Results 31 to 40 of about 31,301 (226)

COMPARATIVE STUDY OF EFFICIENCY AND SAFETY OF THE NEW DRUG OF AMLODOPINE – S-AMLODOPINE IN PATIENTS WITH ARTERIAL HYPERTENSION OF I-II DEGREE

Рациональная фармакотерапия в кардиологии, 2016
Aim. To evaluate efficacy and safety of a new drug of amlodipine – S-amlodipine (Azomex, Emcur, India) compared to original drug of racemic amlodipine (Norvasc, Pfizer, USA) in patients with arterial hypertension (HT) of I-II grade.Material and methods ...
M. A. Maksimova, Y. V. Lukina, S. N. Tolpygina, E. V. Shilova, N. A. Dmitrieva, S. Y. Martsevich   +5 more
doaj   +1 more source

Impact of Cumin and Green Tea on Amlodipine Pharmacodynamics and Pharmacokinetics in Hypertensive Rats

Separations, 2023
The main purpose of the current research was to determine the impact of cumin and green tea on the pharmacodynamics and pharmacokinetics of amlodipine in hypertensive rats. Wistar rats were given 40 mg/kg of L-NAME orally every day for two weeks in order
Ibrahim Abdelsalam Abdelrahman, Abdul Ahad, Mohammad Raish, Yousef A. Bin Jardan, Mohd Aftab Alam, Fahad I. Al-Jenoobi   +5 more
doaj   +1 more source

Evaluating the Educational Value of Artificial Intelligence in Pharmacotherapy Education. [PDF]

Pharmacol Res Perspect
ABSTRACT Final‐year medical students frequently make prescribing errors, partly because they have had insufficient training in therapeutic reasoning. Students need to understand the underlying rationale behind a drug choice in order to subsequently apply that knowledge critically and independently.
Hartjes MG, Bakkum MJ, Richir MC, van Agtmael MA, Tichelaar J.   +4 more
europepmc   +2 more sources

Consequences of treatment by amlodipine and the association amlodipine-propranolol.

, 2022
The upper panel represents the survival curves on either active treatment or water. The lower panels represent SBP (lower bars: left scale) and HR (upper lines: right scale), measured between 8 and 24 weeks. Data are expressed as mean ±SEM.
Irmine Loisel-Ferreira (12197672), Julie Faugeroux (160678), Carole Beugnon (12197666), Salma Adham (11793374), Charline Guery (515320), Anne Legrand (11793380), Xavier Jeunemaitre (75863), Juliette Hadchouel (160693), Erika Fontaine (12197663), Amélie Gianfermi (12197669), Marie-Christine Verpont (8358036), Tristan Mirault (541128)   +11 more
core   +1 more source

Effects of curcumin on the pharmacokinetics of amlodipine in rats and its potential mechanism

Pharmaceutical Biology, 2020
Context Hyperlipidaemia and hypertension are often treated together with curcumin and amlodipine. It is necessary to investigate the drug-drug interaction between curcumin and amlodipine.
Na Jiang, Meicheng Zhang, Xiangzhi Meng, Bin Sun   +3 more
doaj   +1 more source

Bioequivalence study of fixed-dose combination Losartan + amlodipine + rosuvastatin Sanofi in comparison with coadministered fixed- dose combination Lozap® AM and monocomponent drug Crestor® in healthy subjects

Фармакокинетика и Фармакодинамика, 2022
Introduction. The advantages of fixed-dose combination losartan + amlodipine + rosuvastatin compared to mono-drugs and two-component combinations are to increase the therapeutic efficacy, to reduce the cost of the product and to make the drug easier to ...
A. L. Khokhlov, D. Yu. Grebenkin, E. K. Faeva, V. I. Kazey, A. A. Khokhlov, A. E. Miroshnikov, O. V. Lebedeva   +6 more
doaj   +1 more source

Association of Amlodipine with the Risk of In-Hospital Death in Patients with COVID-19 and Hypertension: A Reanalysis on 184 COVID-19 Patients with Hypertension

Pharmaceuticals, 2022
Association between calcium channel blockers (CCBs) or functional inhibitors of acid sphingomyelinase (FIASMAs) use and decreased mortality in people with COVID-19 has been reported in recent studies.
Gwenolé Loas, Philippe Van de Borne, Gil Darquennes, Pascal Le Corre   +3 more
doaj   +1 more source

Amlodipine-induced gingival hyperplasia: A report of two cases

Journal of Clinical and Scientific Research, 2022
Drugs associated with gingival overgrowth fall into three broad categories – anticonvulsants, immune suppressants and calcium channel blockers. Amlodipine is a third-generation dihydropyridine. The prevalence of amlodipine-induced gingival hyperplasia is
G Sri Lakshmi, G Tejaswini, B Alekhya, Maria Bethasaida Manuel, R Ram, V Siva Kumar   +5 more
doaj   +1 more source

Synergism of amlodipine and telmisartan or candesartan on blood pressure reduction by using SynergyFinder 3.0 and probability sum test in vivo

Pharmacology Research & Perspectives, 2023
This study was designed to evaluate the synergism of two couples of antihypertensive drugs (amlodipine + telmisartan and amlodipine + candesartan) on blood pressure reduction in vivo by both SynergyFinder 3.0 and probability sum test.
Tian Xia, Lu‐Lu Xu, Peng‐Yue Guo, Wan‐Ting Shi, Yan‐Qiong Cheng, Ai‐Jun Liu   +5 more
doaj   +1 more source

Severe ADEM‐Like Neuroinflammatory Disease and Cerebrovascular Fragility With Recurrent Pseudoaneurysms and Moyamoya in a Familial Germline CBL Mutation: Expanding the Clinical Phenotype

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Heterozygous germline variants in CBL disrupt its function as a negative regulator of the Ras/MAPK pathway, classically predisposing to Juvenile myelomonocytic leukemia (JMML) and moyamoya. We describe two affected siblings carrying a paternally inherited CBL variant (c.1210 T> C, p.
Michal Bar‐Hakim, Anat Abramovich, Sara Via‐Dorembus, Gali Heimer, Bruria Ben‐Zeev, Etai Adam, Assaf A. Barg, Jonathan Roth, Basheer Sheick‐Yousif, Rony Beeri Berkowiz, Michal Feldon, Haim Bassan, Moran Hausman‐Kedem   +12 more
wiley   +1 more source