Results 21 to 30 of about 26,012 (179)

Bioequivalence study of fixed-dose combination Losartan + amlodipine + rosuvastatin Sanofi in comparison with coadministered fixed- dose combination Lozap® AM and monocomponent drug Crestor® in healthy subjects

Фармакокинетика и Фармакодинамика, 2022
Introduction. The advantages of fixed-dose combination losartan + amlodipine + rosuvastatin compared to mono-drugs and two-component combinations are to increase the therapeutic efficacy, to reduce the cost of the product and to make the drug easier to ...
A. L. Khokhlov, D. Yu. Grebenkin, E. K. Faeva, V. I. Kazey, A. A. Khokhlov, A. E. Miroshnikov, O. V. Lebedeva   +6 more
doaj   +1 more source

Association of Amlodipine with the Risk of In-Hospital Death in Patients with COVID-19 and Hypertension: A Reanalysis on 184 COVID-19 Patients with Hypertension

Pharmaceuticals, 2022
Association between calcium channel blockers (CCBs) or functional inhibitors of acid sphingomyelinase (FIASMAs) use and decreased mortality in people with COVID-19 has been reported in recent studies.
Gwenolé Loas, Philippe Van de Borne, Gil Darquennes, Pascal Le Corre   +3 more
doaj   +1 more source

Synergism of amlodipine and telmisartan or candesartan on blood pressure reduction by using SynergyFinder 3.0 and probability sum test in vivo

Pharmacology Research & Perspectives, 2023
This study was designed to evaluate the synergism of two couples of antihypertensive drugs (amlodipine + telmisartan and amlodipine + candesartan) on blood pressure reduction in vivo by both SynergyFinder 3.0 and probability sum test.
Tian Xia, Lu‐Lu Xu, Peng‐Yue Guo, Wan‐Ting Shi, Yan‐Qiong Cheng, Ai‐Jun Liu   +5 more
doaj   +1 more source

Amlodipine-induced gingival hyperplasia: A report of two cases

Journal of Clinical and Scientific Research, 2022
Drugs associated with gingival overgrowth fall into three broad categories – anticonvulsants, immune suppressants and calcium channel blockers. Amlodipine is a third-generation dihydropyridine. The prevalence of amlodipine-induced gingival hyperplasia is
G Sri Lakshmi, G Tejaswini, B Alekhya, Maria Bethasaida Manuel, R Ram, V Siva Kumar   +5 more
doaj   +1 more source

Severe ADEM‐Like Neuroinflammatory Disease and Cerebrovascular Fragility With Recurrent Pseudoaneurysms and Moyamoya in a Familial Germline CBL Mutation: Expanding the Clinical Phenotype

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Heterozygous germline variants in CBL disrupt its function as a negative regulator of the Ras/MAPK pathway, classically predisposing to Juvenile myelomonocytic leukemia (JMML) and moyamoya. We describe two affected siblings carrying a paternally inherited CBL variant (c.1210 T> C, p.
Michal Bar‐Hakim, Anat Abramovich, Sara Via‐Dorembus, Gali Heimer, Bruria Ben‐Zeev, Etai Adam, Assaf A. Barg, Jonathan Roth, Basheer Sheick‐Yousif, Rony Beeri Berkowiz, Michal Feldon, Haim Bassan, Moran Hausman‐Kedem   +12 more
wiley   +1 more source

Effects of curcumin on the pharmacokinetics of amlodipine in rats and its potential mechanism

Pharmaceutical Biology, 2020
Context Hyperlipidaemia and hypertension are often treated together with curcumin and amlodipine. It is necessary to investigate the drug-drug interaction between curcumin and amlodipine.
Na Jiang, Meicheng Zhang, Xiangzhi Meng, Bin Sun   +3 more
doaj   +1 more source

Amlodipine-induced gingival hyperplasia

National Journal of Physiology, Pharmacy and Pharmacology, 2021
Drug-induced gingival hyperplasia is the increased growth of gingival epithelium and submucosa which may cause bleeding and loss of teeth. Certain anticonvulsant, immunosuppressive, and antihypertensive drugs are the underlying cause in most cases. Among
Raghu N, Deepak P, Suresh R M, Manjula M J   +3 more
doaj   +1 more source

FORMULATION AND EVALUATION OF S-(-)-AMLODIPINE BESYLATE AND NEBIVOLOL HYDROCHLORIDE TABLETS [PDF]

Journal of Advanced Pharmaceutical Technology & Research, 2010
The objective of the present study was to develop a tablet formulation of S-(-)- amlodipine besylate chiral separation drug and nebivolol hydrochloride for better management of hypertension, while reducing or avoiding undesirable adverse effects, which ...
Shaikh S.A, Shaikh S.S, Shahi S.R., Shookur M.A., Reddy L.K, Padalkar A.N, Thube Mahesh   +6 more
doaj   +2 more sources

Trends in 25 years of antihypertensive agent utilization in Croatia – an alert for scientific community and healthcare providers

British Journal of Clinical Pharmacology, EarlyView.
Aims Hypertension is a leading modifiable risk factor for cardiovascular mortality worldwide. This study aimed to evaluate 25‐year trends in antihypertensive agent (AHA) utilization in Croatia between 2000 and 2024. Methods We conducted a national, population‐based analysis using IMS and IQVIA pharmaceutical databases.
Andrej Belančić, Marta Kučan Štiglić, Ana Jelaković, Bojan Jelaković, Dinko Vitezić   +4 more
wiley   +1 more source

Effects of triptolide on pharmacokinetics of amlodipine in rats by using LC–MS/MS

Pharmaceutical Biology, 2018
Context: Triptolide and amlodipine are often simultaneously used for reducing urine protein excretion after renal transplantation in China clinics. Objective: This study investigated the effects of triptolide on the pharmacokinetics of amlodipine in male
Chengyin Zhang, Zhiqiang Gao, Lijuan Niu, Xuexun Chen   +3 more
doaj   +1 more source