Results 71 to 80 of about 277 (113)

The synthesis of N‐(ϵ‐aminocaproy L‐) ϵ‐aminocaproic acid. „Di‐ϵ‐aminocaproic acid”︁.

Recueil des Travaux Chimiques des Pays-Bas, 1952
AbstractThe possibility of synthesizing ω‐peptides by condensation of a ω‐phthalimido acid chloride with a ω‐amino acid and subsequent treatment with hydrazine has been investigated.The synthesis of N‐(ϵ‐aminocaproyl‐) ϵ‐aminocaproic acid is described.
Want, G.M. van der, Staverman, A.J.
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Aminocaproic Acid Prophylaxis in Traumatic Hyphema

Ophthalmic Surgery, Lasers and Imaging Retina, 1990
ABSTRACT Oral aminocaproic acid has been shown to be effective in clot stabilization and in the reduction of secondary bleeding rates in cases of traumatic hyphema. In a retrospective study of 105 patients treated during a 1-year period, we found the incidence of rebleeding in patients with traumatic hyphema who received aminocaproic acid ...
Thomas W. Wilson, John B. Jeffers, Leonard B Nelson   +2 more
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Effect of probenecid on the kinetics of epsilon-aminocaproic acid

Clinical Pharmacology and Therapeutics, 1980
Healthy male subjects received, 1 wk apart, single oral doses of epsilon-aminocaproic acid (EACA) 100 mg/kg alone, EACA within probenecid (0.5 gm), or EACA 2 hr after 2.0 gm probenecid. Probenecid (2.0 gm) reduced the 8-hr urinary clearance and recovery of EACA by 50% without affecting plasma kinetics.
Kerry L Katlic, Barry H. Dvorchik, Arthur H. Hayes, M. Elaine Eyster   +3 more
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Myoglobinuria Following Aminocaproic Acid Administration

JAMA: The Journal of the American Medical Association, 1976
To the Editor.— e-Aminocaproic acid (EACA), a specific inhibitor of plasminogen activation, was originally used in low dosage as an antifibrinolytic agent and is now being employed in higher doses in the treatment of hereditary angioneurotic edema. We have recently encountered a 24-year-old woman receiving high doses of EACA who had rhabdomyolysis and
Robert A. Rizza, Stuart Sclonick, C. Lockard Conley   +2 more
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Rhabdomyolysis Induced by Epsilon-Aminocaproic Acid

Annals of Pharmacotherapy, 1997
OBJECTIVE: To report a case of rhabdomyolysis associated with epsilon-aminocaproic acid (epsilon-ACA). CASE SUMMARY: A 33-year-old female patient with chronic granulocytic leukemia was treated with epsilon-ACA for approximately 3.5 months for thrombocytopenic bleeding. The initial dosage was 4 g po q6h.
Morel Rubinger, Beverly D Seymour
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Thrombosis with Epsilon Aminocaproic Acid Therapy

American Journal of Clinical Pathology, 1971
A patient with postoperative bleeding was treated with epsilon aminocaproic acid (EACA). Subsequent coagulation studies supported the diagnosis of intravascular coagulation and the patient subsequently developed renal failure due to glomerular thromboses.
Harvey R. Gralnick, Philip Greipp
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Aminocaproic Acid in the Treatment of Traumatic Hyphema

American Journal of Ophthalmology, 1976
Of 59 patients with traumatic hyphema studied prospectively, 32 received aminocaproic acid, an antifibrinolytic agent, to prevent secondary hemorrhage. The remaining 27 patients received placebo in an identical manner. Of the aminocaproic acid-treated patients, only one (3%) rebled, while nine patients (33%) receiving placebo suffered secondary ...
Earl R. Crouch, Marcel Frenkel
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Effect of  -Aminocaproic Acid on Postvitrectomy Hemorrhage

Archives of Ophthalmology, 1985
We performed a prospective study involving 96 patients undergoing vitrectomy for proliferative diabetic retinopathy to determine the effect of epsilon-aminocaproic acid on the occurrence of postoperative intraocular hemorrhage. epsilon-Aminocaproic acid significantly reduced postoperative vitreous hemorrhage during the immediate postoperative period ...
S. De Bustros, Bert M. Glaser, Cheryl Auer, Ronald G. Michels   +3 more
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Epsilon-Aminocaproic acid therapy in ulcerative colitis

The American Journal of Digestive Diseases, 1973
A double-blind cross-over trial of the effect of Epsilon-Aminocaproic acid (EACA) versus placebo on gastrointestinal blood loss in 13 patients with proctocolitis showed no statistically significant reduction in blood loss recorded by the disappearance rate, as detected by whole-body monitoring of parenterally administered59Fe.
K. Boddy, J. A. R. McIntosh, A. S. Douglas, P. W. Brunt, N. A. G. Mowat, Priscilla C. King   +5 more
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Epsilon Aminocaproic Acid — A Dangerous Weapon

New England Journal of Medicine, 1969
Of the body's defenses against injury, the proteolytic activity of plasmin, an enzyme that can evolve in plasma from an inert precursor, plasminogen, is most intriguing. Clinical attention has been centered upon the digestion of fibrin by plasmin, but this enzyme also digests other clotting factors, converts the first component of complement to its ...
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