Deletion of TSPO resulted in change of metabolomic profile in retinal pigment epithelial cells [PDF]
, 2019 Age-related macular degeneration is the main cause of vision loss in the aged population worldwide. Drusen, extracellular lesions formed underneath the retinal pigment epithelial (RPE) cells, are a clinical feature of AMD and associated with AMD ...
Abdulwahab Alamri +7 more
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A Novel Pathway for Metabolism of the Cardiovascular Risk Factor Homoarginine by alanine:glyoxylate aminotransferase 2 [PDF]
, 2016 Low plasma concentrations of L-homoarginine are associated with an increased risk of cardiovascular events, while homoarginine supplementation is protective in animal models of metabolic syndrome and stroke.
Bode-Böger, SM +12 more
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Conformational photoswitching of a synthetic peptide foldamer bound within a phospholipid bilayer [PDF]
, 2016 The dynamic properties of foldamers, synthetic molecules that mimic folded biomolecules, have mainly been explored in free solution.We report on the design, synthesis, and conformational behavior of photoresponsive foldamers bound in a phospholipid ...
Clayden, Jonathan +5 more
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Skeletal muscles and gut microbiota-derived metabolites: novel modulators of adipocyte thermogenesis
Frontiers in Endocrinology, 2023 Obesity occurs when overall energy intake surpasses energy expenditure. White adipose tissue is an energy storage site, whereas brown and beige adipose tissues catabolize stored energy to generate heat, which protects against obesity and obesity ...
Yi Tang +5 more
doaj +1 more source
Promising approaches to optimize the biological properties of the antimicrobial peptide esculentin-1a(1-21)NH2. amino acids substitution and conjugation to nanoparticles [PDF]
, 2017 Antimicrobial peptides (AMPs) represent an interesting class of molecules with expanding biological properties which make them a viable alternative for the development of future antibiotic drugs.
Cacciafesta, Mauro +3 more
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Effects of water deficit during maturation on amino acids and jujube fruit eating quality
Macedonian Journal of Chemistry and Chemical Engineering, 2014 Pear-jujube yield and fruit characteristics can be clearly modified by a water deficit imposed during fruit maturation period. One essential (cystine (Cys-cys)) and seven non-essential (4-hydroxyproline (p-Hyp), α-aminoadipic acid (AADA), ornithine ...
Jacinta Collado-González +10 more
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Targeting Hormone-Related Pathways to Improve Grain Yield in Rice: A Chemical Approach.
PLoS ONE, 2015 Sink/source relationships, regulating the mobilization of stored carbohydrates from the vegetative tissues to the grains, are of key importance for grain filling and grain yield.
Hiroaki Tamaki +5 more
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Crystal structure and hydrogen bonding in N-(1-deoxy-β-d-fructopyranos-1-yl)-2-aminoisobutyric acid
Acta Crystallographica Section E: Crystallographic Communications, 2018 The title compound, alternatively called d-fructose-2-aminoisobutyric acid (FruAib), C10H19NO7, (I), crystallizes exclusively in the β-pyranose form, with two conformationally non-equivalent molecules [(IA) and (IB)] in the asymmetric unit.
Valeri V. Mossine +2 more
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^|^alpha;-Aminoisobutyric Acid as the Constituent Amino Acid of Protein
Agricultural and Biological Chemistry, 1961 Makoto KANDATSU, Keiichiro KIKUNO
openaire +3 more sources
Cloning, expression, and localization of a rat brain high-affinity glycine transporter [PDF]
, 1992 A cDNA clone encoding a glycine transporter has been isolated from rat brain by a combined PCR and plaque-hybridization strategy. mRNA synthesized from this clone (designated GLYT1) directs the expression of sodium-and chloride-dependent, high-affinity ...
Brecha, Nicholas +4 more
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