Results 1 to 10 of about 8,542 (209)

Early aminophylline is a potential therapy for preventing bronchopulmonary dysplasia in premature infants: a retrospective study [PDF]

BMC Pediatrics
Background Aminophylline is commonly used to treat apnea in premature infants. However, its impact on long-term complications in preterm infants is unclear.This retrospective study aimed to evaluate the effects and safety of early aminophylline in ...
Lijun Tang, Qiqiong Wang, Linmei Jiang, Si Chen, Weibin Wu, Guangliang Bi   +5 more
doaj   +3 more sources

Aminophylline in acute exacerbation of COPD: Utility and treatment effects in hypercapnic respiratory failure (ACUTE): A pilot observational study [PDF]

Lung India
Background and Objective: Aminophylline may play a role in managing both stable and exacerbating COPD, but its use is controversial due to its narrow therapeutic window.
Amrita Bhattacharyya, Raja Dhar, Shyam Krishnan, Arup Halder, Beauty Biswas, Aditya Satpati, Ishita Chattopadhyay   +6 more
doaj   +2 more sources

Adjunctive sepsis therapy with aminophylline (STAP): a randomized controlled trial

Chinese Medical Journal, 2022
. Background:. Sepsis is a serious disease caused by infection. Aminophylline has anti-asthma and anti-inflammatory effects. We aimed to explore the safety and effect of aminophylline in sepsis. Methods:.
Ruifang Zhang, Huan Liu, Dongmei Dai, Xianfei Ding, Dong Wang, Yan Wang, Xuexiu Shi, Shuguang Zhang, Xiaoguang Duan, Haixu Wang, Yonggang Luo, Shaohua Liu, Bing Han, Xiaojuan Zhang, Yu Fang, Jing Yang, Wangbin Xu, Tongwen Sun, Yanjie Yin   +18 more
doaj   +2 more sources

Efficacy of nebulised dexmedetomidine versus aminophylline for treatment of postdural puncture headache in patients undergoing subarachnoid block posted for caesarean section: a double-blind, randomised controlled study [PDF]

BMJ Neurology Open
Background Postdural puncture headache (PDPH) following spinal anaesthesia significantly affects postpartum recovery. We evaluated the efficacy of nebulised dexmedetomidine and aminophylline in women with moderate to severe PDPH after caesarean delivery ...
Neeraj Kumar, Alok Ranjan, Monika Anant, Abhyuday Kumar, R K V Kavya   +4 more
doaj   +2 more sources

Salbutamol attenuates arrhythmogenic effect of aminophylline in a hPSC-derived cardiac model [PDF]

Scientific Reports
The combination of aminophylline and salbutamol is frequently used in clinical practice in the treatment of obstructive lung diseases. While the side effects (including arrhythmias) of the individual bronchodilator drugs were well described previously ...
Daniil Kabanov, Simon Vrana Klimovic, Deborah Beckerová, Martin Molcan, Martin Scurek, Kristian Brat, Marketa Bebarova, Vladimir Rotrekl, Jan Pribyl, Martin Pesl   +9 more
doaj   +2 more sources

A randomised feasibility tolerability study of aminophylline for the prevention of preterm labour [PDF]

BMC Pregnancy and Childbirth
Background Progesterone is known to maintain uterine quiescence as pregnancy advances. Recently, its efficacy in preventing preterm birth has been questioned prompting a search for an alternative treatment option. Cyclic AMP has been shown invitro to act
Natasha Singh, Nishel Mohan Shah, Gavin Sooranna, Miriam Bourke, Angela Yulia, Cheryl Battersby, Rachel M. Tribe, Mark R. Johnson   +7 more
doaj   +2 more sources

Aminophylline Induces Two Types of Arrhythmic Events in Human Pluripotent Stem Cell–Derived Cardiomyocytes

Frontiers in Pharmacology, 2022
Cardiac side effects of some pulmonary drugs are observed in clinical practice. Aminophylline, a methylxanthine bronchodilator with documented proarrhythmic action, may serve as an example.
Simon Klimovic, Simon Klimovic, Simon Klimovic, Martin Scurek, Martin Scurek, Martin Pesl, Martin Pesl, Martin Pesl, Deborah Beckerova, Deborah Beckerova, Sarka Jelinkova, Tomas Urban, Tomas Urban, Daniil Kabanov, Daniil Kabanov, Daniil Kabanov, Zdenek Starek, Zdenek Starek, Marketa Bebarova, Jan Pribyl, Vladimir Rotrekl, Vladimir Rotrekl, Kristian Brat, Kristian Brat, Kristian Brat   +24 more
doaj   +1 more source

Specific Premature Groups Have Better Benefits When Treating Apnea With Caffeine Than Aminophylline/Theophylline

Frontiers in Pediatrics, 2022
BackgroundMethylxanthines (caffeine; aminophylline/theophylline) are commonly used for apnea of prematurity (AOP) treatment. We aimed to compare the efficacy and adverse effects of caffeine and aminophylline/theophylline.MethodsA retrospective case ...
Yi-Chieh Lin, Yi-Chieh Lin, Yin-Ling Tan, Ting-An Yen, Chien-Yi Chen, Po-Nien Tsao, Hung-Chieh Chou   +6 more
doaj   +1 more source

Effects of early aminophylline therapy on clinical outcomes in premature infants

Pediatrics and Neonatology, 2023
Background: Aminophylline use and the association between clinical outcomes and therapy timing have been less investigated. The objective of this study was to determine the efficacy of early aminophylline use (within the first two days of life) in ...
Yi-Ting Chu, Jin-Shuen Chen, Yao-Shen Chen, Chih-Chieh Yang, Chun-Hao Yin, Hsiao-Ping Wang, Yee-Hsuan Chiou   +6 more
doaj   +1 more source

Comparative efficacy and safety of caffeine citrate and aminophylline in treating apnea of prematurity: A systematic review and meta-analysis.

PLoS ONE, 2022
BackgroundMethylxanthine, including caffeine citrate and aminophylline, is the most common pharmacologic treatment for apnea of prematurity. However, due to the lack of high-quality evidence, there are no clear recommendations or guidelines on how to ...
Yiqun Miao, Yun Zhou, Shuliang Zhao, Wenwen Liu, Aihua Wang, Yuanyuan Zhang, Yanan Li, Huimin Jiang   +7 more
doaj   +2 more sources