Results 191 to 200 of about 3,027 (250)
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Clearance of para-aminohippuric acid in wethers consuming locoweed

New Zealand Veterinary Journal, 2005
To validate the use of para-aminohippuric acid (PAH) as a marker for measuring blood flow in wethers consuming a mixed diet of locoweed and blue grama hay.Fourteen sheep, stratified by bodyweight (BW), were assigned to one of three treatments: 0.8 mg swainsonine (SW)/kg BW (HI), 0.2 mg SW/kg BW (LO), and no SW (Control).
J R, Strickland   +5 more
openaire   +2 more sources

Probenecid infusion in mares: Effect on para-aminohippuric acid clearance

American Journal of Veterinary Research, 1988
SUMMARY Para-aminohippuric acid (paha, 0.1 mg/min/kg of body weight) was infused iv into 2 mares, followed by concurrent iv infusion of paha and probenecid (0.075, 0.15, 0.25, or 0.35 mg of probenecid/min/kg). Probenecid infusion reduced the clearance of paha at serum probenecid concentrations > 55 μg/ml.
R, Gronwall, M P, Brown
openaire   +2 more sources

Technetium-99m Labeled p-Aminohippuric Acid Analogues: Renal Function Agents

Journal of Pharmaceutical Sciences, 1989
A number of p-aminohippuric acid analogues were synthesized in order to develop clinically useful 99mTc-labeled radiopharmaceuticals for evaluation of renal function measurements. Stable 99mTc-labeled complexes were formed at pH 5.7 using a Sn(II) reduction method with all derivatives.
Z, Zhang   +4 more
openaire   +2 more sources

p-Aminohippuric acid accumulation in kidney slices in cloudy swelling

Experientia, 1959
L'incorporazione dell'acidop-aminoippurico nelle sezioni di rene di ratto e diminuita nel rigonfiamento torbido provocato dal trattamento parenterale con tossina stafilococcioa, con dinitrofenolo o con tiroxina. Tutti questi trattamenti provocano anche dissociazione delle fosforilazioni dalle ossidazioni.
B, FIDA, G C, BIAGGINI, M U, DIANZANI
openaire   +2 more sources

Simultaneous determination of p-aminohippuric acid, acetyl-p-aminohippuric acid and iothalamate in human plasma and urine by high-performance liquid chromatography

Journal of Chromatography B: Biomedical Sciences and Applications, 1998
A sensitive and specific high-performance liquid chromatographic assay was developed for the simultaneous determination of p-aminohippuric acid (PAH), acetyl-p-aminohippuric acid (aPAH), and iothalamate in human plasma and urine. Plasma samples were prepared by protein precipitation with acetonitrile followed by evaporation, reconstitution in mobile ...
T C, Dowling, R F, Frye, M A, Zemaitis
openaire   +2 more sources

The metabolism of p-aminohippuric acid and p-acetylamino-hippuric acid

Clinica Chimica Acta, 1967
Abstract p-Aminohippuric acid or p-acetylaminohippuric acid administered to patients orally instead of intravenously as a method to determine their kidney function was found to give erroneously low clearance values. It was found that these compounds lost the glycine moiety by hydrolysis in the alimentary tract and were converted in the tissues to ...
W.C. Hülsmann, L.W.Statius Van Eps
openaire   +1 more source

Clearance Determinations After Oral Administration of Para-Aminohippuric Acid

Scandinavian Journal of Clinical and Laboratory Investigation, 1950
1) The substance was absorbed and demonstrable in both plasma and urine. 2) The concentrations were of the same Brun, IIilden & Raaschou (.lcta Yed. Scand. 121: 171 : 1917) claim to have demonstrated 110 relative magnitude, but generally lower PXH, either in plasma or in urine, after oral than those observed by Hamburger 8r administration of 4 grams of
N. R. Hågensen, R. Keiding, V. Schmidt
openaire   +1 more source

Nalidixic Acid: Intrarenal Distribution and Its Effect Upon Para-Aminohippurate Excretion

Journal of Urology, 1975
Studies performed on the intrarenal distribution of nalidixic acid in dogs show that this weak organic acid is indeed accumulated in the kidney, the highest concentration being attained in the cortex and followed in order by the outer medulla, papillae, and inner cortex. Our results also show that nalidixic acid produces significant changes in the para-
J, Santos-Martinez, J R, Diaz
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[Para-aminohippuric acid secretion by the vertebrate kidney].

Zhurnal evoliutsionnoi biokhimii i fiziologii, 1978
Tubular secretory capacity has been investigated in the kidney of marine fishes Scorpaena porcus, Spicara smaris, frog Rana ridibunda and albino rat by determination of maximal transport of p-aminohippurate--TmPAH, Following values of Tmax expressed in mg/hour per 100 g of body weight were obtained: 0.73 +/- 0.17 for S.
openaire   +1 more source

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