Pharmacokinetics of p-Aminohippuric Acid and Inulin in Rabbits with Aristolochic Acid Nephropathy [PDF]
The characteristics of aristolochic acid nephropathy (AAN) are interstitial fibrosis and atrophy of the proximal tubules, but with no change in glomeruli.
Chiao-Shih Tseng +3 more
doaj +6 more sources
Simultaneous Measurement of Glomerular Filtration Rate, Effective Renal Plasma Flow and Tubular Secretion in Different Poultry Species by Single Intravenous Bolus of Iohexol and Para-Aminohippuric Acid [PDF]
The aim of the current study was to investigate the simultaneous measurement of plasma p-aminohippuric acid (PAH) clearance as a potential marker to assess effective renal plasma flow (eRPF) and tubular secretion (TS), and the plasma clearance of iohexol
Lenka Stroobant +7 more
doaj +8 more sources
Novel Derivatives of Nitrobenzofurazan with Chromogenic and Fluorogenic Properties [PDF]
Five new derivatives were obtained utilizing 4-chloro-7-nitrobenzofurazan (NBD-chloride) in combination with furfurylamine, adamantylamine, aminohippuric acid, phenylalanine, and dehydroabietylamine. These derivatives were then subjected to a comparative
Alexandru Bujor +7 more
doaj +2 more sources
In nutrition studies, para-aminohippuric acid (PAH) is a marker frequently used to measure blood flow in pigs, which is essential for estimating portal-drained viscera (PDV) flux of nutrients.
I. Fernández-Fígares +3 more
doaj +2 more sources
System Identification of the Low-Dose Kinetics of p-Aminohippuric Acid [PDF]
The renal clearance of p-aminohippuric acid, due to tubular secretion in addition to glomerular filtration, can only be determined by kinetic experiments. Maximal information can be gained from observed temporal marker concentration profiles by fitting dynamic mathematical models of the processes involved, such as absorption, distribution, and ...
Estelberger, Willibald +8 more
openaire +5 more sources
Antiviral Activity of Acetylsalicylic Acid against Bunyamwera Virus in Cell Culture [PDF]
The Bunyavirales order is a large group of RNA viruses that includes important pathogens for humans, animals and plants. With high-throughput screening of clinically tested compounds we have looked for potential inhibitors of the endonuclease domain of a
Sara Yolanda Fernández-Sánchez +3 more
doaj +2 more sources
Glucosuria Interferes With Measurement of Effective Renal Plasma Flow Using para-Aminohippuric Acid, With a Focus on SGLT2 Inhibitors. [PDF]
Scholtes RA +6 more
europepmc +2 more sources
Para-aminohippuric acid (PAH) serves as a pivotal marker widely employed for accurately estimating effective renal plasma flow, playing a crucial role in the diagnosis and determination of various PAH-related diseases. Consequently, it arises a necessity
Sopan Nangare, Minal Patil, Pravin Patil
doaj +2 more sources
Active Mammary Excretion of N4-Acetylated p-Aminohippuric Acid*) [PDF]
Different excretion patterns were observed for p-amino- hippuric acid and its acetylated metabolite in mammary excretion experiments in goats and cows. The excretion of p-aminohippuric acid conformed to passive diffusion of the non-protein bound and un-ionized fraction (Rasmussen 1958, 1966) as described by Miller et al. (1967).
Folke Rasmussen
openaire +3 more sources
Rationale and study design of a randomized controlled trial to investigate the renoprotective effect of canagliflozin assessed by test of renal hemodynamics in diabetic kidney disease (the FAGOTTO study) [PDF]
Background Sodium-glucose cotransporter 2 inhibitors (SGLT2i) are considered to have the potential to maintain renal function by correcting glomerular hypertension in patients with diabetic kidney disease (DKD).
Sawako Kato +5 more
doaj +2 more sources

