Results 61 to 70 of about 5,172,296 (338)
Advanced Functional Materials, EarlyView.Oct4‐nanoscript, a biomimetic nanoparticle‐based artificial transcription factor, precisely regulates cellular rejuvenation by activating Oct4 target genes, restoring epigenetic marks, and reducing DNA damage. In a progeria model, it effectively rescued aging‐associated pathologies and extended lifespan.
Hongwon Kim +8 more
wiley +1 more source
Cloning, expression, and localization of a rat brain high-affinity glycine transporter [PDF]
, 1992 A cDNA clone encoding a glycine transporter has been isolated from rat brain by a combined PCR and plaque-hybridization strategy. mRNA synthesized from this clone (designated GLYT1) directs the expression of sodium-and chloride-dependent, high-affinity ...
Brecha, Nicholas +4 more
core +1 more source
Advanced Functional Materials, EarlyView.Bio‐based and (semi‐)synthetic zwitterion‐modified novel materials and fully synthetic next‐generation alternatives show the importance of material design for different biomedical applications. The zwitterionic character affects the physiochemical behavior of the material and deepens the understanding of chemical interaction mechanisms within the ...
Theresa M. Lutz +3 more
wiley +1 more source
Structure and Electrochemical Properties of ReS2‐LaFeO3 Nanocomposite for Dopamine Sensing
Advanced Sensor Research, EarlyView.A novel ReS2‐LaFeO3 nanocomposite is developed for sensitive and reliable detection of dopamine (DA), an important neurotransmitter. The material performs well even in complex biological samples, demonstrating strong selectivity and accuracy. These findings highlight its potential for future applications in medical diagnostics and neuroscience research.
Obed Graham Keelson +5 more
wiley +1 more source
Effect of Additives on the Morphology of γ‑Aminobutyric Acid Crystals [PDF]
ACS OmegaZhiying Pan +6 more
doaj +2 more sources
Shipin gongye ke-ji, 2022 In order to study the influence of different treatment methods on the nutritional composition and biological activity of rice buckwheat, germination, fermentation, steaming and fermentation after steaming on the reducing sugar, protein, free amino acids,
Jing YAN +5 more
doaj +1 more source
Disrupted GABAergic facilitation of working memory performance in people with schizophrenia. [PDF]
, 2020 ObjectivesGamma-Amiobutyric acid (GABA) is a primary inhibitory neurotransmitter that facilitates neural oscillations that coordinate neural activity between brain networks to facilitate cognition.
Carter, CS +7 more
core
Unanticipated differences between α- and γ-diaminobutyric acid-linked hairpin polyamide-alkylator conjugates [PDF]
, 2006 Hairpin polyamide–chlorambucil conjugates containing an {alpha}-diaminobutyric acid ({alpha}-DABA) turn moiety are compared to their constitutional isomers containing the well-characterized {gamma}-DABA turn.
Chou, C. James +4 more
core +4 more sources
Rewiring Neuroimmunity: Nanoplatform Innovations for CNS Disease Therapy
Advanced Therapeutics, EarlyView.This review explores emerging nanoplatform strategies designed to modulate neuroimmune responses for treating central nervous system (CNS) disorders. It examines structural and microenvironmental barriers, advances in multifunctional and targeted nanotechnologies, and highlights clinical progress and translational challenges, offering insights into the
Muhammad Usman Akbar +7 more
wiley +1 more source
Advanced Science, EarlyView.This study elucidates a novel SlJAZ8‐SlWRKY57‐SlAVT6A/SlAVT6B module that effectively channels metabolic flux from primary to secondary metabolism, impacting plant growth, development, and resistance. Two novel vacuolar amino acid exporters, SlAVT6A and SlAVT6B, fine‐tunes trichomes, terpenes, and gibberellins, bolstering spider mite resistance.
Yingchen Hao +11 more
wiley +1 more source