Results 41 to 50 of about 1,689 (203)

Evaluation of p-aminohippurate as a marker for blood-flow determinations in cattle [PDF]

open access: yes, 1981
P-aminohippurate (PAH) was evaluated as a potential blood-flow marker in steers for use in trans-organ balance studies. Because of problems in methods available for PAH determination, a high pressure liquid chromatography (HPLC) procedure was developed ...
Meerdink, Denis Jay
core   +2 more sources

Measurement of renal cortex perfusion: A direct comparison of arterial spin labelling magnetic resonance imaging and [15O]H2O positron emission tomography

open access: yesMagnetic Resonance in Medicine, Volume 94, Issue 6, Page 2537-2549, December 2025.
Abstract Purpose Reliable information about renal blood supply is important to understand kidney physiology and diseases. Arterial spin labeling MR (ASL‐MR) imaging and [15O]H2O positron emission tomography (PET) can noninvasively measure tissue perfusion but have never been directly compared.
Naja Enevold Olsen   +9 more
wiley   +1 more source

Hippurate: the natural history of a mammalian-microbial co-metabolite [PDF]

open access: yes, 2013
Hippurate, the glycine conjugate of benzoic acid, is a normal constituent of the endogenous urinary metabolite profile and has long been associated with the microbial degradation of certain dietary components, hepatic function and toluene exposure, and ...
Holmes, Elaine   +4 more
core   +1 more source

The Concise Guide to PHARMACOLOGY 2025/26: Transporters

open access: yesBritish Journal of Pharmacology, Volume 182, Issue S1, Page S404-S496, December 2025.
The Concise Guide to Pharmacology 2025/26 marks the seventh edition in this series of biennial publications in the British Journal of Pharmacology. Presented in landscape format, the guide provides a comparative overview of the pharmacology of drug target families. The concise nature of the Concise Guide refers to the style of presentation, being clear,
Stephen P. H. Alexander   +28 more
wiley   +1 more source

Urinary Metabolic Biomarkers of Attentional Control in Children With Attention‐Deficit/Hyperactivity Disorder: A Dimensional Approach Through 1H NMR‐Based Metabolomics

open access: yesNMR in Biomedicine, Volume 38, Issue 8, August 2025.
This study identified five attentional control subgroups in school‐aged children, with and without ADHD, using VR‐based behavioral tests. NMR metabolomics revealed subgroup‐specific urinary metabolic profiles linked to energy and amino acid metabolism.
Ana del Mar Salmerón   +6 more
wiley   +1 more source

Dendrimers and derivatives as a potential therapeutic tool in regenerative medicine strategies : a review [PDF]

open access: yes, 2010
Since the pioneering work dealing with the synthesis and physicochemical aspects of dendrimers, a predictable and tunable set of compositions for therapeutic, scaffolding and imaging systems has been reported.
Mano, J. F.   +4 more
core   +1 more source

Assessment of Potential Drug–Drug Interactions for Novel Oral Melanocortin‐1 Receptor Agonist Dersimelagon

open access: yesPharmacology Research &Perspectives, Volume 13, Issue 1, February 2025.
ABSTRACT Dersimelagon is a novel investigational orally administered selective agonist of the melanocortin‐1 receptor. The drug–drug interaction (DDI) potential of dersimelagon was investigated in both nonclinical (in vitro) and clinical studies. The in vitro inhibition of CYP/UGT isoforms and efflux/uptake transporters by dersimelagon was assessed ...
Akihito Ogasawara   +4 more
wiley   +1 more source

Effects of patent foramen ovale in migraine: a metabolomics‐based study

open access: yesThe Journal of Physiology, Volume 603, Issue 4, Page 809-835, 15 February 2025.
Abstract figure legend Aura, cystatin‐C and calcium are biomarkers of PFO in migraine. PFO closure relieves migraine by regulating 5‐HT metabolism and redox reactions, especially in the posterior head. cTTE, contrast‐transthoracic echocardiography; DESI‐MSI, desorption electrospray ionization mass imaging; H&E, haematoxylin and eosin; PFO, patent ...
Bosi Dong   +15 more
wiley   +1 more source

Pyruvate Transport in Isolated Cardiac Mitochondria from two Species of Amphibian Exhibiting Dissimilar Aerobic Scope: Bufo Marinus and Rana Catesbeiana

open access: yes, 2007
Cardiac mitochondria were isolated from Bufo marinus and Rana catesbeiana, two species of amphibian whose cardiovascular systems are adapted to either predominantly aerobic or glycolytic modes of locomotion.
Duerr, Jeff, Tucker, Kristina
core   +1 more source

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