Results 121 to 130 of about 334,593 (294)
Objective To identify autoantibodies in presymptomatic individuals that associate with the onset of rheumatoid arthritis (RA), and to distinguish early RA from osteoarthritis (OA), particularly in individuals lacking classic RA serological markers. Methods We analyzed serum and plasma from three cohorts: pre‐symptomatic individuals who later developed ...
Outi Sareila +12 more
wiley +1 more source
Integrated stratigraphy of the Upper Hauterivian to Lower Barremian Agua de la Mula Member of the Agrio Formation, Neuquén Basin, Argentina [PDF]
The Upper Hauterivian to Lower Barremian Agua de la Mula Member of the Agrio Formation (Neuquén Basin, Argentina) was studied applying an integrated stratigraphic approach and facies analysis.
Archuby, Fernando +2 more
core
Objective We aimed to characterize CD4+ T cell plasticity in human SLE by leveraging TCR repertoire features as markers of prior lineage states, integrating TCR and transcriptomic profiling to delineate plasticity patterns and evaluate their association with clinical disease activity.
Yasuo Nagafuchi +11 more
wiley +1 more source
Background Information on mitoxantrone pharmacokinetics in children is lacking and reduced dosing regimens applied to infants are supported by limited scientific rationale. The current study characterized mitoxantrone pharmacokinetics in a childhood acute myeloid leukaemia patient population and provides a data‐informed assessment of dosing.
Andrew M. Brandon +13 more
wiley +1 more source
Aims Paediatric pharmacokinetics differ significantly from adults due to age‐related physiological changes, necessitating precise dose adjustments. However, data on therapeutic drug monitoring (TDM) implementation in paediatric setting remain limited.
Gianluca Gazzaniga +20 more
wiley +1 more source
Rule-based air combat simulation [PDF]
An improved version of the Adaptive Maneuvering Logic (AML) program for air-combat maneuvering is discussed.
Burgin, G. H., Sidor, L. B.
core +1 more source
Carrier‐free self‐assembled nanomedicine for combination‐therapy of acute myeloid leukemia
CPDS combines drugs with three different mechanisms of action to achieve a multi‐mechanism combination therapy for AML by directly killing tumor cells and activating anti‐tumor immunity. Abstract As the main acute myeloid leukemia (AML) clinical treatment, the chemotherapy alone cannot meet the clinical therapeutic needs due to the high heterogeneity ...
Meihong Chai +14 more
wiley +1 more source
Delocalization and higher-order topology in a nonlinear elastic lattice
Topological elastic waves provide novel and robust ways for manipulating mechanical energy transfer and information transmission, with potential applications in vibration control, analog computation, and more. Recently discovered higher-order topological
Jianlin Yi, Chang Qing Chen
doaj +1 more source
The evidence base for ranger patrol effectiveness in conservation and how to improve it
ABSTRACT Ranger patrols are a cornerstone of wildlife protection efforts around the world and occur across all ecological governance systems. Evidence that patrols reduce threats to wildlife and enable their recovery has not been systematically examined previously.
Trina Rytwinski +19 more
wiley +1 more source
The inverted F‐type ZnWO4/In2S3 heterojunction enables efficient charge separation and retention of strong oxidative capability through interfacial electric field regulation, leading to non‐toxic degradation of contaminants for sustainable water treatment.
Yanxian Jin +9 more
wiley +1 more source

