Results 31 to 40 of about 610 (113)
Analysis of urinary exosomal metabolites identifies cardiovascular risk signatures with added value to urine analysis [PDF]
, 2020 Background: Subclinical atherosclerosis may result in fatal cardiovascular (CV) events, but the underlying mechanisms and molecular players leading to disease are not entirely understood. Thus, novel approaches capable of identifying the factors involved
Agudiez, Marta +8 more
core +2 more sources
, 2015 The organic anion transporter OAT4 (SLC22A11) and organic anion transporting polypeptide OATP2B1 (SLCO2B1) are expressed in the basal membrane of the placental syncytiotrophoblast.
Brooks, S. +6 more
core +1 more source
Interaction of Natural Dietary and Herbal Anionic Compounds and Flavonoids with Human Organic Anion Transporters 1 (SLC22A6), 3 (SLC22A8), and 4 (SLC22A11) [PDF]
, 2013 Active components of complementary/alternative medicines and natural supplements are often anionic compounds and flavonoids. As such, organic anion transporters (OATs) may play a key role in their pharmacokinetic and pharmacological profiles, and ...
Sweet, Douglas H., Wang, Li
core +3 more sources
Effects of patent foramen ovale in migraine: a metabolomics‐based study
The Journal of Physiology, Volume 603, Issue 4, Page 809-835, 15 February 2025.Abstract figure legend Aura, cystatin‐C and calcium are biomarkers of PFO in migraine. PFO closure relieves migraine by regulating 5‐HT metabolism and redox reactions, especially in the posterior head. cTTE, contrast‐transthoracic echocardiography; DESI‐MSI, desorption electrospray ionization mass imaging; H&E, haematoxylin and eosin; PFO, patent ...
Bosi Dong +15 more
wiley +1 more source
The development of a juvenile porcine augmented renal clearance model through continuous infusion of lipopolysaccharides : an exploratory study [PDF]
, 2021 Augmented renal clearance (ARC) as observed in the critically ill (pediatric) population can have a major impact on the pharmacokinetics and posology of renally excreted drugs.
Croubels, Siska +7 more
core +1 more source
Physiological Reports, Volume 13, Issue 1, January 2025.Abstract Sepsis leads to an acute breakdown of muscle to support increased caloric and amino acid requirements. Little is known about the role of adipose and muscle tissue breakdown and intestinal metabolism in glucose substrate supply during the acute phase of sepsis.
Ryan Morse +6 more
wiley +1 more source
A Statistically Rigorous Test for the Identification of Parent−Fragment Pairs in LC-MS Datasets [PDF]
, 2010 Untargeted global metabolic profiling by liquid chromato-graphy−mass spectrometry generates numerous signals that are due to unknown compounds and whose identification forms an important challenge.
Chakraborty A. +23 more
core +2 more sources
Journal of Food Science, Volume 89, Issue 12, Page 10134-10151, December 2024.Abstract Olive oil polyphenol hydroxytyrosol (HT) significantly repairs intestinal barrier function, but its absorption in the stomach and small intestine is limited. The metabolites of unabsorbed HT that reach the colon are crucial, yet their effects on colonic microbiota and intestinal barrier repair remain unclear.
Yuqing Song +7 more
wiley +1 more source
Active Mammary Excretion of N4-Acetylated p-Aminohippuric Acid*) [PDF]
Acta Veterinaria Scandinavica, 1969 Different excretion patterns were observed for p-amino- hippuric acid and its acetylated metabolite in mammary excretion experiments in goats and cows. The excretion of p-aminohippuric acid conformed to passive diffusion of the non-protein bound and un-ionized fraction (Rasmussen 1958, 1966) as described by Miller et al. (1967).
openaire +3 more sources
Features, Causes and Consequences of Splanchnic Sequestration of Amino Acid in Old Rats [PDF]
, 2011 RATIONALE: In elderly subjects, splanchnic extraction of amino acids (AA) increases during meals in a process known as splanchnic sequestration of amino acids (SSAA).
A Tourianyjf +58 more
core +3 more sources