The synthesis of some acylglycines and related oxazolones [PDF]
No description ...
Acheson, R M+3 more
core +1 more source
Volume-sensitive anion channels mediate osmosensitive glutathione release from rat thymocytes. [PDF]
Glutathione (GSH) is a negatively charged tripeptide, which is a major determinant of the cellular redox state and defense against oxidative stress. It is assembled inside and degraded outside the cells and is released under various physiological and ...
Ravshan Z Sabirov+3 more
doaj +1 more source
Non-contrast renal magnetic resonance imaging to assess perfusion and corticomedullary differentiation in health and chronic kidney disease [PDF]
AIMS Arterial spin labelling (ASL) MRI measures perfusion without administration of contrast agent. While ASL has been validated in animals and healthy volunteers (HVs), application to chronic kidney disease (CKD) has been limited. We investigated the
Delles, Christian+9 more
core +1 more source
Evaluation of Glycated Albumin (GA) and GA/Hba1c Ratio for Diagnosis of Diabetes and Glycemic Control: A Comprehensive Review [PDF]
Diabetes Mellitus (DM) is a group of metabolic diseases characterized by chronic high blood glucose concentrations (hyperglycemia). When it is left untreated or improperly managed, it can lead to acute complications including diabetic ketoacidosis and ...
Abdolrahim, Mojgan+6 more
core +3 more sources
Demonstration that Para-aminohippuric Acid "Enters" the Human Erythrocyte.
Conclusions(1) Contrary to previous reports in the literature para-aminohippuric acid (PAH) has been found to “enter” the human erythrocyte at low and high plasma PAH concentrations. (2) It is pointed out that PAH plasma extraction will be falsely low and renal plasma flow estimation from the extraction values will be falsely high unless renal venous ...
Gordon B. Magill+3 more
openaire +3 more sources
Development of a Dynamic Physiologically Based Mechanistic Kidney Model to Predict Renal Clearance
Renal clearance is usually predicted via empirical approaches including quantitative structure activity relationship and allometric scaling. Recently, mechanistic prediction approaches using in silico kidney models have been proposed.
Weize Huang, Nina Isoherranen
doaj +1 more source
Effect of Acetazolamide on Obesity-Induced Glomerular Hyperfiltration: A Randomized Controlled Trial. [PDF]
Obesity is an important risk factor for the development of chronic kidney disease. One of the major factors involved in the pathogenesis of obesity-associated kidney disease is glomerular hyperfiltration.
Boris Zingerman+7 more
doaj +1 more source
Augmented renal clearance (ARC) as observed in the critically ill (pediatric) population can have a major impact on the pharmacokinetics and posology of renally excreted drugs.
Laura Dhondt+9 more
doaj +1 more source
Role of hydrophobic interaction in hapten-antibody binding [PDF]
The precipitation reaction of bovine serum albumin coupled with p-azophenylleucine with homologous antibody was inhibited by several structurally related haptens. The isobutyl group substituent on alpha-carbon atom of the leucine residue contributed more
Hatase, Osamu+5 more
core +1 more source
Association of Noise Annoyance with Measured Renal Hemodynamic Changes
Background: Chronic mental stress is recognized as a modifiable risk factor for cardiovascular disease. The aim of this study was to demonstrate that noise annoyance-induced stress is associated with changes in renal hemodynamics.
Dennis Kannenkeril+6 more
doaj +1 more source