Results 31 to 40 of about 2,744 (222)
Diabetes, Obesity and Metabolism, Volume 25, Issue 1, Page 198-207, January 2023., 2023 Abstract Aim To study the effects of the sodium‐glucose co‐transporter‐2 (SGLT2) inhibitor empagliflozin, the angiotensin receptor blocker (ARB) losartan, and their combination on blood pressure, while studying the mechanisms potentially involved. Methods A total of 24 people with type 2 diabetes (T2D) (age: 66 ± 6 years; body mass index: 31.0 ± 3 kg ...
Rosalie A. Scholtes +5 more
wiley +1 more source
Investigation of the Effect of Lead Adsorption on Surface Modified Fish Bones
Acta Natura et Scientia, 2020 This study investigates lead (Pb) elimination of surface modified fish bones as a biogenic apatite source. Surface modification was performed with 4-Aminohippuric acid (MBA1) and 2-Thiophenecarboxaldehyde (MBA2).
Bayram Kızılkaya, Evren Tan
doaj +1 more source
Physiological Reports, Volume 10, Issue 15, August 2022., 2022 Abstract Exercise is restricted for individuals with reduced renal function because exercising reduces blood flow to the kidneys. Safe and effective exercise programs for individuals with reduced renal function have not yet been developed. We previously examined the relationship between exercise intensity and renal blood flow (RBF), revealing that ...
Shotaro Kawakami +10 more
wiley +1 more source
Animals, 2023 Iberian pigs have low rates of muscle protein deposition compared with modern breeds. Differences in net portal appearance (NPA) of amino acids (AA) might partially explain that. NPA of AA was measured in six Iberian and six Landrace gilts (28 kg) fitted
Manuel Lachica +3 more
doaj +1 more source
Clinical Pharmacology &Therapeutics, Volume 111, Issue 6, Page 1222-1238, June 2022., 2022 Contrast‐induced nephropathy (CIN) is a major complication of imaging in patients with chronic kidney disease (CKD). The publication of an academic randomized controlled trial (RCT; n = 83) reporting oral (N)‐acetylcysteine (NAC) to reduce CIN led to > 70 clinical trials, 23 systematic reviews, and 2 large RCTs showing no benefit.
Euan A. Sandilands +20 more
wiley +1 more source
BMC Biology, 2020 Background Subclinical atherosclerosis may result in fatal cardiovascular (CV) events, but the underlying mechanisms and molecular players leading to disease are not entirely understood.
Marta Agudiez +8 more
doaj +1 more source
Frontiers in Pharmacology, 2020 Over recent years, pigs have been promoted as potential animal model due to their anatomical and physiological similarities with humans. However, information about the contribution of distinct renal elimination processes [glomerular filtration rate (GFR),
Laura Dhondt +16 more
doaj +1 more source
Blood L-cystine levels positively related to increased risk of hypertension. [PDF]
J Clin Hypertens (Greenwich)Abstract Hypertension is one component of metabolic syndrome (MetS). Here, the study evaluated hypertension‐associated metabolites in relation to other MetS components. Fasting plasma samples were collected from 22 hypertensive and 63 normotensive subjects for non‐targeted metabolomics.
Chen H +7 more
europepmc +2 more sources
Synthesis of novel azo compounds containing 5(4H)-oxazolone ring as potent tyrosinase inhibitors [PDF]
, 2013 Six new azo dyes containing of 5(4H)-oxazolone ring were prepared by diazotization of 4-aminohippuric acid and coupling with N,N-dimethylaniline, 1-naphthol and 2-naphthol and condensation with 4-fluoro benzaldehyde or 4-trifluoromethoxy benzaldehyde ...
Abbasalipour, V. +5 more
core +1 more source
Pharmacology Research &Perspectives, Volume 10, Issue 3, June 2022., 2022 Mechanistic static pharmacokinetic models predict that CYP450 inhibition and induction are unlikely for fenfluramine or its major metabolite norfenfluramine at doses used for seizure reduction (0.2−0.7 mg/kg/day). These results suggest minimal drug‐drug interaction perpetrator potential for either fenfluramine or norfenfluramine.
Parthena Martin +5 more
wiley +1 more source