Results 41 to 50 of about 219,440 (288)

FLT3 Length Mutations as Marker for Follow-Up Studies in Acute Myeloid Leukaemia [PDF]

open access: yes, 2004
Length mutations within the FLT3 gene (FLT3-LM) can be found in 23% of acute myeloid leukaemia (AML) and thus are the most frequent mutations in AML. FLT3-LM are highly correlated with AML with normal karyotype and other cytogenetic aberrations of the ...
Haferlach, Torsten   +4 more
core   +1 more source

On the origin of relapse in AML [PDF]

open access: yesScience Translational Medicine, 2017
Preexisting therapy-resistant leukemia stem cell populations underlie the cellular origin of relapse in acute myeloid leukemia.
openaire   +5 more sources

How to obtain a more accurate maximum energy release rate for mixed mode fracture

open access: yesForces in Mechanics, 2022
Energy release rate (ERR) is considered one of the most widely employed fracture criteria. However, for mixed mode fracture situations, the exact computation of ERR for an infinitesimal branch crack is challenging.
Huihan Chen   +3 more
doaj  

A Phase 1 study of intravenous infusions of tigecycline in patients with acute myeloid leukemia. [PDF]

open access: yes, 2016
Acute myeloid leukemia (AML) cells meet the higher energy, metabolic, and signaling demands of the cell by increasing mitochondrial biogenesis and mitochondrial protein translation.
Brandwein, Joseph   +14 more
core   +1 more source

Skin-integrated, biocompatible, and stretchable silicon microneedle electrode for long-term EMG monitoring in motion scenario

open access: yesnpj Flexible Electronics, 2023
Electromyography (EMG) signal is the electrical potential generated by contracting muscle cells. Long-term and accurate EMG monitoring is desirable for neuromuscular function assessment in clinical and the human–computer interfaces.
Huawei Ji   +10 more
doaj   +1 more source

Identification of pre-leukaemic haematopoietic stem cells in acute leukaemia. [PDF]

open access: yes, 2014
In acute myeloid leukaemia (AML), the cell of origin, nature and biological consequences of initiating lesions, and order of subsequent mutations remain poorly understood, as AML is typically diagnosed without observation of a pre-leukaemic phase.
Brandwein, Joseph M   +25 more
core   +2 more sources

Research on the Sensing Performance of the Tuning Fork-Probe as a Micro Interaction Sensor

open access: yesSensors, 2015
The shear force position system has been widely used in scanning near-field optical microscopy (SNOM) and recently extended into the force sensing area.
Fengli Gao, Xide Li
doaj   +1 more source

Animal crossing: New leaf and the diversity of horror in video games [PDF]

open access: yes, 2015
This paper explores the diverse ways horror can be conveyed in games by investigating how games that are not associated with the horror genre can produce unsettling or scary experiences.
Björn, M, Brown, AML
core  

B cell mechanobiology in health and disease: emerging techniques and insights into therapeutic responses

open access: yesFEBS Letters, EarlyView.
B cells sense external mechanical forces and convert them into biochemical signals through mechanotransduction. Understanding how malignant B cells respond to physical stimuli represents a groundbreaking area of research. This review examines the key mechano‐related molecules and pathways in B lymphocytes, highlights the most relevant techniques to ...
Marta Sampietro   +2 more
wiley   +1 more source

Heat Stress-Induced Multiple Multipolar Divisions of Human Cancer Cells

open access: yesCells, 2019
Multipolar divisions of heated cells has long been thought to stem from centrosome aberrations of cells directly caused by heat stress. In this paper, through long-term live-cell imaging, we provide direct cellular evidences to demonstrate that heat ...
Shaoyong Chen   +6 more
doaj   +1 more source

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