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Clinical investigations of 99mTc–p-aminohippuric acid as a new renal agent
Nuclear Medicine Communications, 200999mTc-p-aminohippuric acid (PAH) is a new radiopharmaceutical rapidly secreted by the kidneys in a manner consistent with tubular secretion. A comparative study of renal scintigraphy and clearance with 99mTc-PAH, diethylene triamine pentaacetic acid (DTPA) and mercaptoacetyltriglycine (MAG,) was performed.99mTc-PAH was prepared from a lyophilized kit ...
D. Djokić+7 more
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p-Aminohippuric acid transport into brush border vesicles isolated from flounder kidney.
American Journal of Physiology, 1979p-Aminohippuric acid (PAH) transport was investigated in brush border vesicles isolated from renal proximal tubules of the winter flounder. Three characteristics of carrier-mediated transport were demonstrated: 1) unlabeled PAH inhibited the uptake of ...
J. Eveloff, R. Kinne, W. B. Kinter
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Effect of splanchnicotomy on the renal excretion of para-aminohippuric acid in the anaesthetized dog
Pfl�gers Archiv European Journal of Physiology, 1977Renal excretion of para-aminohippuric acid (PAH) was studied during PAH loading on unilaterally splanchnicotomized ("denervated") anaesthetized dogs. Urine flow, sodium excretion of denervated kidneys were significantly increased. Below a plasma concentration of 20 mg% there were no differences between intact and denervated kidneys in urinary excretion
P. Bencsath, L. Takacs, L. Szalay
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Biochemical and Biophysical Research Communications - BBRC, 2000
Organic anions are secreted into urine via organic anion transporters across the renal basolateral and apical membranes. However, no apical membrane transporter for organic anions such as p-aminohippuric acid (PAH) has yet been identified. In the present
Hiroshi Uchino+8 more
semanticscholar +1 more source
Organic anions are secreted into urine via organic anion transporters across the renal basolateral and apical membranes. However, no apical membrane transporter for organic anions such as p-aminohippuric acid (PAH) has yet been identified. In the present
Hiroshi Uchino+8 more
semanticscholar +1 more source
Synthesis of p-aminohippuric acid analog and its labeling by technetium-99m
International Journal of Radiation Applications and Instrumentation. Part A. Applied Radiation and Isotopes, 1989A procedure is described for the synthesis of p-[(bisacarboxymethyl)aminomethyl carbamino] hippuric acid (PAHIDA). The compound was identified by i.r. and NMR spectroscopy. A lyophilized complex was prepared and labeled with 99mTc. The purity of the preparation is better than 98%. The stability of the 99mTc-PAHIDA complex is achieved 8 h after labeling.
Bogdanova+5 more
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Conformational profile and vibrational assignments of hippuric and 4-aminohippuric acids
Journal of Molecular Structure, 2011Abstract The structural stability of hippuric acid and 4-aminohippuric acid was investigated for comparison purpose by the DFT-B3LYP and ab initio MP2 calculations with the 6-311G ** basis set. From the calculations at both levels of theory the near-planar Ctcnp structure was predicted to be the lowest energy minimum for the two acids.
Abdulaziz A. Al-Saadi, Hassan M. Badawi
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In Analysis, 1999
Inulin and p-aminohippuric acid (PAH) clearances are used for the estimation of glomerular filtration rate (GFR) and effective renal plasma flow (ERPF).
N. Baccard+5 more
semanticscholar +1 more source
Inulin and p-aminohippuric acid (PAH) clearances are used for the estimation of glomerular filtration rate (GFR) and effective renal plasma flow (ERPF).
N. Baccard+5 more
semanticscholar +1 more source
Maximum Tubular Transport of <i>p</i>-Aminohippuric Acid in Sheep
Nephron, 1971Titration of the renal tubular secretory system for PAH was carried out in 5 unanesthetized sheep. The mean maximum rate of secretion was 2 mg/min/kg body weight.
D.T. Warren+3 more
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