Results 1 to 10 of about 610 (113)

Pharmacokinetics ofp-Aminohippuric Acid and Inulin in Rabbits with Aristolochic Acid Nephropathy [PDF]

Advances in Pharmacological Sciences, 2011
The characteristics of aristolochic acid nephropathy (AAN) are interstitial fibrosis and atrophy of the proximal tubules, but with no change in glomeruli. To investigate the effects of AA on renal functions and the pharmacokinetics (PKs) ofp-aminohippuric acid (PAH) and inulin, New Zealand white rabbits were used in this study.
Shih-Ming Chen, Chiao-Shih Tseng, Shu-Chen Chien, Kuang-Yang Hsu   +3 more
openaire   +7 more sources

Investigating the interaction between organic anion transporter 1 and ochratoxin A: An in silico structural study to depict early molecular events of substrate recruitment and the impact of single point mutations [PDF]

, 2022
Organic anion transporters (OATs) belong to a subgroup of the solute carrier 22 transporter family. OATs have a central role in xenobiotic disposition affecting the toxicokinetics of its substrates and inter-individual differences in their expression ...
Dellafiora L., Dorne J. L. C. M., Louisse J.   +2 more
core   +4 more sources

Synthesis of novel azo compounds containing 5(4H)-oxazolone ring as potent tyrosinase inhibitors [PDF]

, 2013
Six new azo dyes containing of 5(4H)-oxazolone ring were prepared by diazotization of 4-aminohippuric acid and coupling with N,N-dimethylaniline, 1-naphthol and 2-naphthol and condensation with 4-fluoro benzaldehyde or 4-trifluoromethoxy benzaldehyde ...
Abbasalipour, V., Fozooni, S., Hamidian, H., Namjou, M., Tagizadeh, R., Taheri, A.   +5 more
core   +1 more source

Splanchnic metabolism of nutrients and hormones in steers fed alfalfa under conditions of increased absorption of ammonia and L-arginine supply across the portal-drained viscera [PDF]

, 2005
Effects of increased ammonia and/or arginine absorption on net splanchnic (portal-drained viscera [PDV] plus liver) metabolism of nonnitrogenous nutrients and hormones in cattle were examined.
Assan, Bergman, Bruggemann, C. K. Reynolds, Chalupa, D. E. Beever, Davenport, Davenport, Demigne, Elsasser, Fernandez, Gow, Hammerman, Huntington, Krebs, Kuhara, Lobley, Lobley, M. A. Lomax, Maltby, Meijer, Milano, Morgan, Newsholme, Prior, Prior, Reynolds, Reynolds, Reynolds, Reynolds, Reynolds, Reynolds, Reynolds, Reynolds, S. A. Maltby, Seal, Spires, Taniguchi, Titheradge, Tyrrell, Vicini, Visek, Waterlow   +42 more
core   +1 more source

Development and validation of an ultra-high performance liquid chromatography-tandem mass spectrometry method for the simultaneous determination of iohexol, p-aminohippuric acid and creatinine in porcine and broiler chicken plasma [PDF]

, 2019
In order to study the renal function, in terms of glomerular filtration and effective renal plasma flow, in broiler chickens and pigs, an ultra-high performance liquid chromatography-tandem mass spectrometry method for the simultaneous determination of ...
Croubels, Siska, De Baere, Siegrid, De Cock, Pieter, De Paepe, Peter, Devreese, Mathias, Dhondt, Laura   +5 more
core   +1 more source

System Identification of the Low-Dose Kinetics of p-Aminohippuric Acid [PDF]

cclm, 1995
The renal clearance of p-aminohippuric acid, due to tubular secretion in addition to glomerular filtration, can only be determined by kinetic experiments. Maximal information can be gained from observed temporal marker concentration profiles by fitting dynamic mathematical models of the processes involved, such as absorption, distribution, and ...
Estelberger, Willibald, Zitta, Sabine, Lang, Thomas, Mayer, Frank, Mauric, Astrid, Horn, Sabine, Holzer, Herwig, Petek, Walter, Reibnegger, Gilbert   +8 more
openaire   +3 more sources

Evaluation of Glycated Albumin (GA) and GA/Hba1c Ratio for Diagnosis of Diabetes and Glycemic Control: A Comprehensive Review [PDF]

, 2017
Diabetes Mellitus (DM) is a group of metabolic diseases characterized by chronic high blood glucose concentrations (hyperglycemia). When it is left untreated or improperly managed, it can lead to acute complications including diabetic ketoacidosis and ...
Abdolrahim, Mojgan, Jazayeri, Hossein E., Rabiee, Mohammad, Rajab, Asodollah, Tahriri, Mohammadreza, Tayebi, Lobat, Yazdanpanah, Sara   +6 more
core   +3 more sources

The synthesis of some acylglycines and related oxazolones [PDF]

, 1960
No description ...
Acheson, R M, Booth, D A, Brettle, R, Harris, A M   +3 more
core   +1 more source

Unraveling the contribution of fluid therapy to the development of augmented renal clearance in a piglet model [PDF]

, 2021
Augmented renal clearance (ARC) observed in the critically ill pediatric population has received an increased attention over the last years due to its major impact on the disposition and pharmacokinetics of mainly renally excreted drugs.
Croubels, Siska, De Cock, Pieter, De Paepe, Peter, Devreese, Mathias, Dhondt, Laura, Goethals, Klara   +5 more
core   +1 more source

Major role of organic anion transporter 3 in the transport of indoxyl sulfate in the kidney [PDF]

, 2002
Major role of organic anion transporter 3 in the transport of indoxyl sulfate in the kidney.BackgroundIndoxyl sulfate is a uremic toxin that accumulates in the body because of the patient's inability to excrete it and it induces a number of uremic ...
Asaba, Hiroshi, Deguchi, Tsuneo, Mori, Shinobu, Ohtsuki, Sumio, Otagiri, Masaki, Takanaga, Hitomi, Terasaki, Tetsuya   +6 more
core   +1 more source