Results 1 to 10 of about 4,991,140 (249)

Pharmacokinetics of p-Aminohippuric Acid and Inulin in Rabbits with Aristolochic Acid Nephropathy [PDF]

open access: goldAdvances in Pharmacological Sciences, 2011
The characteristics of aristolochic acid nephropathy (AAN) are interstitial fibrosis and atrophy of the proximal tubules, but with no change in glomeruli.
Chiao-Shih Tseng   +3 more
doaj   +9 more sources

Simultaneous Measurement of Glomerular Filtration Rate, Effective Renal Plasma Flow and Tubular Secretion in Different Poultry Species by Single Intravenous Bolus of Iohexol and Para-Aminohippuric Acid [PDF]

open access: goldAnimals, 2020
The aim of the current study was to investigate the simultaneous measurement of plasma p-aminohippuric acid (PAH) clearance as a potential marker to assess effective renal plasma flow (eRPF) and tubular secretion (TS), and the plasma clearance of iohexol
Lenka Stroobant   +7 more
doaj   +8 more sources

A combined pig model to determine the net absorption of volatile fatty acids in the large intestine under different levels of crude fiber [PDF]

open access: yesAnimal Models and Experimental Medicine, 2023
Background This study aimed to develop a combined model to quantify the net absorption of volatile fatty acids (VFA) in the large intestine (LI) of pigs. Methods Fifteen female growing pigs (Duroc × Large White × Landrace) were ranked by body weight (30 ±
Shengjun Zhao   +8 more
doaj   +3 more sources

Active Mammary Excretion of N4-Acetylated p-Aminohippuric Acid*) [PDF]

open access: bronzeActa Veterinaria Scandinavica, 1969
Different excretion patterns were observed for p-amino- hippuric acid and its acetylated metabolite in mammary excretion experiments in goats and cows. The excretion of p-aminohippuric acid conformed to passive diffusion of the non-protein bound and un-ionized fraction (Rasmussen 1958, 1966) as described by Miller et al. (1967).
Folke Rasmussen
semanticscholar   +5 more sources

The distribution of p-aminohippuric acid in rat kidney slices. I. Tubular localization

open access: bronzeKidney International, 1973
The distribution of p-aminohippuric acid in rat kidney slices. I. Tubular localization. Tubular localization of tritiated p-aminohippuric acid (PAH) was determined by section freeze-dry autoradiography in rat renal cortical slices in vitro. Autoradiographs were also prepared from tissue after incubation in tritiated alpha-aminoisobutyric acid (AIB ...
Richard P. Wedeen, Barry Weiner
semanticscholar   +5 more sources

The distribution of p-aminohippuric acid in rat kidney slices. II. Depth of uptake

open access: bronzeKidney International, 1973
The distribution of p-aminohippuric acid in rat kidney slices. II. Depth of uptake. Section freeze-dry autoradiography was used to measure the depth to which concentrative uptake of PAH-3H occurs within rat renal cortical slices in vitro under conditions of varied incubation time, temperature and PAH medium concentration.
Richard P. Wedeen, Barry Weiner
semanticscholar   +5 more sources

Synthesis of Some of Azo, Triazines and Schiff Bases Compounds from 4-Aminohippuric Acid [PDF]

open access: goldمجلة التربية والعلم, 2009
Three new series of 4-aminohippuric acid ester derivatives have been prepared. The azo (4a-f) and azoamino (5a-e) compounds were prepared from electrophilic addition reaction of 4-diazonium chloride hippuric acid ester with phenols, aniline and secondary
Mohammed Sheat   +2 more
doaj   +2 more sources

Unraveling the Contribution of Fluid Therapy to the Development of Augmented Renal Clearance in a Piglet Model [PDF]

open access: yesFrontiers in Pharmacology, 2021
Augmented renal clearance (ARC) observed in the critically ill pediatric population has received an increased attention over the last years due to its major impact on the disposition and pharmacokinetics of mainly renally excreted drugs.
Laura Dhondt   +7 more
doaj   +3 more sources

System Identification of the Low-Dose Kinetics of p-Aminohippuric Acid [PDF]

open access: greencclm, 1995
The renal clearance of p-aminohippuric acid, due to tubular secretion in addition to glomerular filtration, can only be determined by kinetic experiments. Maximal information can be gained from observed temporal marker concentration profiles by fitting dynamic mathematical models of the processes involved, such as absorption, distribution, and ...
Willibald Estelberger   +8 more
openalex   +4 more sources

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