Results 11 to 20 of about 3,027 (250)

A combined pig model to determine the net absorption of volatile fatty acids in the large intestine under different levels of crude fiber

Animal Models and Experimental Medicine, 2023
Background This study aimed to develop a combined model to quantify the net absorption of volatile fatty acids (VFA) in the large intestine (LI) of pigs. Methods Fifteen female growing pigs (Duroc × Large White × Landrace) were ranked by body weight (30 ±
Shengjun Zhao, Liangkang Lv, Taotao Wu, Zhi Feng, Qiang Li, Long Lei, Zhengya Liu, Hui Zhang, Ying Ren   +8 more
doaj   +2 more sources

Effects of Combination Treatment on Renal Endothelial Function in Type 2 Diabetes Mellitus [PDF]

Kidney International Reports
Introduction: Recently, we demonstrated that a combination therapy with empagliflozin and linagliptin (E+L) in patients with type 2 diabetes mellitus (T2DM) induce changes in renal hemodynamics.
Merve Günes-Altan, Agnes Bosch, Kristina Striepe, Mario Schiffer, Roland E. Schmieder, Dennis Kannenkeril   +5 more
doaj   +2 more sources

Investigation of Complex Equilibria in Solutions of p-Aminohippuric Acid and Tin (II) Ion in Perchlorate Medium [PDF]

Reviews in Analytical Chemistry, 2004
Jankovic, Drina, Djokic, Divna
doaj   +2 more sources

Significant association between glycemic status and increased estimated postglomerular resistance in nondiabetic subjects - study of inulin and para-aminohippuric acid clearance in humans. [PDF]

Physiol Rep, 2015
Yasumoto M, Tsuda A, Ishimura E, Uedono H, Ohno Y, Ichii M, Ochi A, Nakatani S, Mori K, Uchida J, Emoto M, Nakatani T, Inaba M.   +12 more
europepmc   +3 more sources

Unveiling mechanisms underlying kidney function changes during sex hormone therapy [PDF]

The Journal of Clinical Investigation
BACKGROUND Men with chronic kidney disease (CKD) experience faster kidney function decline than women. Studies in individuals undergoing sex hormone therapy suggest a role for sex hormones, as estimated glomerular filtration rate (eGFR) increases with ...
Sarah A. van Eeghen, Laura Pyle, Phoom Narongkiatikhun, Ye Ji Choi, Wassim Obeid, Chirag R. Parikh, Taryn G. Vosters, Irene G.M. van Valkengoed, Merle M. Krebber, Daan J. Touw, Martin den Heijer, Petter Bjornstad, Daniël H. van Raalte, Natalie J. Nokoff   +13 more
doaj   +2 more sources

Population Physiologically-Based Pharmacokinetic Modeling to Determine Ontogeny: A Quantitative Clinical Pharmacology Example in Pediatric Rare Disease. [PDF]

CPT Pharmacometrics Syst Pharmacol
ABSTRACT Pediatric physiologically‐based pharmacokinetic (PBPK) modelling plays an increasing role in selecting doses in children and addressing clinical pharmacology questions. Ethical concerns often limit clinical pharmacology studies that have no direct therapeutic benefit in children, highlighting the value of PBPK model predictions.
Cleary Y, Prasad B, Ogungbenro K, Gertz M, Galetin A.   +4 more
europepmc   +2 more sources

Circulating amino acids and amino acid-related metabolites and risk of breast cancer among predominantly premenopausal women

npj Breast Cancer, 2021
Known modifiable risk factors account for a small fraction of premenopausal breast cancers. We investigated associations between pre-diagnostic circulating amino acid and amino acid-related metabolites (N = 207) and risk of breast cancer among ...
Oana A. Zeleznik, Raji Balasubramanian, Yibai Zhao, Lisa Frueh, Sarah Jeanfavre, Julian Avila-Pacheco, Clary B. Clish, Shelley S. Tworoger, A. Heather Eliassen   +8 more
doaj   +1 more source

Measurement of urinary para-aminohippuric acid in glycosurie diabetics

Kidney International, 1988
Neil Dalton, R., Wiseman, Martin J., Turner, Charles, Viberti, Giancarlo   +3 more
openaire   +3 more sources

Age‐dependent changes in the gut microbiota and serum metabolome correlate with renal function and human aging

Aging Cell, Volume 22, Issue 12, December 2023., 2023
A comprehensive analysis of the gut metagenome and serum metabolome of individuals from a Chinese longevity cohort. We discovered distinct age‐dependent differences in both microbiota and serum metabolome. Through mediation analyses and fecal microbiota transplantation, we uncovered a potential causal relationship between the microbiota and metabolite ...
Liang Sun, Zhiming Li, Caiyou Hu, Jiahong Ding, Qi Zhou, Guofang Pang, Zhu Wu, Ruiyue Yang, Shenghui Li, Jian Li, Jianping Cai, Yuzhe Sun, Rui Li, Hefu Zhen, Shuqin Sun, Jianmin Zhang, Mingyan Fang, Zhihua Chen, Yuan Lv, Qizhi Cao, Yanan Sun, Ranhui Gong, Zezhi Huang, Yong Duan, Hengshuo Liu, Jun Dong, Junchun Li, Jie Ruan, Haorong Lu, Benjin He, Ninghu Li, Tao Li, Wenbin Xue, Yan Li, Juan Shen, Fan Yang, Cheng Zhao, Qinghua Liang, Mingrong Zhang, Chen Chen, Huan Gong, Yong Hou, Jian Wang, Ying Zhang, Huanming Yang, Shida Zhu, Liang Xiao, Zhen Jin, Haiyun Guo, Peng Zhao, Susanne Brix, Xun Xu, Huijue Jia, Karsten Kristiansen, Ze Yang, Chao Nie   +55 more
wiley   +1 more source

Maternal dexamethasone exposure does not affect glucose tolerance but alters renal haemodynamics in F1 rats in a sex‐dependent manner

Endocrinology, Diabetes &Metabolism, Volume 6, Issue 6, November 2023., 2023
Maternal dexamethasone treatment caused glomerular hypertrophy and a decline in renal function and effective renal plasma flow in 4‐month‐old male offspring with no changes detected in females of the same age. The expression of sodium‐glucose transporter‐2 in renal membrane fractions was not affected by dexamethasone treatment suggesting that it does ...
Slava A. Malatiali, Narayana Kilarkaje, Maie Al‐Bader   +2 more
wiley   +1 more source