Pharmacokinetics of p-Aminohippuric Acid and Inulin in Rabbits with Aristolochic Acid Nephropathy [PDF]
Advances in Pharmacological Sciences, 2011 The characteristics of aristolochic acid nephropathy (AAN) are interstitial fibrosis and atrophy of the proximal tubules, but with no change in glomeruli.
Chiao-Shih Tseng +3 more
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Simultaneous Measurement of Glomerular Filtration Rate, Effective Renal Plasma Flow and Tubular Secretion in Different Poultry Species by Single Intravenous Bolus of Iohexol and Para-Aminohippuric Acid [PDF]
Animals, 2020 The aim of the current study was to investigate the simultaneous measurement of plasma p-aminohippuric acid (PAH) clearance as a potential marker to assess effective renal plasma flow (eRPF) and tubular secretion (TS), and the plasma clearance of iohexol
Lenka Stroobant +7 more
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A combined pig model to determine the net absorption of volatile fatty acids in the large intestine under different levels of crude fiber [PDF]
Animal Models and Experimental Medicine, 2023 Background This study aimed to develop a combined model to quantify the net absorption of volatile fatty acids (VFA) in the large intestine (LI) of pigs. Methods Fifteen female growing pigs (Duroc × Large White × Landrace) were ranked by body weight (30 ±
Shengjun Zhao +8 more
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Synthesis of Some of Azo, Triazines and Schiff Bases Compounds from 4-Aminohippuric Acid [PDF]
مجلة التربية والعلم, 2009 Three new series of 4-aminohippuric acid ester derivatives have been prepared. The azo (4a-f) and azoamino (5a-e) compounds were prepared from electrophilic addition reaction of 4-diazonium chloride hippuric acid ester with phenols, aniline and secondary
Mohammed Sheat +2 more
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Novel Derivatives of Nitrobenzofurazan with Chromogenic and Fluorogenic Properties [PDF]
Molecules, 2023 Five new derivatives were obtained utilizing 4-chloro-7-nitrobenzofurazan (NBD-chloride) in combination with furfurylamine, adamantylamine, aminohippuric acid, phenylalanine, and dehydroabietylamine. These derivatives were then subjected to a comparative
Alexandru Bujor +7 more
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Active Mammary Excretion of N4-Acetylated p-Aminohippuric Acid*) [PDF]
Acta Veterinaria Scandinavica, 1969 Different excretion patterns were observed for p-amino- hippuric acid and its acetylated metabolite in mammary excretion experiments in goats and cows. The excretion of p-aminohippuric acid conformed to passive diffusion of the non-protein bound and un-ionized fraction (Rasmussen 1958, 1966) as described by Miller et al. (1967).
Folke Rasmussen
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Unraveling the Contribution of Fluid Therapy to the Development of Augmented Renal Clearance in a Piglet Model [PDF]
Frontiers in Pharmacology, 2021 Augmented renal clearance (ARC) observed in the critically ill pediatric population has received an increased attention over the last years due to its major impact on the disposition and pharmacokinetics of mainly renally excreted drugs.
Laura Dhondt +7 more
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Antiviral Activity of Acetylsalicylic Acid against Bunyamwera Virus in Cell Culture [PDF]
Viruses, 2023 The Bunyavirales order is a large group of RNA viruses that includes important pathogens for humans, animals and plants. With high-throughput screening of clinically tested compounds we have looked for potential inhibitors of the endonuclease domain of a
Sara Yolanda Fernández-Sánchez +3 more
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Rationale and study design of a randomized controlled trial to investigate the renoprotective effect of canagliflozin assessed by test of renal hemodynamics in diabetic kidney disease (the FAGOTTO study) [PDF]
BMC Nephrology, 2023 Background Sodium-glucose cotransporter 2 inhibitors (SGLT2i) are considered to have the potential to maintain renal function by correcting glomerular hypertension in patients with diabetic kidney disease (DKD).
Sawako Kato +5 more
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System Identification of the Low-Dose Kinetics of p-Aminohippuric Acid [PDF]
cclm, 1995 The renal clearance of p-aminohippuric acid, due to tubular secretion in addition to glomerular filtration, can only be determined by kinetic experiments. Maximal information can be gained from observed temporal marker concentration profiles by fitting dynamic mathematical models of the processes involved, such as absorption, distribution, and ...
Estelberger, Willibald +8 more
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