Results 121 to 130 of about 47,538 (286)

False nonresponders to anti‐calcitonin gene‐related peptide monoclonal antibodies: A real‐world analysis beyond migraine frequency reduction

open access: yesHeadache: The Journal of Head and Face Pain, EarlyView.
Abstract Objectives/Background Reimbursement criteria for anti‐calcitonin gene‐related peptide (CGRP) monoclonal antibodies (MAbs) typically rely on predefined reductions in monthly migraine days (MMD). However, this approach may fail to capture the full spectrum of treatment benefits, potentially leading to premature discontinuation in patients ...
Albert Muñoz‐Vendrell   +7 more
wiley   +1 more source

Simple, Rapid and Sensitive UV-Visible Spectrophotometric Method for Determination of Antidepressant Amitriptyline in Pharmaceutical Dosage Forms

open access: yesJournal of Spectroscopy, 2013
The paper describes a new and simple approach for spectrophotometric determination of tricyclic antidepressant drug amitriptyline. Enhancement of the colour intensity of the Fe(III)-SCN− complex on addition of the drug amitriptyline forms the basis of ...
Pankaj Soni, Deepak Sinha, Rajmani Patel
doaj   +1 more source

A retrospective audit of the real‐world safety and effectiveness profile of eptinezumab for treatment‐resistant chronic migraine in Australia

open access: yesHeadache: The Journal of Head and Face Pain, EarlyView.
Abstract Objective To describe the real‐world safety, tolerability, and effectiveness of eptinezumab for chronic migraine prevention in Australia. Background Eptinezumab is a relatively new medication for treatment‐resistant chronic migraine prevention.
Lakshini Gunasekera   +7 more
wiley   +1 more source

Use of Drugs With Actionable Pharmacogenetic Biomarkers and Possible Prescribing Changes Among Older People

open access: yesJournal of the American Geriatrics Society, EarlyView.
This graphical abstract illustrates the annual prevalence of exposure to CPIC Level A drugs among older adults, categorized by type of pharmacogenetic recommendation. Data are presented per 1000 older individuals (A) and per 1000 prescriptions (B).
Zinan Zhao   +11 more
wiley   +1 more source

Cryoglobulinemia: An update on classification, pathophysiology, clinical presentation, and management

open access: yesJournal of Internal Medicine, EarlyView.
Abstract Cryoglobulinemia (CG) is defined by the presence of serum immunoglobulins that precipitate below 37°C and redissolve upon rewarming. It is classified into three types based on immunoglobulin composition. Type I, a rare form, involves monoclonal IgM or IgG and is linked to lymphoproliferative disorders.
Anna Linda Zignego   +7 more
wiley   +1 more source

Parasomnias and sleep‐related movement disorders induced by drugs in the adult population: a review about iatrogenic medication effects

open access: yesJournal of Sleep Research, Volume 34, Issue 2, April 2025.
Summary Parasomnias and sleep‐related movement disorders (SRMD) are major causes of sleep disorders and may be drug induced. The objective of this study was to conduct a systematic review of the literature to examine the association between drug use and the occurrence of parasomnias and SRMD.
Sylvain Dumont   +5 more
wiley   +1 more source

Deconstructing lipid emulsion binding of amitriptyline: potential significance for phospholipid emulsifier

open access: yesToxicology Communications
Background Lipid emulsion (LE) consists of soybean or other oil emulsified with phospholipid. We explored relative binding effects of LE, phospholipid liposomes (PLL), and soy oil (Soy).Methods We added 4 micrograms of amitriptyline to seven different 10 
Grant Cave   +4 more
doaj   +1 more source

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