr, J Kim, J Volpe, Jack P Leek, JO Forfar, JS Lappalainen, K Burk, K Dinkel, KCK Kuban, KH Gustavson, LM Dubowitz, LM Levy, M Baraitser, M Solimena, M Solimena, MC Dalakas, MG Erlander, MH Butler, N Laprade, N Paneth, POD Pharoah, PS Eicher, PT Bosma, Rajgopal Achuthan, RW Bond, S Bundey, S Chattopadhyay, S Kono, S Kure, S Mitchell, SD Chessler, Simon Mitchell, V Cormier-Daire   +57 more
core   +2 more sources

Autophagy in cancer and protein conformational disorders

FEBS Letters, EarlyView.
Autophagy plays a crucial role in numerous biological processes, including protein and organelle quality control, development, immunity, and metabolism. Hence, dysregulation or mutations in autophagy‐related genes have been implicated in a wide range of human diseases.
Sergio Attanasio
wiley   +1 more source

Characterization of biodegradable food packaging films prepared with polyamide 4: Influence of molecular weight and environmental humidity

Food Bioengineering, Volume 1, Issue 3-4, Page 276-288, December 2022., 2022
Colorless and translucent polyamide 4 (PA4) films, which are both bio‐based and biodegradable, were prepared by the solution casting method in a dual‐solvent system. The physical properties of single PA4 films were originally characterized, and the effects of molecular weight and environmental humidity on PA4 were investigated. Abstract The development
Di Zhang, Rong Nie, Chunyue Zhang, Yibing Wang, Li Wang, Tao Chen, Liming Zhao   +6 more
wiley   +1 more source

Presynaptic actions of 4-Aminopyridine and γ-aminobutyric acid on rat sympathetic ganglia in vitro [PDF]

, 1980
Responses to bath-applications of 4-aminopyridine (4-AP) and -aminobutyric acid (GABA) were recorded intracellularly from neurones in the rat isolated superior cervical ganglion.
A Nistri, A Tokunaga, B Hue, B Katz, C Nicholson, CL Schauf, DA Brown, DA Brown, DA Brown, DA Brown, DA McAfee, DI Wallis, E Jankowska, E Kato, E Kato, G. ten Bruggencate, H Lundh, H Lundh, H Meves, IG Marshall, JE Heuser, JZ Yeh, JZ Yeh, K Golenhofen, M Lemeignan, M Lemeignan, M. Galvan, NG Bowery, P. Grafe, PR Adams, R Llinás, SY Chiu, T Brismar, T Yanagisawa, W Ulbricht, WC Bowman, WW Douglas   +36 more
core   +1 more source

2-Aminobutyric acid modulates glutathione homeostasis in the myocardium

Scientific Reports, 2016
A previous report showed that the consumption of glutathione through oxidative stress activates the glutathione synthetic pathway, which is accompanied by production of ophthalmic acid from 2-aminobutyric acid (2-AB).
Y. Irino, R. Toh, M. Nagao, Takeshige Mori, Tomoyuki Honjo, M. Shinohara, Shigeyasu Tsuda, Hideto Nakajima, S. Satomi-Kobayashi, T. Shinke, Hidekazu Tanaka, T. Ishida, O. Miyata, K. Hirata   +13 more
semanticscholar   +1 more source

Plasma lipidomic and metabolomic profiles in high‐grade glioma patients before and after 72‐h presurgery water‐only fasting

Molecular Oncology, EarlyView.
Presurgery 72‐h fasting in GB patients leads to adaptations of plasma lipids and polar metabolites. Fasting reduces lysophosphatidylcholines and increases free fatty acids, shifts triglycerides toward long‐chain TGs and increases branched‐chain amino acids, alpha aminobutyric acid, and uric acid.
Iris Divé, Lisa Hahnefeld, Katharina J. Wenger, Donat Kögel, Joachim Steinbach, Gerd Geisslinger, Michael W. Ronellenfitsch, Irmgard Tegeder   +7 more
wiley   +1 more source

In-vivo Magnetic Resonance Imaging of GABA and Glutamate [PDF]

arXiv, 2020
Chemical Exchange Saturation Transfer (CEST) Magnetic Resonance Imaging (MRI) is a molecular imaging methodology capable of mapping brain metabolites with relatively high spatial resolution. Specificity is the main goal of such experiments; yet CEST is confounded by spectral overlap between different molecular species.
arxiv  

Homologous Hexapeptides [PDF]

, 1975
The N-hydr oxysuccinimide esters of N-tritylated tripeptides II-V were coupled with hydroacetates of tripeptide esters VII-IX to correspoding N-tritylated hexapeptide esters XV-XXL The saponification of so obtained compounds followed by detritylation ...
B. Katušin-Ražem, B. Šimunić, V . Škarić, Đ. Škarić   +3 more
core   +1 more source