Results 141 to 150 of about 334,593 (294)

Pediatric AML

, 2022
Pediatric AML is a heterogeneous disease and in 30% of cases no apparent driving aberration can be detected. In this thesis, we have investigated novel driving aberrations in pediatric AML to improve risk group stratification and potentially identify novel targets for therapy to ultimately improve outcome.
openaire   +1 more source

Effect of Zinc Oxide Nanoparticles From Infant Formula Milk Powder on Colon Cells In Vitro

Journal of Applied Toxicology, EarlyView.
ABSTRACT Zinc is an essential trace element that participates in numerous metabolic processes; however, excessive exposure may interfere with the absorption of other metals, such as copper. In recent years, nanotechnology has experienced rapid growth, and zinc oxide nanoparticles (ZnO NPs) have garnered significant attention due to their versatile ...
Gloria Salinas‐Lucero, Karla Juarez‐Moreno, Rafael Vazquez‐Duhalt   +2 more
wiley   +1 more source

Surface CD81 supports leukemia stem cell function and reveals a therapeutic vulnerability in acute myeloid leukemia. [PDF]

Signal Transduct Target Ther
Gonzales F, Peyrouze P, Laurent D, Boyer T, Boukrout N, Couturier C, Houdiard S, Lisi V, Barthélémy A, Sevrin F, Plesa A, Bongiovanni A, Pottier N, Preudhomme C, Lavallée VP, Geles K, Duployez N, Berthon C, Roumier C, Cheok M.   +19 more
europepmc   +1 more source

The Application Value of Flow Cytometry‐Based Peripheral Blood Leukocyte Classification in Screening for Acute Leukemia and Posttreatment Monitoring

Journal of Clinical Laboratory Analysis, EarlyView.
Example of leukocyte classification results by FCM. The 16 cell populations are displayed in different colors according to the set gate logic. ABSTRACT Objective Assess the application value of flow cytometry (FCM) for peripheral blood leukocyte (PBL) classification in acute leukemia (AL) screening and monitoring.
Penghua Yan, Lianfeng Wu, Xiangyang Lin, Hong Lu, Jingjing Qian   +4 more
wiley   +1 more source

Distinct immunophenotypic and clinical features of TP53-mutated acute myeloid leukemia: high CD34/CD41 expression and lower leukocyte counts. [PDF]

Ann Hematol
Park S, Kim SA, Kim S, Kim SY, Lee JY, Byun JM, Hwang SM, Lee JO, Koh Y, Hong J, Chang YH, Kim HK, Bang SM, Kim I, Yoon SS, Shin DY.   +15 more
europepmc   +1 more source

Exportin 1 Inhibitor Combined With Venetoclax Induces Apoptosis in Myelodysplastic Syndrome by Mitochondria‐Induced Apoptosis Pathway

Journal of Clinical Laboratory Analysis, EarlyView.
Inhibition of XPO1 is a promising modality in the treatment of MDS, especially when combined with Venetoclax, which activates mitochondria‐mediated apoptosis and could be a potential target for MDS therapy. ABSTRACT Background Myelodysplastic syndromes (MDS) are clonal hematopoietic malignancies that pose a serious health threat.
Xiaohan Liu, Lei Huang, Junzhu Wang, Yixuan Guo, Hongli Shen, Xianghong Zhao, Lanzhu Yue, Zhaoyun Liu, Rong Fu   +8 more
wiley   +1 more source

Exploring the prognostic impact and biological functions of mutant-like TP53-related genes in acute myeloid leukemia. [PDF]

Hematol Transfus Cell Ther
Bertoline LMF, Coelho-Silva JL, Lima K, Rego EM, Machado-Neto JA.   +4 more
europepmc   +1 more source

Myeloid sarcoma presenting as an isolated pancreatic mass in a 3‐year‐old child

JPGN Reports, EarlyView.
Abstract Myeloid sarcoma (MS) is an extramedullary tumor of myeloid precursor cells, frequently associated with acute myeloid leukemia (AML), and rarely occurring in isolation. We present a child with obstructive jaundice secondary to a pancreatic head mass.
Jappmann Kaur Monga, Cara L. Mack, Michelle Saad, Dylan Applin, Maisam Abu‐El‐Haija, David Vitale, Zachary Graff, Gila Ginzburg   +7 more
wiley   +1 more source

m6A Modification of ATOX1 Inhibits Acute Myeloid Leukemia Progression by Promoting Cuproptosis. [PDF]

Cancer Res Commun
Peng J, Fu X, Li S, Hu C, Zhao X, Peng J.   +5 more
europepmc   +1 more source

Abnormal Eosinophils With Large, Distinctly Basophilic Granules (Harlequin Cells) on Peripheral Blood Smear: A Clue for Diagnosing Chronic Myeloid Leukemia. [PDF]

J Hematol
Cai J, Yue C, Tomassetti S.
europepmc   +1 more source