Results 41 to 50 of about 860 (163)

Concurrent Preimplantation Genetic Testing and Competence Assessment of Human Embryos by Transcriptome Sequencing

Advanced Science, Volume 11, Issue 32, August 27, 2024.
The accuracy and applicability of routine preimplantation genetic testing (PGT) is confounded by uneven genome coverage and a high allele drop‐out rate from single‐cell whole genome amplification. This study proposes an alternative method to PGT by leveraging the abundant mRNA transcript copies present in trophectoderm cells to accurately diagnose ...
Yuqian Wang, Ye Li, Xiaohui Zhu, Ming Yang, Yujun Liu, Nan Wang, Chuan Long, Ying Kuo, Ying Lian, Jin Huang, Jialin Jia, Catherine C. L. Wong, Zhiqiang Yan, Liying Yan, Jie Qiao   +14 more
wiley   +1 more source

Biochemical Characterization of Kluyveromyces lactis Adenine Deaminase and Guanine Deaminase and Their Potential Application in Lowering Purine Content in Beer [PDF]

, 2018
Excess amounts of uric acid in humans leads to hyperuricemia, which is a biochemical precursor of gout and is also associated with various other disorders. Gout is termed as crystallization of uric acid, predominantly within joints.
Durga Mahor, Gandham S. Prasad
core   +2 more sources

Geographical distribution and molecular insights into abamectin and milbemectin cross-resistance in European field populations of Tetranychus urticae [PDF]

, 2020
BACKGROUND Milbemectin and abamectin are frequently used to control the spider mite Tetranychus urticae. The development of abamectin resistance in this major pest has become an increasing problem worldwide, potentially compromising the use of ...
Dermauw, Wannes, İnak, Emre, Njiru, Christine, Snoeck, Simon, Van Leeuwen, Thomas, Xue, Wenxin   +5 more
core   +1 more source

Safety evaluation of an extension of use of the food enzyme glutaminase from the non‐genetically modified Bacillus amyloliquefaciens strain AE‐GT

EFSA Journal, Volume 22, Issue 7, July 2024.
Abstract The food enzyme glutaminase (l‐glutamine amidohydrolase; EC 3.5.1.2) is produced with the non‐genetically modified Bacillus amyloliquefaciens strain AE‐GT by Amano Enzyme Inc. A safety evaluation of this food enzyme was made previously, in which EFSA concluded that this food enzyme did not give rise to safety concerns when used in five food ...
EFSA Panel on Food Contact Materials, Enzymes and Processing Aids (CEP), Claude Lambré, José Manuel Barat Baviera, Claudia Bolognesi, Pier Sandro Cocconcelli, Riccardo Crebelli, David Michael Gott, Konrad Grob, Evgenia Lampi, Marcel Mengelers, Alicja Mortensen, Gilles Rivière, Inger‐Lise Steffensen, Christina Tlustos, Henk Van Loveren, Laurence Vernis, Holger Zorn, Yrjö Roos, Daniele Cavanna, Yi Liu, Giulio di Piazza, Andrew Chesson   +22 more
wiley   +1 more source

Safety evaluation of the food enzyme glutaminase from the genetically modified Bacillus licheniformis strain NZYM‐JQ

EFSA Journal, Volume 22, Issue 4, April 2024.
Abstract The food enzyme glutaminase (l‐glutamine amidohydrolase EC 3.5.1.2) is produced with the genetically modified Bacillus licheniformis strain NZYM‐JQ by Novozymes A/S. The genetic modifications do not give rise to safety concerns. The production strain met the requirements for the qualified presumption of safety (QPS).
EFSA Panel on Food Contact Materials, Enzymes and Processing Aids (CEP), Claude Lambré, José Manuel Barat Baviera, Claudia Bolognesi, Pier Sandro Cocconcelli, Riccardo Crebelli, David Michael Gott, Konrad Grob, Evgenia Lampi, Marcel Mengelers, Alicja Mortensen, Gilles Rivière, Inger‐Lise Steffensen, Christina Tlustos, Henk Van Loveren, Laurence Vernis, Holger Zorn, Yrjö Roos, Magdalena Andryszkiewicz, Ana Criado, Ana Gomes, Yi Liu, Daniele Cavanna, Giulio di Piazza, Andrew Chesson   +25 more
wiley   +1 more source

