Results 121 to 130 of about 56,967 (294)

Drug Survival of Drugs Recommended for Irritable Bowel Syndrome: A Retrospective Observational Study

open access: yesNeurogastroenterology &Motility, EarlyView.
ABSTRACT Background There is limited data on how drugs prescribed for functional bowel disorders are re‐prescribed in clinical practice. This study aimed to investigate drug survival rates of different irritable bowel syndrome (IBS) treatments among patients referred to a gastroenterologist.
Alice Sandberg‐Janzon, Pontus Karling
wiley   +1 more source

Delphi Consensus Among French Obesity Experts on Clinical Recommendations for Drug Prescription in Patients With Severe Obesity

open access: yesObesity Reviews, EarlyView.
ABSTRACT Introduction Although the physiologic alterations seen in obesity often affect the pharmacokinetics and pharmacodynamics of drugs, most clinical trials do not consider these aspects specifically for this population. To date, there is no list of potentially inappropriate medications for patients living with obesity. The aim of this study was to
Sarah Berdot   +17 more
wiley   +1 more source

Use of amitriptyline for the treatment of chronic tension-type headache : review of the literature [PDF]

open access: yes, 2008
Amitriptyline is a tricyclic antidepressant, considered the treatment of choice for different types of chronic pain, including chronic myofascial pain. Its antinociceptive property is independent of its antidepressant effect.
Gay Escoda, Cosme   +2 more
core  

The Genetic Blueprint of Obesity: From Pathogenesis to Novel Therapies

open access: yesObesity Reviews, EarlyView.
ABSTRACT Obesity is a chronic metabolic disease characterized by disturbances in energy homeostasis, leading to excessive fat accumulation. The pathogenesis of the disease is shaped by a complex interplay of genetic, epigenetic, biological, psychological, and environmental factors.
Gašper Tonin   +6 more
wiley   +1 more source

Pain Phenotype in Knee Osteoarthritis: Implications for Mechanism‐Based Therapy

open access: yesOrthopaedic Surgery, EarlyView.
The paper reported on the precise and individual treatment of knee osteoarthritis (KOA) pain based on its new classification, including Nociceptive Pain, Neuropathic Pain, and Nociplastic Pain. Tailored treatment recommendations for different types of pain through exploring potential mechanisms of pain in KOA are provided to achieve better clinical ...
Chenchang He   +5 more
wiley   +1 more source

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