Results 131 to 140 of about 36,705 (184)
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Chronopharmacology of amitriptyline

Clinical Pharmacology and Therapeutics, 1983
Side effects of decreased salivation and sedation were more marked when a single dose of amitriptyline was taken orally in the morning than in the evening. These dynamic differences were due to alteration in kinetics. Absorption of the drug was more rapid in the morning, although other kinetic parameters, especially total bioavailability, were ...
Shigeyuki Nakano   +3 more
openaire   +4 more sources

Fullerene (C20) as a potential sensor for thermal and electrochemical detection of amitriptyline: A DFT study

, 2020
In this research, amitriptyline adsorption on the surface of fullerene C20 was studied by density functional theory computations. The calculated adsorption energies showed amitriptyline interaction with C20 is experimentally possible. The negative values
Mohammad Reza Jalali Sarvestani   +1 more
semanticscholar   +1 more source

Abuse of Amitriptyline

JAMA: The Journal of the American Medical Association, 1978
Amitriptyline hydrocholride (Elavil) is frequently used in treating mild to moderate depressive states. A survey of 346 persons enrolled in a methadone maintenance program showed that 86 (25%) had admitted taking amitriptyline with the purpose of achieving euphoria. Thin-layer chromatography of random urine specimens over five months showed that 34% of
Raymond Hanbury   +2 more
openaire   +3 more sources

Amitriptyline and Amitriptyline-with-Perphenazine in Depression—A Retrospective Study

British Journal of Psychiatry, 1967
The object of this paper is to assess, in retrospect, the relative effectiveness of amitriptyline (‘Triptizol’) and amitriptyline with perphenazine (‘Triptafen’) in the treatment of depressed patients.
C. Chacón, E. T. Downham
openaire   +3 more sources

A comparison of amitriptyline, vasopressin and amitriptyline with vasopressin in nocturnal enuresis

Pediatric Nephrology, 1995
Forty-five children aged 6-14 years with primary nocturnal enuresis were randomised to determine whether desmopressin is more effective than amitriptyline and whether the combination of amitriptyline/desmopressin is more effective than amitriptyline or desmopressin alone.
John Burke   +3 more
openaire   +3 more sources

Amitriptyline in childhood enuresis

Clinical Pharmacology & Therapeutics, 1966
In a double‐blind, placebo‐controlled study with cross‐over, 50 outpatient enuretic children (aged 5 to 15) were treated for 8 weeks. It was found that amitriptyline in doses of 25 or 50 mg. (for children aged 12 and over) was superior clinically (P < 0.0005) to a placebo in decreasing the frequency of nights with enuresis.
Alvin F. Poussaint   +2 more
openaire   +3 more sources

Repeated Administration of Amitriptyline in Neuropathic Pain: Modulation of the Noradrenergic Descending Inhibitory System

Anesthesia and Analgesia, 2017
BACKGROUND The tricyclic antidepressant amitriptyline, the serotonin and noradrenaline reuptake inhibitor duloxetine, and gabapentinoids are first-line drugs for treatment of neuropathic pain.
Tadanao Hiroki   +3 more
semanticscholar   +2 more sources

Contribution to the Pharmacokinetics of Amitriptyline

The Journal of Clinical Pharmacology, 1978
The clinical pharmacokinetics of amitriptyline were studied in four volunteers after the oral administration of 75 mg. Peak amitriptyline plasma concentrations ranged from 10.8 to 43.7 ng/ml. The disappearance was biphasic and followed first-order kinetics. The mean elimination half-life was 36.1 hours.
Samuel H. Rosen   +3 more
openaire   +2 more sources

Photosensitized Degradation of Amitriptyline and Its Active Metabolite Nortriptyline in Aqueous Fulvic Acid Solution.

Journal of Environmental Quality, 2017
Amitriptyline is a frequently prescribed tricyclic antidepressant. Although amitriptyline and its active metabolite, nortriptyline, have been widely detected in natural waters, their environmental fate due to photodegradation is poorly understood.
Yong Chen   +6 more
semanticscholar   +1 more source

Amitriptyline‐induced ophthalmoplegia

Neurology, 1981
Total external ophthalmoplegia, unresponsive to caloric stimulation, was observed in a gravid woman who had ingested approximately 1.0 to 1.5 gm of amitriptyline. The intravenous administration of 4.0 mg physostigmine salicylate (PS) produced a revival of consciousness and reflex activity but had no appreciable effect on ocular motility.
Robert Schnapper, Robert H. Spector
openaire   +3 more sources

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