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Physiologically Based Pharmacokinetic Modeling of Elexacaftor/Tezacaftor/Ivacaftor in Infants With Cystic Fibrosis. [PDF]
CPT Pharmacometrics Syst PharmacolTruong NH +16 more
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Ready N-alkylation of enantiopure aminophenols: synthesis of tertiary aminophenols
Tetrahedron, 2001Abstract A regioselective indirect alkylation of aminophenols to enantiopure tertiary aminophenols, which are useful chiral ligands for metal-catalysed asymmetric reactions, is reported. This very simple synthetic methodology, through reduction or alkylation of an intermediate benzoxazine, was performed in mild conditions, suitable for the ...
Cristina Cimarelli +2 more
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Mendeleev Communications, 2020
An efficient atom-economic chemoselective synthesis of vinyloxyanilines from aminophenols and acetylene catalyzed by sodium aminophenolates in aqueous DMSO (90 °C, 3 h) has been developed.
Ludmila A Oparina +2 more
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An efficient atom-economic chemoselective synthesis of vinyloxyanilines from aminophenols and acetylene catalyzed by sodium aminophenolates in aqueous DMSO (90 °C, 3 h) has been developed.
Ludmila A Oparina +2 more
exaly +2 more sources
Journal of the Chemical Society C: Organic, 1966
o-Aminophenol gave, on tritylation under various sets of conditions, 2-amino-5-tritylphenol (I), this structure being different from the one assigned in an earlier report. m-Aminophenol and m-anisidine yielded 5-amino-2-tritylphenol (V) and 3-methoxy-4-tritylaniline (VIII), respectively, p-Aminophenol and p-anisidine were not tritylated under the same ...
Gabriel Chuchani, Jacob Zabicky
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o-Aminophenol gave, on tritylation under various sets of conditions, 2-amino-5-tritylphenol (I), this structure being different from the one assigned in an earlier report. m-Aminophenol and m-anisidine yielded 5-amino-2-tritylphenol (V) and 3-methoxy-4-tritylaniline (VIII), respectively, p-Aminophenol and p-anisidine were not tritylated under the same ...
Gabriel Chuchani, Jacob Zabicky
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The Metabolism of Aminophenols in Erythrocytes
Xenobiotica, 19881. Like 2- and 4-dimethylaminophenol, 4-aminophenol in the presence of oxyhaemoglobin forms numerous adducts with glutathione (GSH). Using 14C-4-aminophenol and 3H-glutathione, ten different thioethers were isolated, by h.p.l.c., with isotope ratios of 1:1, 1:2, 1:3, respectively.
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Development by Aminophenols II
The Journal of Photographic Science, 1977AbstractIn general, the rate of development by aminophenols at a given pH is proportional to their concentration. When the concentration is held constant and the pH is varied, the aminophenols divide into two groups. In one, the rate is proportional to the calculated concentration of the relevant ion species, whereas in the other, the rate varies as ...
J.R. Fyson, J.R. Levenson
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Microdetermination ofp-aminophenol
Mikrochimica Acta, 1961A colorimetric method for the miorodetermination ofp-aminophenol based on indophenol dye formation is described. The conditions for its determination in the presence of theo- andm-isomers are given.
Ervin Jungreis, Jacques C. Soriano
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Solid State Sciences, 2009
Abstract Three new hybrid crystals of 2-aminophenol-HClO4 (2-AP-HClO4, 1), 3-aminophenol-HClO4 (3-AP-HClO4, 2) and 4-aminophenol-HClO4 (4-AP-HClO4, 3) were obtained and their crystal structures determined. The 1 crystallises in centrosymmetric space group C2/c of monoclinic system while the other two (2 and 3) crystallise in the non-centro symmetric ...
Jan Janczak, Genivaldo Julio Perpétuo
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Abstract Three new hybrid crystals of 2-aminophenol-HClO4 (2-AP-HClO4, 1), 3-aminophenol-HClO4 (3-AP-HClO4, 2) and 4-aminophenol-HClO4 (4-AP-HClO4, 3) were obtained and their crystal structures determined. The 1 crystallises in centrosymmetric space group C2/c of monoclinic system while the other two (2 and 3) crystallise in the non-centro symmetric ...
Jan Janczak, Genivaldo Julio Perpétuo
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Effect of p-aminophenols on tyrosinase activity
Bioorganic & Medicinal Chemistry, 2014Tyrosinase is involved in the synthesis of melanin in the skin and hair as well as neuromelanin in the brain. This rate limiting enzyme catalyzes two critical steps (reactions) in melanogenesis; the hydroxylation of tyrosine to form DOPA and the subsequent oxidation of DOPA into dopaquinone.
Yu, Komori +4 more
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