Results 81 to 90 of about 5,282,507 (400)

The Microbiota Shapes Central Nervous System Myelination in Early Life

open access: yesAdvanced Science, EarlyView.
Gut microbiota shapes brain development by regulating myelination and glial cell maturation in early life. Using germ‐free (GF) mice and zebrafish, this study reveals sex‐ and age‐dependent effects on myelin growth, integrity, and related gene expression.
Caoimhe M. K. Lynch   +13 more
wiley   +1 more source

Acrylamide neurotoxicity on the cerebrum of weaning rats

open access: yesNeural Regeneration Research, 2015
The mechanism underlying acrylamide-induced neurotoxicity remains controversial. Previous studies have focused on acrylamide-induced toxicity in adult rodents, but neurotoxicity in weaning rats has not been investigated.
Su-min Tian   +5 more
doaj   +1 more source

Effects of dietary supplementation of different levels of gamma-aminobutyric acid on reproductive performance, glucose intolerance, and placental development of gilts [PDF]

open access: green, 2023
Shuo Ma   +9 more
openalex   +1 more source

Uncovering the Lipid Interface in Neurotransmission: Single Molecule Measurements of Neurotransmitters Interacting with Membranes Reveal Species Dependent Membrane Binding

open access: yesAdvanced Science, EarlyView.
Using single‐molecule whispering gallery mode sensors, neurotransmitter‐specific membrane binding signatures are measured that reveal intrinsically distinct interaction kinetics and orientations on a lipid membrane. Abstract Neurotransmitters (NTs) have traditionally been understood to act via aqueous‐phase receptor binding, but growing evidence ...
Thomas L. Derrien   +4 more
wiley   +1 more source

Esketamine/Ketamine: Dual‐Action Mechanisms and Clinical Prospects beyond Anesthesia in Psychiatry, Immunology, and Oncology

open access: yesAdvanced Science, EarlyView.
Esketamine and ketamine are widely used for perioperative analgesia and anesthesia. Despite their established roles in analgesia, sedation, and anesthesia, as well as emerging antidepressant, anti‐tumor, and anti‐inflammatory effects, their clinical use is limited due to side effects and addiction potential.
Yinxin Wang   +7 more
wiley   +1 more source

Control of Bremia lactucae in Field-Grown Lettuce by DL-3-Amino-n-Butanoic Acid (BABA) [PDF]

open access: yes, 2007
DL-3-amino-n-butanoic acid (BABA) was effective in controlling downy mildew incited by Bremia lactucae Regel in lettuce plants. The two isomers of BABA, DL-2-amino-n-butanoic acid and 4-amino-butanoic acid and its s-enantiomer were ineffective compares ...
Baider, Alexander   +3 more
core  

The Arabidopsis Malectin-Like/LRR-RLK IOS1 is Critical for BAK1-Dependent and BAK1-Independent Pattern-Triggered Immunity [PDF]

open access: yes, 2016
Plasma membrane-localized pattern recognition receptors (PRRs) such as FLAGELLIN SENSING2 (FLS2), EF-TU RECEPTOR (EFR) and CHITIN ELICITOR RECEPTOR KINASE 1 (CERK1) recognize microbe-associated molecular patterns (MAMPs) to activate pattern-triggered ...
Chien, Hsiao-Chiao   +11 more
core   +1 more source

Structure‐Function Integration in 2D Hybrid Perovskite for Fast Neutron and Gamma Ray Discrimination

open access: yesAdvanced Science, EarlyView.
Using an in situ seed‐assisted cooling method, large (28 × 7 × 3 mm3) (GABA)2PbBr4 single crystals are grown, featuring hydrogen‐rich organic layers and a dense PbBr4 framework. This architecture enables efficient γ‐ray absorption, fast‐neutron sensitivity, and clear n/γ pulse‐shape discrimination (FOM up to 1.74), highlighting its potential as a ...
Yingming Wang   +15 more
wiley   +1 more source

Plant perception of β-aminobutyric acid is mediated by an aspartyl-tRNA synthetase

open access: yesNature Chemical Biology, 2014
Specific chemicals can prime the plant immune system for augmented defence. β-aminobutyric acid (BABA) is a priming agent that provides broad-spectrum disease protection.
Estrella Luna   +12 more
semanticscholar   +1 more source

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