Multiple blood-brain barrier transport mechanisms limit bumetanide accumulation, and therapeutic potential, in the mammalian brain [PDF]
, 2017 There is accumulating evidence that bumetanide, which has been used over decades as a potent loop diuretic, also exerts effects on brain disorders, including autism, neonatal seizures, and epilepsy, which are not related to its effects on the kidney but ...
Erker, Thomas +7 more
core +2 more sources
Aluminum Poisoning with Emphasis on Its Mechanism and Treatment of Intoxication
Emergency Medicine International, Volume 2022, Issue 1, 2022., 2022 Aluminum poisoning has been reported in some parts of the world. It is one of the global health problems that affect many organs. Aluminum is widely used daily by humans and industries. Residues of aluminum compounds can be found in drinking water, food, air, medicine, deodorants, cosmetics, packaging, many appliances and equipment, buildings ...
Mehrdad Rafati Rahimzadeh +6 more
wiley +1 more source
Splanchnic metabolism of nutrients and hormones in steers fed alfalfa under conditions of increased absorption of ammonia and L-arginine supply across the portal-drained viscera [PDF]
, 2005 Effects of increased ammonia and/or arginine absorption on net splanchnic (portal-drained viscera [PDV] plus liver) metabolism of nonnitrogenous nutrients and hormones in cattle were examined.
Assan +42 more
core +1 more source
BioMed Research International, Volume 2022, Issue 1, 2022., 2022 Berberis baluchistanica Ahrendt is a medicinal plant potentially known for the treatment of different diseases. The bioactive, antioxidant, nutritional components, and antimicrobial properties of crude ethanolic root extract of Berberis baluchistanica were evaluated in this study.
Zareen Gul +12 more
wiley +1 more source
Deciphering the Metabolomics‐Based Intervention of Yanghe Decoction on Hashimoto’s Thyroiditis
Evidence-Based Complementary and Alternative Medicine, Volume 2022, Issue 1, 2022., 2022 Background. Yanghe decoction is a famous formula consisting of Rehmannia, deer horn gum, cinnamon, rue, Ephedra, ginger charcoal, and licorice. However, few studies have explored the role of the potential mechanism of Yanghe decoction in the treatment of Hashimoto’s thyroiditis by metabolomics. Methods. Nine mice were randomly divided into three groups:
Xing Zhang +4 more
wiley +1 more source
Kidney & Blood Pressure Research, 2020 Background: Cr is secreted by the proximal tubules and thus Cr clearance (Ccr) can overestimate inulin clearance (Cin). However, in some cases, Ccr can even underestimate Cin. This suggests that Cr could be reabsorbed in the tubuli.
Akihiro Tsuda +7 more
doaj +1 more source
HPLC estimation of iothalamate to measure glomerular filtration rate in humans [PDF]
, 2016 Glomerular filtration rate (GFR) is usually determined by estimation of iothalamate (IOT) clearance. We have developed and validated an accurate and robust method for the analysis of IOT in human plasma and urine.
Ashraf, Syed Salman +4 more
core +1 more source
The synthesis of some acylglycines and related oxazolones [PDF]
, 1960 No description ...
Acheson, R M +3 more
core +1 more source
Volume-sensitive anion channels mediate osmosensitive glutathione release from rat thymocytes. [PDF]
PLoS ONE, 2013 Glutathione (GSH) is a negatively charged tripeptide, which is a major determinant of the cellular redox state and defense against oxidative stress. It is assembled inside and degraded outside the cells and is released under various physiological and ...
Ravshan Z Sabirov +3 more
doaj +1 more source
Evaluation of Glycated Albumin (GA) and GA/Hba1c Ratio for Diagnosis of Diabetes and Glycemic Control: A Comprehensive Review [PDF]
, 2017 Diabetes Mellitus (DM) is a group of metabolic diseases characterized by chronic high blood glucose concentrations (hyperglycemia). When it is left untreated or improperly managed, it can lead to acute complications including diabetic ketoacidosis and ...
Abdolrahim, Mojgan +6 more
core +3 more sources