New anticancer therapies with potential cardiovascular side effects are continuously being introduced into clinical practice, with new and often unexpected toxicities becoming apparent only after clinical introduction. These unknown toxicities should be identified and understood beforehand to better prepare patients and physicians, enabling the ...
Alessandra Ghigo+22 more
wiley +1 more source
Delocalization and higher-order topology in a nonlinear elastic lattice
Topological elastic waves provide novel and robust ways for manipulating mechanical energy transfer and information transmission, with potential applications in vibration control, analog computation, and more. Recently discovered higher-order topological
Jianlin Yi, Chang Qing Chen
doaj +1 more source
Effect of Diagnosis (Refractory Anemia With Excess Blasts, Refractory Anemia With Excess Blasts in Transformation, or Acute Myeloid Leukemia [AML]) on Outcome of AML-Type Chemotherapy [PDF]
Elihu H. Estey+5 more
openalex +1 more source
In the PRIME‐MR study, patients with higher N‐terminal pro‐B‐type natriuretic peptide (NT‐proBNP) tertiles more frequently reached death or heart failure hospitalization (HFH) within 3 years. Log‐transformed NT‐proBNP levels independently predicted the primary endpoint (adjusted hazard ratio 1.17, 95% confidence interval 1.07–1.28; p < 0.001).
Philipp von Stein+70 more
wiley +1 more source
Multiple Cbfa/AML Sites in the Rat Osteocalcin Promoter Are Required for Basal and Vitamin D-Responsive Transcription and Contribute to Chromatin Organization [PDF]
Amjad Javed+6 more
openalex +1 more source
Hierarchy in Gene Expression is Predictive for Adult Acute Myeloid Leukemia
Cancer progresses with a change in the structure of the gene network in normal cells. We define a measure of organizational hierarchy in gene networks of affected cells in adult acute myeloid leukemia (AML) patients.
Deem, Michael W., Tripathi, Shubham
core +1 more source
Aclacinomycin-A in the Induction Treatment of Childhood AML
F. M. Fink+5 more
openalex +1 more source
The influence of HLA‐matched sibling donor availability on treatment outcome for patients with AML: an analysis of the AML 8A study of the EORTC Leukaemia Cooperative Group and GIMEMA [PDF]
S. Keating+14 more
openalex +1 more source
Epigenomics‐guided precision oncology: Chromatin variants in prostate tumor evolution
Abstract Prostate cancer is a common malignancy that in 5%–30% leads to treatment‐resistant and highly aggressive disease. Metastasis‐potential and treatment‐resistance is thought to rely on increased plasticity of the cancer cells—a mechanism whereby cancer cells alter their identity to adapt to changing environments or therapeutic pressures to create
Kira Furlano+6 more
wiley +1 more source
The Impacts of the Chinese Anti-Monopoly Law on IP Commercialization in China & General Strategies for Technology-Driven Companies and Future Regulators [PDF]
After thirteen years of discussion and three revisions, China\u27s Anti-Monopoly Law (AML) was promulgated on August 30, 2007 and has come into effect on August 1, 2008.
Tian, Yijun
core +1 more source