Results 41 to 50 of about 1,689 (203)
Evaluation of p-aminohippurate as a marker for blood-flow determinations in cattle [PDF]
P-aminohippurate (PAH) was evaluated as a potential blood-flow marker in steers for use in trans-organ balance studies. Because of problems in methods available for PAH determination, a high pressure liquid chromatography (HPLC) procedure was developed ...
Meerdink, Denis Jay
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Abstract Purpose Reliable information about renal blood supply is important to understand kidney physiology and diseases. Arterial spin labeling MR (ASL‐MR) imaging and [15O]H2O positron emission tomography (PET) can noninvasively measure tissue perfusion but have never been directly compared.
Naja Enevold Olsen +9 more
wiley +1 more source
Hippurate: the natural history of a mammalian-microbial co-metabolite [PDF]
Hippurate, the glycine conjugate of benzoic acid, is a normal constituent of the endogenous urinary metabolite profile and has long been associated with the microbial degradation of certain dietary components, hepatic function and toluene exposure, and ...
Holmes, Elaine +4 more
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The Concise Guide to PHARMACOLOGY 2025/26: Transporters
The Concise Guide to Pharmacology 2025/26 marks the seventh edition in this series of biennial publications in the British Journal of Pharmacology. Presented in landscape format, the guide provides a comparative overview of the pharmacology of drug target families. The concise nature of the Concise Guide refers to the style of presentation, being clear,
Stephen P. H. Alexander +28 more
wiley +1 more source
This study identified five attentional control subgroups in school‐aged children, with and without ADHD, using VR‐based behavioral tests. NMR metabolomics revealed subgroup‐specific urinary metabolic profiles linked to energy and amino acid metabolism.
Ana del Mar Salmerón +6 more
wiley +1 more source
Dendrimers and derivatives as a potential therapeutic tool in regenerative medicine strategies : a review [PDF]
Since the pioneering work dealing with the synthesis and physicochemical aspects of dendrimers, a predictable and tunable set of compositions for therapeutic, scaffolding and imaging systems has been reported.
Mano, J. F. +4 more
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Inulin and para-aminohippuric acid: determinants of glomerular filtration rate and renal blood flow following single intravenous bolus injection in man [PDF]
McAuslane, James Alastair Neil
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ABSTRACT Dersimelagon is a novel investigational orally administered selective agonist of the melanocortin‐1 receptor. The drug–drug interaction (DDI) potential of dersimelagon was investigated in both nonclinical (in vitro) and clinical studies. The in vitro inhibition of CYP/UGT isoforms and efflux/uptake transporters by dersimelagon was assessed ...
Akihito Ogasawara +4 more
wiley +1 more source
Effects of patent foramen ovale in migraine: a metabolomics‐based study
Abstract figure legend Aura, cystatin‐C and calcium are biomarkers of PFO in migraine. PFO closure relieves migraine by regulating 5‐HT metabolism and redox reactions, especially in the posterior head. cTTE, contrast‐transthoracic echocardiography; DESI‐MSI, desorption electrospray ionization mass imaging; H&E, haematoxylin and eosin; PFO, patent ...
Bosi Dong +15 more
wiley +1 more source
Cardiac mitochondria were isolated from Bufo marinus and Rana catesbeiana, two species of amphibian whose cardiovascular systems are adapted to either predominantly aerobic or glycolytic modes of locomotion.
Duerr, Jeff, Tucker, Kristina
core +1 more source

