Machine Learning‐Based Prediction of Drug‐Induced QTc Changes in a Large Finnish Biobank Cohort
Clinical and Translational Science, Volume 19, Issue 5, May 2026.ABSTRACT Prolongation of the QT interval is a known precursor to serious arrhythmias and sudden cardiac death, often triggered by medication use. Current medication risk evaluation platforms rely on literature‐based synthesis and may lag behind real‐world developments.
Ville Langén +7 more
wiley +1 more source
Adherence with single-pill amlodipine/atorvastatin vs a two-pill regimen
Vascular Health and Risk Management, 2008 Bimal V Patel1, R Scott Leslie1, Patrick Thiebaud1, Michael B Nichol2, Simon SK Tang3, Henry Solomon3, Dennis Honda3, JoAnne M Foody41MedImpact Healthcare Systems, Inc., San Diego, CA, USA (Patrick Thiebaud was an employee of MedImpact Healthcare Systems,
Bimal V Patel +5 more
doaj
Current Issues in Pharmacy and Medical Sciences, 2014 Dissolution tests of amlodipine and perindopril from their fixed dose formulations were performed in 900 mL of phosphate buffer of pH 5.5 at 37°C using the paddle apparatus.
Maczka Paulina +3 more
doaj +1 more source
Non-equivalence of antibiotic generic drugs and risk for intensive care patients [PDF]
, 2013 Background: The underlying axiom in applying generic drugs is the equivalence of their active ingredient with the (usually more expensive) innovator product, an all-embracing statement with the insidious result that physicians assume that the generic ...
Barbeck, Mike +4 more
core
Pacing and Clinical Electrophysiology, Volume 49, Issue 5, Page 606-609, May 2026.ABSTRACT Background Permanent pacing in pediatric patients is complicated by small body size, vascular access limitations, and the need for durable long‐term management. Leadless pacemakers offer an emerging alternative that minimizes infection and lead‐related complications, yet vascular access remains a key challenge in young patients.
Marzia Giaccardi +4 more
wiley +1 more source
Profil Penggunaan Obat Pasien Hipertensi Esensial di Instalasi Rawat Jalan Rumah Sakit Umum Daerah I Lagaligo Kabupaten Luwu Timur Periode Januari-Desember Tahun 2014: Profile Of Drug Use In Patients With Essential Hypertension At Outpatient Installation General Hospital I Lagaligo Luwu Timur Regency Period Of January-December 2014 [PDF]
, 2017 This study aimed to determine the demographic and clinical characteristics and profile of drug use in patients with essential hypertension at outpatient installations I Lagaligo General Hospital East Luwu Regency period January-December 2014.
Faustine, I. (Ingrid) +2 more
core
ISFM Consensus Guidelines on the Diagnosis and Management of Feline Chronic Kidney Disease [PDF]
, 2016 Adams LG +19 more
core +1 more source
Use of Antihypertensive Agents and Association With Risk of Adverse Outcomes in Chronic Kidney Disease: Focus on Angiotensin-Converting Enzyme Inhibitors and Angiotensin Receptor Blockers. [PDF]
, 2018 Background Our objective was to determine patterns of antihypertensive agent use by stage of chronic kidney disease (CKD) and to evaluate the association between different classes of antihypertensive agents with nonrenal outcomes, especially in advanced ...
Johansen, Kirsten L +4 more
core
Clinical and Experimental HypertensionAmlodipine has been used as a front-line anti-hypertensive therapy for decades by virtue of blocking voltage-operated calcium channels with high affinity and specificity.
Gary S. Bird +6 more
doaj +1 more source