Results 151 to 160 of about 29,828 (259)

Neuropathic Pain: From Mechanisms to Therapeutic Interventions

MedComm, Volume 7, Issue 10, October 2026.
Neuropathic pain arises from peripheral nerve injury, central sensitization, neurotransmitter imbalance, neuroimmune activation, and maladaptive circuit remodeling. Clinical phenotyping and multimodal imaging can identify dominant peripheral and central mechanisms.
Yaling Dai, Mengquan Tan, Man Yuan, Huixian Zhou, Qin Xie, Jiling Zeng, Yixin Yang, Xinran He, Siyuan Song   +8 more
wiley   +1 more source

Effects of Inhaled Amitriptyline on Airway Function and Immune Responses in Experimental Asthma. [PDF]

Adv Respir Med
Michely A, Böll S, Yao L, Ben Hamza R, Rachimow I, Tenbrock K, Martin C, Verjans E.   +7 more
europepmc   +1 more source

Prevention of amitriptyline-induced avoidance impairment by tacrine in mice.

, 1997
The effects of two cognition enhancers on avoidance impairment induced by the tricyclic antidepressant amitriptyline were assessed during shuttle-box avoidance acquisition and in previously trained mice of the DBA/2 strain. The nootropic agent piracetam (
Pavone F, Battaglia M, Sansone M
core  

High Prevalence and Clinical Impact of Fibromyalgia in Functional Motor Disorder

Movement Disorders Clinical Practice, Volume 13, Issue 10, Page 2564-2569, October 2026.
Abstract Background Fibromyalgia is characterized by widespread pain, fatigue, sleep and cognitive symptoms. It overlaps clinically with functional motor disorder (FMD), yet its prevalence and impact in FMD remain uncertain. Objective To determine the prevalence of fibromyalgia in FMD using the current criteria and evaluate its effects on motor ...
Tereza Serranová, Lucia Nováková, Martin Jirásek, Barbora Křupková, Evžen Růžička, Michele Tinazzi, Tomáš Sieger   +6 more
wiley   +1 more source

Amitriptyline versus the rest: still the leading antidepressant after 40 years of randomised controlled trials

, 2001
Background Tricyclic antidepressants have similar efficacy and slightly lower tolerability than selective serotonin reuptake inhibitors (SSRls). However, there are no systematic reviews assessing amitriptyline, the reference tricyclic drug, v.
Barbui, C, Hotopf, M, HOTOPF M., BARBUI, Corrado   +3 more
core  

Mechanism‐Informed Pharmacotherapy Optimization and Deprescribing: A Redox–Mitochondrial Framework

Pharmacology Research &Perspectives, Volume 14, Issue 5, October 2026.
From cumulative drug burden to mitochondrial stress and functional decline. The graphical abstract summarizes the central concept of the review, illustrating how cumulative pharmacotherapy exposure may contribute to redox–mitochondrial stress and thereby reduce biological and functional resilience.
Boštjan Martinc
wiley   +1 more source

Comparative Effectiveness of Pregabalin With Duloxetine Versus Pregabalin With Amitriptyline in Chronic Low Back Pain With Radiculopathy: A Prospective Comparative Study. [PDF]

Health Sci Rep
Khanam SM, Sarker SK, Mullick AR, Anwar SNMR.   +3 more
europepmc   +1 more source

Recent progress on the development of hydrogel‐based microneedles for transdermal drug delivery

VIEW, Volume 7, Issue 5, October 2026.
This study provides a comprehensive and up‐to‐date analysis of recent progress in HMN technology, covering fundamental transdermal delivery mechanisms and design principles, biomaterials used in HMN fabrication, drug loading and release strategies, and emerging therapeutic applications.
Mohammad Muhtasim Ittisaf, Salman Farsi Taharat, Md. Sadek Miah, Hasan Tasnim Salehin, M. Azam Ali, Shoeb Ahmed   +5 more
wiley   +1 more source

Inhibition of sodium-calcium exchanger by tricyclic antidepressants. [PDF]

Front Pharmacol
Boikov SI, Karelina TV, Nikolaev MV, Sibarov DA.   +3 more
europepmc   +1 more source

Clinical research updates

Child and Adolescent Mental Health, Volume 31, Issue 4, Page 368-370, November 2026.
Marinos Kyriakopoulos, Fotios Cheimaras, Asimina Palaiologou, Vasiliki Kyriakopoulou   +3 more
wiley   +1 more source