Results 31 to 40 of about 47,470 (225)
Randomized placebo-controlled clinical trial of a new chewable formulation of amlodipine for the treatment of hypertension in client-owned cats [PDF]
, 2015 BACKGROUND: There is an unmet clinical need for a cat‐specific formulation of amlodipine to treat hypertensive cats. OBJECTIVES: To assess the efficacy of chewable amlodipine tablets in reducing systolic blood pressure (SBP) in cats diagnosed with ...
Brown +14 more
core +2 more sources
Stereoselective Biotransformation: Transfer of Learning to Advance Drug Metabolism and Biocatalysis
Angewandte Chemie, EarlyView.Understanding stereoselective biotransformations has implications for predicting drug disposition and response and may also inspire novel biocatalytic and biomimetic strategies to address challenges in metabolite and API synthesis. ABSTRACT Chirality is an important determinant of drug action, as enantiomers can exhibit markedly different ...
Grace A. Okunlola, Godwin A. Aleku
wiley +2 more sources
Safety of combination therapy of azilsartan medoxomil and amlodipine: a population-based cohort study [PDF]
Epidemiology and HealthOBJECTIVES This study investigated the safety of azilsartan and amlodipine combination therapy versus other angiotensin receptor blockers (ARBs) and amlodipine in patients with hypertension.
Hyesung Lee +9 more
doaj +1 more source
National Journal of Physiology, Pharmacy and Pharmacology, 2014 Background: The development of newer classes of antiepileptic drugs has created several opportunities for the treatment of epilepsy. Aims & Objective: The present study was designed to assess the$effect of amlodipine on the antiepileptic action of ...
Mohamed Abdelgalil Hassan +1 more
doaj +1 more source
Рациональная фармакотерапия в кардиологии, 2016 Aim. To evaluate efficacy and safety of a new drug of amlodipine – S-amlodipine (Azomex, Emcur, India) compared to original drug of racemic amlodipine (Norvasc, Pfizer, USA) in patients with arterial hypertension (HT) of I-II grade.Material and methods ...
M. A. Maksimova +5 more
doaj +1 more source
Separations, 2023 The main purpose of the current research was to determine the impact of cumin and green tea on the pharmacodynamics and pharmacokinetics of amlodipine in hypertensive rats. Wistar rats were given 40 mg/kg of L-NAME orally every day for two weeks in order
Ibrahim Abdelsalam Abdelrahman +5 more
doaj +1 more source
Generic versus brand-name drugs used in cardiovascular diseases [PDF]
, 2016 This meta-analysis aimed to compare the efficacy and adverse events, either serious or mild/moderate, of all generic versus brand-name cardiovascular medicines.
Boccia, Stefania +9 more
core +1 more source
Effects of curcumin on the pharmacokinetics of amlodipine in rats and its potential mechanism
Pharmaceutical Biology, 2020 Context Hyperlipidaemia and hypertension are often treated together with curcumin and amlodipine. It is necessary to investigate the drug-drug interaction between curcumin and amlodipine.
Na Jiang +3 more
doaj +1 more source
Фармакокинетика и Фармакодинамика, 2022 Introduction. The advantages of fixed-dose combination losartan + amlodipine + rosuvastatin compared to mono-drugs and two-component combinations are to increase the therapeutic efficacy, to reduce the cost of the product and to make the drug easier to ...
A. L. Khokhlov +6 more
doaj +1 more source
Distinguishing hypertension from hypertrophic cardiomyopathy as a cause of left ventricular hypertrophy [PDF]
, 2015 Distinguishing Hypertension From Hypertrophic Cardiomyopathy as aCause of Left Ventricular HypertrophyIn most hypertensive patients, left ventricular (LV) wallthickness is normal or only mildly increased (≤13 ...
Autore, Camillo +4 more
core +1 more source