Allium sativum aqueous extract prevents potassium dichromate-induced nephrotoxicity and lipid oxidation in rats [PDF]
Context: The potassium dichromate (K2Cr2O7) induces nephrotoxicity by oxidative stress mechanisms. Aims: To study the potential protection of an aqueous extract of Allium sativum against the K2Cr2O7-induced nephrotoxicity and lipid oxidation in rats ...
Sergio L. Becerra-Torres+3 more
doaj
Renal hemodynamic and morphological changes after 7 and 28 days of leptin treatment: the participation of angiotensin II via the AT1 receptor. [PDF]
The role of hyperleptinemia in cardiovascular diseases is well known; however, in the renal tissue, the exact site of leptin's action has not been established.
Karina Thieme, Maria Oliveira-Souza
doaj +1 more source
Background Type 2 diabetes causes cardio-renal complications and is treated with different combination therapies. The renal hemodynamics profile of such combination therapies has not been evaluated in detail.
Christian Ott+9 more
doaj +1 more source
Early detection of ketoprofen-induced acute kidney injury in sheep as determined by evaluation of urinary enzyme activities [PDF]
Peer ...
Honkavaara, Matti Juhana+9 more
core +1 more source
This study examined the urinary excretion of tetrodotoxin (TTX) modeled in a porcine renal proximal tubule epithelial cell line, LLC-PK1. Time course profiles of TTX excretion and reabsorption across the cell monolayers at 37 °C showed that the amount of
Takuya Matsumoto+6 more
doaj +1 more source
The Prolonging Action of Penicillin by Para-Aminohippuric Acid.
Conclusions1. When the plasma para-aminohippuric acid concentration was maintained at or above 10 mg/100 ml a 3 to 6 fold elevation in penicillin plasma concentration was obtained except in two instances. 2. When the para-aminohippuric acid plasma levels were allowed to fall below 10 mg/100 ml there was no effect of that compound on the plasma ...
Erna Alture-Werber+3 more
openaire +2 more sources
Acamprosate is an anionic drug substance widely used in treating symptoms of alcohol withdrawal. It was recently shown that oral acamprosate absorption is likely due to paracellular transport.
Irina E. Antonescu+8 more
doaj +1 more source
Investigating the interaction between organic anion transporter 1 and ochratoxin A: An in silico structural study to depict early molecular events of substrate recruitment and the impact of single point mutations [PDF]
Organic anion transporters (OATs) belong to a subgroup of the solute carrier 22 transporter family. OATs have a central role in xenobiotic disposition affecting the toxicokinetics of its substrates and inter-individual differences in their expression ...
Dellafiora L.+2 more
core +1 more source
This study identified five attentional control subgroups in school‐aged children, with and without ADHD, using VR‐based behavioral tests. NMR metabolomics revealed subgroup‐specific urinary metabolic profiles linked to energy and amino acid metabolism.
Ana del Mar Salmerón+6 more
wiley +1 more source
Iberian pig adaptation to acorn consumption: I. Net portal appearance of metabolites [PDF]
Most valuable cured products from Iberian pigs come from pure bred animals raised for a final grazing-fattening period where pigs eat mainly acorns, a low protein energy rich fruit.
Ignacio Fernández-Fígares+3 more
doaj +2 more sources