Safety evaluation of the food enzyme AMP deaminase from non‐genetically modified Aspergillus sp. strain DEA 56‐111

EFSA Journal, Volume 22, Issue 4, April 2024.
Abstract The food enzyme AMP deaminase (AMP aminohydrolase; EC 3.5.4.6) is produced with the non‐genetically modified microorganism Aspergillus sp. strain DEA 56‐111 by Shin Nihon Chemical Co., Ltd. The food enzyme was considered free from viable cells of the production organism.
EFSA Panel on Food Contact Materials, Enzymes and Processing Aids (CEP), Claude Lambré, José Manuel Barat Baviera, Claudia Bolognesi, Pier Sandro Cocconcelli, Riccardo Crebelli, David Michael Gott, Konrad Grob, Evgenia Lampi, Marcel Mengelers, Alicja Mortensen, Gilles Rivière, Inger‐Lise Steffensen, Christina Tlustos, Henk Van Loveren, Laurence Vernis, Holger Zorn, Lieve Herman, Yrjö Roos, Magdalena Andryszkiewicz, Daniele Cavanna, Natália Kovalkovičová, Yi Liu, Simone Lunardi, Andrew Chesson   +25 more
wiley   +1 more source

The role of glutamate and glutamine metabolism and related transporters in nerve cells

CNS Neuroscience &Therapeutics, Volume 30, Issue 2, February 2024.
The glutamate (Glu)‐glutamine (Gln) cycle between neurons and astrocytes, facilitated by cell surface transporters, plays a pivotal role in regulating synaptic glutamate levels, thereby influencing excitatory transmission. Moreover, glutamate serves as a carbon donor to generate α‐ketoglutarate (α‐KG), acts as a nitrogen donor for the synthesis of non ...
Dongyang Zhang, Zhongyan Hua, Zhijie Li
wiley   +1 more source

Safety evaluation of the food enzyme glutaminase from the non‐genetically modified Bacillus amyloliquefaciens strain AE‐GT

EFSA Journal, Volume 22, Issue 2, February 2024.
Abstract The food enzyme glutaminase (l‐glutamine amidohydrolase; EC 3.5.1.2) is produced with the non‐genetically modified Bacillus amyloliquefaciens strain AE‐GT by Amano Enzyme Inc. The production strain met the requirements for the qualified presumption of safety (QPS) approach.
EFSA Panel on Food Contact Materials, Enzymes and Processing Aids (CEP), Vittorio Silano, José Manuel Barat Baviera, Claudia Bolognesi, Pier Sandro Cocconcelli, Riccardo Crebelli, David Michael Gott, Konrad Grob, Claude Lambré, Evgenia Lampi, Marcel Mengelers, Alicja Mortensen, Gilles Rivière, Inger‐Lise Steffensen, Christina Tlustos, Henk Van Loveren, Laurence Vernis, Holger Zorn, Magdalena Andryszkiewicz, Daniele Cavanna, Yi Liu, Simone Lunardi, Elsa Nielsen, Karin Norby, Giulio di Piazza, Yrjö Roos, Andrew Chesson   +27 more
wiley   +1 more source

Cell Death Pathway Regulation by Functional Nanomedicines for Robust Antitumor Immunity

Advanced Science, Volume 11, Issue 3, January 19, 2024.
This review provides a comprehensive overview of the nanotechnology assisted PCD routes resulting in antitumor immunity including ferroptosis, pyroptosis, autophagy, necroptosis, apoptosis and cuproptosis, systematically introduces their therapeutic mechanisms, nanocarrier types as well as immune cell types, highlights the challenges and perspectives ...
Yongjuan Li, Yichen Guo, Kaixin Zhang, Rongrong Zhu, Xiaoyuan Chen, Zhenzhong Zhang, Weijing Yang   +6 more
wiley   +1 more source

Synthesis of Purines by Inverse Electron Demand Diels-Alder Reactions of Amines with 1,3,5-Triazines and of Fluorinated Arenes by Palladium(0)-Catalyzed Cross-Coupling Reactions and Photophysical Properties of the Products [PDF]

, 2011
The formal inverse electron demand Diels-Alder reactions of amines with 1,3,5-triazine and 2,4,6-tris(trifluoromethyl)-1,3,5-triazine provided functionalized purines and bi-purines.
Maalik, Aneela (gnd: 1018497382)
core   +1 more source