Results 11 to 20 of about 334,593 (294)

Tunable seesaw-like 3D capacitive sensor for force and acceleration sensing

npj Flexible Electronics, 2021
To address the resource-competing issue between high sensitivity and wide working range for a stand-alone sensor, development of capacitive sensors with an adjustable gap between two electrodes has been of growing interest.
Jilong Ye, Fan Zhang, Zhangming Shen, Shunze Cao, Tianqi Jin, Xiaogang Guo, Zhihong Li, Li Lin, Yihui Zhang   +8 more
doaj   +1 more source

A Multifunctional Bioelectronic Device with Switchable Rigidity and Reconfigurable Shapes for Comprehensive Diagnosis

Advanced Electronic Materials, 2023
Soft bioelectronic devices have potential in medical applications, especially comprehensive diagnoses that rely on immovable equipment to acquire multiple physiological signals.
Yang Jiao, Yingchao Zhang, Haijun Feng, Haibo Li, Zhouheng Wang, Peng Wang, Yutong Wang, Ning Zheng, Tao Xie, Yinji Ma, Xue Feng   +10 more
doaj   +1 more source

Targeting BTK for the treatment of FLT3-ITD mutated acute myeloid leukemia [PDF]

, 2015
Approximately 20% of patients with acute myeloid leukaemia (AML) have a mutation in FMS-like-tyrosine-kinase-3 (FLT3). FLT3 is a trans-membrane receptor with a tyrosine kinase domain which, when activated, initiates a cascade of phosphorylated proteins ...
A Puissant, AJ Mohamed, BD Smith, BJ Druker, C Chung, C Dos Santos, C Thiede, C Venkataraman, CC Smith, CK Hahn, F Heidel, F Honda, G Juliusson, H Kiyoi, HS Ma, J Adolfsson, JA Dubovsky, JA Dubovsky, JA Woyach, JA Woyach, JB Petro, K Fiedler, KU Birkenkamp, L Zaitseva, M Levis, M Nakao, ML Wang, N Feldhahn, NJ Horwood, PP Zarrinkar, Q Xu, RF Schlenk, RM Stone, S Knapper, S Meshinchi, SA Ezell, SA Rushworth, SA Rushworth, SA Rushworth, SA Rushworth, T Kindler, T Matsunaga, T Oellerich, T-l Gu, V Vijayan, W Gao, Y Alvarado, Y Baba, Y Yamamoto, Y-T Tai   +49 more
core   +2 more sources

Identification of Bruton's tyrosine kinase as a therapeutic target in acute myeloid leukemia [PDF]

, 2014
Bruton's tyrosine kinase (BTK) is a cytoplasmic protein found in all hematopoietic cell lineages except for T cells. BTK mediates signalling downstream of a number of receptors.
Advani, Alam, Ashino, Baba, Bendall, Billottet, Burger, Burger, Byrd, Chang, Cordle, Dasmahapatra, David J. MacEwan, de Weers, Dos Santos, Doyle, Fiedler, Gallay, Grandage, Gu, Guzman, Hahn, Herman, Herrmann, Honda, Honigberg, Horwood, Ishii, Juliusson, Kawakami, Kim, Kojima, Kristian M. Bowles, Kvinlaug, Lyubov Zaitseva, Megan Y. Murray, Min, Mohamed, Nanri, Park, Quek, Renneville, Rushworth, Rushworth, Rushworth, Shinners, Sivina, Spiekermann, Stuart A. Rushworth, Sujobert, Tai, Tamburini, Tomasson, Tsukada, Vellenga, Venkataraman, Vetrie, Welch, Westermann, Zaitseva   +59 more
core   +1 more source

In-memory mechanical computing

Nature Communications, 2023
Mechanical computing requires matter to adapt behavior according to retained knowledge, often through integrated sensing, actuation, and control of deformation.
Tie Mei, Chang Qing Chen
doaj   +1 more source

Polygonal non-wetting droplets on microtextured surfaces

Nature Communications, 2022
Exploring the interactions between liquids and solids is critical for improving control over fluidic systems. Here, authors develop an active way to tailor various polygonal shapes of non-wetting droplet on microtextured surfaces, resulting from the ...
Jing Lou, Songlin Shi, Chen Ma, Xiaohuan Zhou, Dong Huang, Quanshui Zheng, Cunjing Lv   +6 more
doaj   +1 more source

NRF2-driven miR-125B1 and miR-29B1 transcriptional regulation controls a novel anti-apoptotic miRNA regulatory network for AML survival [PDF]

, 2014
Transcription factor NRF2 is an important regulator of oxidative stress. It is involved in cancer progression, and has abnormal constitutive expression in acute myeloid leukaemia (AML).
A Ooi, AG Ooi, BN Chorley, BT Kvinlaug, C Luna, CR Zhao, D J MacEwan, E Estey, E Surdziel, F Kong, G Tan, GM DeNicola, H Wang, H Zhang, I Spinello, J Alam, J Gong, J Winter, JE Anderson, JJ Tsai, JJ Zhao, JN Gong, K M Bowles, K Okamoto, L Zaitseva, L Zaitseva, M Bousquet, M Bousquet, MB Sporn, MY Murray, N Hanada, N M Shah, P Moi, PA Konstantinopoulos, R Garzon, R Garzon, R Garzon, R Venugopal, S A Rushworth, S Liu, SA Rushworth, SA Rushworth, SA Rushworth, TWP Devling, W Blum, Y Wang, YR Kim   +46 more
core   +1 more source

Recent progress in three-dimensional flexible physical sensors

International Journal of Smart and Nano Materials, 2022
Three-dimensional (3D) functional systems are of rapidly growing interest over the past decade, from the perspective of both the fundamental and applied research.
Fan Zhang, Tianqi Jin, Zhaoguo Xue, Yihui Zhang   +3 more
doaj   +1 more source

Surface evolution and stability transition of silicon wafer subjected to nano-diamond grinding

AIP Advances, 2017
In order to obtain excellent physical properties and ultrathin devices, thinning technique plays an important role in semiconductor industry with the rapid development of wearable electronic devices.
Shisheng Cai, Changxing Zhang, Haicheng Li, Siyuan Lu, Yan Li, Keh-Chih Hwang, Xue Feng   +6 more
doaj   +1 more source

MUC1-C drives myeloid leukaemogenesis and resistance to treatment by a survivin-mediated mechanism [PDF]

, 2018
Acute myeloid leukaemia (AML) is an aggressive haematological malignancy with an unmet need for improved therapies. Responses to standard cytotoxic therapy in AML are often transient because of the emergence of chemotherapy-resistant disease.
Anastasiadou, Eleni, Avigan, David, Bar-Natan, Michal, Cole, Leandra, Coll, Maxwell D., Ephraim, Adam, Jain, Salvia, Kharbanda, Akriti, Kufe, Donald, Kufe, Turner, Leaf, Rebecca K., Nahas, Myrna, Orr, Shira, Palmer, Kristen, Pyzer, Athalia, Rahimian, Maryam, Rajabi, Hasan, Rosenblatt, Jacalyn, Stroopinsky, Dina, Tagde, Ashujit, Washington, Abigail   +20 more
core   +1 more source