Results 111 to 120 of about 334,593 (294)

Particular object retrieval with integral max-pooling of CNN activations [PDF]

open access: yes, 2016
Recently, image representation built upon Convolutional Neural Network (CNN) has been shown to provide effective descriptors for image search, outperforming pre-CNN features as short-vector representations.
Jégou, Hervé   +2 more
core   +1 more source

Transcriptomic validation of a 7,12 Dimethylbenz(a)anthracene (DMBA)‐induced leukemia rat model: Parallels with human leukemogenesis

open access: yesAnimal Models and Experimental Medicine, EarlyView.
7,12‐Dimethylbenz[a]anthracene (DMBA) could induce leukemia and other types of cancers in rat models. Transcriptomics revealed gene expression profile that parallels with human leukemia. DMBA‐induced differential gene expression could validate the developed rat model.
Khaldoon Alsamman, Omar S. El‐Masry
wiley   +1 more source

SETD2 in MLL-rearranged leukemia – a complex case

open access: yesMolecular & Cellular Oncology, 2018
Oncogenic MLL-fusion proteins often hijack essential molecular mechanisms during leukemogenesis. The histone methyltransferase SETD2 was implicated in the regulation of transcription, DNA damage and other cellular processes.
Anna Skucha   +2 more
doaj   +1 more source

Epitheloid Variant of Angiomyolipoma in a Patient with Tuberous Sclerosis. [PDF]

open access: yes, 2013
Epitheloid angiomyolipoma of kidney is a type of Perivascular endothelial cell derived tumor with an aggressive behaviour with specific pathological, immunohistochemistrical and genetic characteristics.
Amirtham, U   +4 more
core   +1 more source

USB1 deficiency disrupts neutrophil maturation via RNA dysregulation independent of global pre‐mRNA splicing

open access: yesAnimal Models and Experimental Medicine, EarlyView.
This graphical abstract illustrates the essential role of USB1 in neutrophil maturation. In normal myeloid cells, USB1 acts as an RNA exonuclease, trimming RNA tails to maintain proper RNA network function, which supports the differentiation of myeloid progenitor cells into mature neutrophils.
Hang Li   +6 more
wiley   +1 more source

Targeting pseudokinase TRIB3 brings about a new therapeutic option for acute promyelocytic leukemia

open access: yesMolecular & Cellular Oncology, 2017
Pseudokinase tribbles (Trib) family, Trib1 and Trib2, but not Trib3, act as oncogene to drive acute leukemia by destabilizing the myeloid transcription factor CCAAT/enhancer-binding protein α (C/EBPα) and inhibiting myeloid differentiation.
Ke Li, Feng Wang, Zhuo-Wei Hu
doaj   +1 more source

On the Effect of Magnetic Spots on Stellar Winds and Angular Momentum Loss

open access: yes, 2009
We simulate the effect of latitudinal variations in the location of star spots, as well as their magnetic field strength, on stellar angular momentum loss to the stellar wind.
Antia   +32 more
core   +1 more source

Novel Monoclonal Antibody Detects Small Aβ Oligomers More Sensitively Than Lecanemab in Alzheimer's Disease CSF, Serum and Culture Media

open access: yesAnnals of Neurology, EarlyView.
Objective Aqueously diffusible oligomers of the amyloid β‐protein (oAβ) are neurotoxic and play a role in neuronal dysfunction in Alzheimer's disease (AD). Accurate quantification of oAβ in brains and biofluids could be valuable for understanding and monitoring AD.
Yi Ran Xu   +11 more
wiley   +1 more source

The petrotympanic canal (Huguier canal): Evolutionary, anatomical, and medical perspectives

open access: yesThe Anatomical Record, EarlyView.
Abstract The petrotympanic canal, traditionally referred to as Civinini's or Huguier's canal, represents an anatomical passage connecting the middle ear and temporomandibular joint (TMJ). Despite its early description, its structural complexity and functional significance have often been underestimated. In this study, we combined historical, anatomical,
Andrea Papini   +8 more
wiley   +1 more source

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