Results 81 to 90 of about 9,324 (253)
The Journal of Physiology, Volume 604, Issue 6, Page 2458-2472, 15 March 2026.Abstract figure legend A schematic diagram outlining the concept of enviromimetics, and the subclasses of exercise mimetics, epimimetics and cognitomimetics. The rationale is that environmental stimulation and lifestyle factors, including physical activity and cognitive stimulation, have shown beneficial effects across a range of human conditions ...
Anthony J. Hannan
wiley +1 more source
The FASEB Journal, Volume 40, Issue 4, 28 February 2026.Postmenopausal osteoporosis (PMOP) is increasingly recognized as an aging‐associated, multisystem state of fragility, in which estrogen deficiency exacerbates immune and metabolic drift across the bone marrow, skeletal muscle, adipose tissue, gut, vascular system, and neural circuits.
Xianlin Rao, Xiaoyu Cai
wiley +1 more source
Strategies to Improve the Lipophilicity of Hydrophilic Macromolecular Drugs
Advanced Healthcare Materials, Volume 15, Issue 5, 2 February 2026.Hydrophilic macromolecular drugs can be successfully lipidized by covalent attachment of lipids, by hydrophobic ion pairing with negatively or positively charged surfactants, and by dry or wet reverse micelle formation. Lipophilicity enhancement of hydrophilic macromolecules has several benefits including stability and bioavailability improvement ...
Sera Lindner +8 more
wiley +1 more source
Cumhuriyet Science JournalMultiple sclerosis (MS) is a neuroinflammatory disease associated with involving metabolic disruptions. Although amino acid metabolism is linked to MS pathophysiology, its role remains unclear.
Sümeyra Kaplan +4 more
doaj +1 more source
Potential Roles of Exercise-Induced Plasma Metabolites Linking Exercise to Health Benefits
Frontiers in Physiology, 2020 Regular exercise has a myriad of health benefits. An increase in circulating exercise factors following exercise is a critical physiological response. Numerous studies have shown that exercise factors released from tissues during physical activity may ...
Yong Ryoul Yang +2 more
doaj +1 more source
Genetic transformation of Fusarium avenaceum by Agrobacterium tumefaciens mediated transformation and the development of a USER-Brick vector construction system [PDF]
, 2014 BACKGROUND: The plant pathogenic and saprophytic fungus Fusarium avenaceum causes considerable in-field and post-field losses worldwide due to its infections of a wide range of different crops.
Frandsen, Rasmus John Normand +5 more
core +2 more sources
ChemistrySelect, Volume 11, Issue 6, 12 February 2026.The Seplife Fmoc‐RinkAmide‐PS‐PEG resin, a PEG‐grafted PS resin with optimized composition enables improved swelling and higher loading for SPPS. This resin delivers efficient couplings and high crude purities, supporting reliable synthesis of long and complex peptides.
Ashish Kumar +12 more
wiley +1 more source
Metabolomic analysis of serum from rats following long-term intake of Chinese sausage
Food & Nutrition Research, 2018 Introduction: Owing to the contamination of chemical pollutants, especially nitrosamines and their precursors, in Chinese sausage, long-term intake of Chinese sausage may have potential health effects.
Minxian Rong +5 more
doaj +1 more source
A metabolic comparison of GIPR agonism versus GIPR antagonism in male mice
Diabetes, Obesity and Metabolism, Volume 28, Issue 2, Page 1160-1167, February 2026.Abstract Aims Targeting the glucose dependent insulinotropic polypeptide receptor (GIPR) is of growing interest for treating type 2 diabetes and obesity, though the optimal approach remains unclear. Both GIPR agonism and antagonism, respectively, incorporated into drugs like tirzepatide and maridebart cafraglutide, have paradoxically both shown ...
Iona Davies +11 more
wiley +1 more source
Influence of Drying Method on NMR-Based Metabolic Profiling of Human Cell Lines
Metabolites, 2019 Metabolic profiling of cell line and tissue extracts involves sample processing that includes a drying step prior to re-dissolving the cell or tissue extracts in a buffer for analysis by GC/LC-MS or NMR.
Irina Petrova +4 more
doaj +1 more source