Results 61 to 70 of about 2,744 (222)

Allium sativum aqueous extract prevents potassium dichromate-induced nephrotoxicity and lipid oxidation in rats [PDF]

open access: yesJournal of Pharmacy & Pharmacognosy Research, 2014
Context: The potassium dichromate (K2Cr2O7) induces nephrotoxicity by oxidative stress mechanisms. Aims: To study the potential protection of an aqueous extract of Allium sativum against the K2Cr2O7-induced nephrotoxicity and lipid oxidation in rats ...
Sergio L. Becerra-Torres   +3 more
doaj  

Renal hemodynamic and morphological changes after 7 and 28 days of leptin treatment: the participation of angiotensin II via the AT1 receptor. [PDF]

open access: yesPLoS ONE, 2015
The role of hyperleptinemia in cardiovascular diseases is well known; however, in the renal tissue, the exact site of leptin's action has not been established.
Karina Thieme, Maria Oliveira-Souza
doaj   +1 more source

Renal hemodynamic effects differ between antidiabetic combination strategies: randomized controlled clinical trial comparing empagliflozin/linagliptin with metformin/insulin glargine

open access: yesCardiovascular Diabetology, 2021
Background Type 2 diabetes causes cardio-renal complications and is treated with different combination therapies. The renal hemodynamics profile of such combination therapies has not been evaluated in detail.
Christian Ott   +9 more
doaj   +1 more source

Early detection of ketoprofen-induced acute kidney injury in sheep as determined by evaluation of urinary enzyme activities [PDF]

open access: yes, 2010
Peer ...
Honkavaara, Matti Juhana   +9 more
core   +1 more source

Urinary Excretion of Tetrodotoxin Modeled in a Porcine Renal Proximal Tubule Epithelial Cell Line, LLC-PK1

open access: yesMarine Drugs, 2017
This study examined the urinary excretion of tetrodotoxin (TTX) modeled in a porcine renal proximal tubule epithelial cell line, LLC-PK1. Time course profiles of TTX excretion and reabsorption across the cell monolayers at 37 °C showed that the amount of
Takuya Matsumoto   +6 more
doaj   +1 more source

The Prolonging Action of Penicillin by Para-Aminohippuric Acid.

open access: yesExperimental Biology and Medicine, 1945
Conclusions1. When the plasma para-aminohippuric acid concentration was maintained at or above 10 mg/100 ml a 3 to 6 fold elevation in penicillin plasma concentration was obtained except in two instances. 2. When the para-aminohippuric acid plasma levels were allowed to fall below 10 mg/100 ml there was no effect of that compound on the plasma ...
Erna Alture-Werber   +3 more
openaire   +2 more sources

Acamprosate Is a Substrate of the Human Organic Anion Transporter (OAT) 1 without OAT3 Inhibitory Properties: Implications for Renal Acamprosate Secretion and Drug–Drug Interactions

open access: yesPharmaceutics, 2020
Acamprosate is an anionic drug substance widely used in treating symptoms of alcohol withdrawal. It was recently shown that oral acamprosate absorption is likely due to paracellular transport.
Irina E. Antonescu   +8 more
doaj   +1 more source

Investigating the interaction between organic anion transporter 1 and ochratoxin A: An in silico structural study to depict early molecular events of substrate recruitment and the impact of single point mutations [PDF]

open access: yes, 2022
Organic anion transporters (OATs) belong to a subgroup of the solute carrier 22 transporter family. OATs have a central role in xenobiotic disposition affecting the toxicokinetics of its substrates and inter-individual differences in their expression ...
Dellafiora L.   +2 more
core   +1 more source

Urinary Metabolic Biomarkers of Attentional Control in Children With Attention‐Deficit/Hyperactivity Disorder: A Dimensional Approach Through 1H NMR‐Based Metabolomics

open access: yesNMR in Biomedicine, Volume 38, Issue 8, August 2025.
This study identified five attentional control subgroups in school‐aged children, with and without ADHD, using VR‐based behavioral tests. NMR metabolomics revealed subgroup‐specific urinary metabolic profiles linked to energy and amino acid metabolism.
Ana del Mar Salmerón   +6 more
wiley   +1 more source

Iberian pig adaptation to acorn consumption: I. Net portal appearance of metabolites [PDF]

open access: yesPeerJ, 2018
Most valuable cured products from Iberian pigs come from pure bred animals raised for a final grazing-fattening period where pigs eat mainly acorns, a low protein energy rich fruit.
Ignacio Fernández-Fígares   +3 more
doaj   +2 more sources

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