Results 161 to 170 of about 29,828 (259)

Tricyclic Antidepressant Poisoning: A 6-year Retrospective Observational Cross-sectional Analysis of Emergency Department Presentation, Clinical Severity, and Hospital Outcomes in a Tertiary Academic Center. [PDF]

Indian J Crit Care Med
Sahayaraj RG, Hazra D, Chandy GM, Thangaraju L.   +3 more
europepmc   +1 more source

From Real World Data to Real Impact: A Co‐Medication Framework for Lung Cancer to Advance DDI Assessment and Patient‐Centric Drug Development

Clinical and Translational Science, Volume 19, Issue 10, October 2026.
ABSTRACT Lung cancer predominantly affects older adults who already experience comorbidities and are at increased risk of drug–drug interactions (DDIs) due to polypharmacy. Traditional DDI assessments often do not fully capture complex co‐medication patterns observed in real‐world practice due to the risk of introducing confounding factors.
Mareena Biju, HeeJae Choi, Shilpa Madari, Annie Carlisle, Ashish Sharma, Christina Kunz, Fenglei Huang   +6 more
wiley   +1 more source

Migraine in Older Adults: Age‐Related Clinical Features From the Italian RICe Registry

European Journal of Neurology, Volume 33, Issue 10, October 2026.
This multicentre study of 3477 patients from 30 Italian headache centres identified distinct age‐related patterns in migraine. Older adults more frequently presented with chronic migraine, higher monthly migraine frequency, lower pain intensity, and medication‐overuse headache, as well as distinct trigger and preventive treatment patterns.
Giulia Paparella, Luigi Francesco Iannone, Giulia Paparella, Grazia Sances, Roberto De Icco, Gloria Vaghi, Cristina Tassorelli, Andrea Burgalassi, Francesco De Cesaris, Alberto Chiarugi, Francesca Gabriele, Raffaele Ornello, Simona Sacco, Maria Pia Prudenzano, Martino Gentile, Damiano Paolicelli, Giorgia Dalla Volta, Marco Bolchini, Innocenzo Rainero, Elisa Rubino, Maria Albanese, Fabrizio Vernieri, Gianluca Coppola, Gianluca Avino, Edoardo Mampreso, Delfina Ferrandi, Marta Altieri, Stefania Battistini, Antonio Granato, Simona Guerzoni, Antonio Russo, Marina de Tommaso, the RICe Study Group, Paola Merlo, Alessandro Viganò, Massimo Alessandri, Lucia Princiotta Cariddi, Milena Taglioli, Mariarosaria Valente, Rosaria Rapisarda, Alessandro Tiezzi, Giovanna Ballerini, Giovanna Viticchi, Catello Vollono, Luisa Fofi, Antonio Montisano, Licia Grazzi, Eugenia Rota   +47 more
wiley   +1 more source

Prolonged Tricyclic Antidepressant Toxicity in a Pediatric Patient: The Importance of Understanding the Multifactorial Nature of Amitriptyline Metabolism. [PDF]

Cureus
Navarro AW, Sahhar H.
europepmc   +1 more source

Framework for headache management in pediatric patients with stroke and cerebrovascular lesions: A narrative review

Headache: The Journal of Head and Face Pain, Volume 66, Issue 9, Page 2138-2155, October 2026.
Abstract Objective To present a practical, evidence‐based framework for the management of headache disorders in pediatric patients with prior stroke or underlying cerebral vascular lesions, with particular attention to safety and efficacy of pharmacologic and non‐pharmacologic therapies.
Allison C. Hyland, Samuel J. Belfer, Christine K. Fox, Samantha L. Irwin, Rachel Vassar, Ann Oh, Sruthi Ilangovan, Amy A. Gelfand   +7 more
wiley   +1 more source

The real-world safety profile of amitriptyline: A comprehensive pharmacovigilance analysis based on the large-scale FDA adverse event reporting system database. [PDF]

Neurotherapeutics
Yang Y, Xie Y, Hou L, Liu X.
europepmc   +1 more source

A novel redox signalling axis mediates nicotine-induced podocyte injury. [PDF]

Front Pharmacol
Rahman MA, Yellu R, Pavirala V, Datta S, Koka S, Boini KM.   +5 more
europepmc   +1 more source

Comparison of pharmacogenomic guidance in Australian prescribing resources and international pharmacogenomic guidelines

Internal Medicine Journal, Volume 56, Issue 10, Page 1765-1774, October 2026.
Abstract Background Pharmacogenomic‐guided medication management optimises drug therapy to enhance patient outcomes. Despite clinical utility, implementation in Australia remains limited, partly due to the lack of clear and consistent guidance. Aim This study evaluated the presence and consistency of pharmacogenomic testing indication categories and ...
Ruby Soueid, Jackson L. A. Thomas, Luke B. Hesson, Stephen Hughes, Sophie L. Stocker   +4 more
wiley   +1 more source

Efficacy of Antidepressants in Treating Functional Abdominal Pain Disorders in Children: A Meta-Analysis of Randomized Controlled Trials. [PDF]

Pediatr Gastroenterol Hepatol Nutr
Kim YJ, Kim NW, Park SH, Jung HY.
europepmc   +1 more source

Bridging gaps in diabetic neuropathy care: A Delphi‐based regional consensus from the Gulf Cooperation Council

Journal of Diabetes Investigation, Volume 17, Issue 10, Page 1643-1657, October 2026.
A three‐round Delphi consensus developed GCC‐specific, evidence‐based recommendations for diabetic peripheral neuropathy (DPN) and painful diabetic neuropathy (PND). The consensus emphasizes proactive screening, early multimodal management, and addressing regional barriers to improve early detection, optimize management, and enhance quality of life ...
Abdulrahman Alshaikh, Abdulnabi T Alattar, Ahmed Abdul Karim Hassoun, Afaf Alshammary, Hussein Elbadawi, Khaled Aldossari, Noor Al Busaidi, Saud Alsifri, Talal Muzaffar, Wiam I. Hussein, Christine Talaat, Abanoub Effat, Marwa Elsaghier, Rayaz A Malik   +13 more
wiley   +1 more source