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The Effectiveness of Amitriptyline and Gabapentin in Treating Pomeranians with Chiari-like Malformation and/or Syringomyelia

Animals
Background: Chiari-like malformation (CM) and syringomyelia (SM) are commonly observed disorders in the Pomeranians. Both disorders can lead to pain and diminish quality of life to varying extents.
Ramona ter Maat +4 more
doaj +1 more source

Patient‐reported outcomes, postoperative pain and pain relief after day‐case surgery (POPPY): short‐term peri‐operative analgesic use

Anaesthesia, Volume 81, Issue 8, Page 1057-1067, August 2026.
Summary Introduction An increasing proportion of complex surgical procedures are being performed in the UK as day‐cases, with variable and limited follow up. Discharge prescriptions must provide adequate analgesia, while considering the safety of the patient and public, following best practice guidance and good opioid stewardship.
Anna Ratcliffe +2083 more
wiley +1 more source

Endothelium‐ and epithelium‐derived novel endogenous catecholamines as modulators of the autonomic nervous system

British Journal of Pharmacology, Volume 183, Issue 15, Page 4091-4110, August 2026.
Abstract Catecholamines are classically viewed as neuronal transmitters and adrenal hormones; however, accumulating evidence demonstrates that sources other than nerve fibres and adrenal medulla play a fundamental role in local organ regulation. Physiological paradoxes, such as preserved organ function after denervation or transplantation, challenge a ...
Mariana G. de Oliveira +3 more
wiley +1 more source

Effectiveness and Tolerability of Topical Amitriptyline 10% Plus Lidocaine 2% Gel in Adults With Post‐Traumatic Trigeminal Neuropathic Pain: A Real‐World Evidence Study

Journal of Oral Rehabilitation, Volume 53, Issue 8, Page 1550-1561, August 2026.
A compounded amitriptyline 10% plus lidocaine 2% mucoadhesive gel was associated with substantial pain improvement and favourable tolerability in adults with post‐traumatic trigeminal neuropathic pain (PTNP). These findings support targeted mucosal delivery as a promising practical local option and a potential medication‐sparing strategy, particularly ...
Ashley Lebel, Imen Stambouli, Yves Boucher +2 more
wiley +1 more source

Neuro‐Behçet's Disease and Psychiatric Disorders: From a Case Report to a Systematic Review

Brain and Behavior, Volume 16, Issue 7, July 2026.
ABSTRACT Background Behçet's disease is a chronic, relapsing systemic vasculitis that can affect multiple organ systems. Neurological involvement, known as neuro‐Behçet's disease, occurs in a subset of patients, while psychiatric manifestations—termed neuro‐psycho Behçet's disease—remain poorly characterized.
Jorge Renau +5 more
wiley +1 more source

A Probable Culture‐Specific Disorder of Pathological Weight Gain: Psychocultural Inversion of Anorexia Nervosa in Southern Morocco, Mauritania, and the Sahel

Psychiatric Research and Clinical Practice, EarlyView.
Mounir Jaafari +4 more
wiley +1 more source

Brachial Plexus Wrapping by Free Perforator Fat Flap for Treatment of Recurrent Neurogenic Thoracic Outlet Syndrome: A Case Report

Clinical Case Reports, Volume 14, Issue 7, July 2026.
ABSTRACT A 35‐year‐old woman with recurrent neurogenic thoracic outlet syndrome underwent supraclavicular neurolysis and brachial plexus wrapping using a free DIEP flap. At 2‐year follow‐up, pain and functional scores (VAS, DASH, SF‐36) significantly improved. Free fat flaps offer a low morbidity option for reducing perineural fibrosis in RNTOS.
F. Thuau +4 more
wiley +1 more source

Locally Aggressive Desmoid Tumor With L4–L5 Vertebral Invasion and Progressive Neurological Deficit: A Case Report

Clinical Case Reports, Volume 14, Issue 7, July 2026.
ABSTRACT Desmoid‐type fibromatosis is a rare, non‐metastatic fibroblastic neoplasm that may cause major morbidity through locally infiltrative growth. Spinal involvement with vertebral destruction and neurological deficit is particularly uncommon and may mimic malignant spindle‐cell or primary osseous tumors.
Ghada A. AlAnsari +4 more
wiley +1 more source

Postherpetic Neuralgia: Mechanisms, Risk Factors, and Stratified Management—A Narrative Review

CNS Neuroscience &Therapeutics, Volume 32, Issue 7, July 2026.
The incidence of PHN is increasing, posing a substantial public health burden. Its pathogenesis involves VZV reactivation, peripheral and central sensitization, and genetic susceptibility, with key risk factors including older age, severe acute pain, extensive rash, immunocompromise, comorbidities, and delayed treatment.
Fei Tang, Fukun Zhao
wiley +1 more source

Drug Critical Limits for Urgent Physician Notification

Clinical Pharmacology &Therapeutics, Volume 120, Issue 1, Page 178-192, July 2026.
Critical limits represent quantitative decision thresholds for drugs that require immediate clinician notification and potential life‐saving intervention. United States hospitals lack a national standard for drug critical limits. We collected critical limits from 417 US hospitals across all 50 states and Washington, D.C.; of these, 411 maintained drug ...
Elina Kuang +3 more
wiley +1 more source

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