Results 71 to 80 of about 32,786 (201)

Can adherence to antihypertensive therapy be used to promote adherence to statin therapy?

open access: yesPatient Preference and Adherence, 2009
Richard H Chapman1, Elise M Pelletier1, Paula J Smith1, Craig S Roberts21US Health Economics and Outcomes Research, IMS Health, Falls Church, VA, USA; 2Global Outcomes Research, Pfizer Inc, New York, NY, USAObjective: To compare ...
Richard H Chapman   +3 more
doaj  

The antihypertensive effect of amlodipine in cats [PDF]

open access: yesMedicamentul Veterinar, 2011
The purpose of the study was to evaluate the effect of amlodipine on blood pressure and renal function in cats with arterial hypertension secondary to chronic renal failure.
D. Morar,   +4 more
doaj  

Intrinsic Factors Influencing Simvastatin and Simvastatin Acid Pharmacokinetics: Age‐Related Studies in Thai Adults and Cross‐Population Comparisons

open access: yesClinical and Translational Science, Volume 19, Issue 2, February 2026.
ABSTRACT Intrinsic factors such as age and ethnicity influence statin pharmacokinetics (PK) and may increase the risk of muscle‐related adverse events. This study investigated the effect of age on the PK of simvastatin (SV) and its active metabolite, simvastatin acid (SVA), in healthy Thai subjects using an LC–MS/MS assay while accounting for key ...
Thanate Srimatimanon   +11 more
wiley   +1 more source

Executive Summary of the 2024 Philippine Clinical Practice Guidelines on the Diagnosis and Management of Acute Severe Blood Pressure Elevation

open access: yesThe Journal of Clinical Hypertension, Volume 28, Issue 2, February 2026.
ABSTRACT A recent survey in the Philippines, PRESYON‐4, showed increasing prevalence of hypertension from 22% in the 1990s to 37% in 2021, of which only 52% were aware of their diagnosis. While rates of treatment and adherence were 68% and 86%, respectively, the rate of BP control was low at 37%. Furthermore, there remained a high degree of unawareness
Deborah Ignacia D. Ona   +17 more
wiley   +1 more source

S-amlodipine induces liver inflammation and dysfunction through the alteration of intestinal microbiome in a rat model

open access: yesGut Microbes
S-amlodipine, a commonly prescribed antihypertensive agent, is widely used in clinical settings to treat hypertension. However, the potential adverse effects of long-term S-amlodipine treatment on the liver remain uncertain, given the cautionary ...
Xinxin Liu   +8 more
doaj   +1 more source

Effect of Antihypertensive Treatment on Hypotension, Mortality and Length of Stay in Orthopedic Trauma and First Detected High Blood Pressure Adults in a Large Urban Hospital: A Retrospective Cohort Study

open access: yesThe Journal of Clinical Hypertension, Volume 28, Issue 2, February 2026.
ABSTRACT Trauma is a frequent cause of hospital admission in adults, and while arterial hypertension is common in the general population, reactive hypertension associated with trauma remains poorly studied from a therapeutic perspective. This retrospective cohort study aimed to estimate the impact of antihypertensive treatment on hypotension occurrence,
Carlos José Atencia, Fabian Jaimes
wiley   +1 more source

Effect of Amlodipine on The Concentration of Carotid Tissue Endothelin in High Cholesterol Fed Rabbits

open access: yesپزشکی بالینی ابن سینا, 2008
Introduction & Objective: Endothelin-1 is involved in induction and progression of atherosclerosis. Since several changes with abnormality in transferring of calcium ions have been seen in atherosclerotic vessels, it is supposed that calcium channel ...
Mostafa Mohammadi   +2 more
doaj  

Comparisons of the pharmacokinetics and tolerability of fixed-dose combinations of amlodipine besylate/losartan and amlodipine camsylate/losartan in healthy subjects: a randomized, open-label, single-dose, two-period, two-sequence crossover study

open access: yesDrug Design, Development and Therapy, 2016
YoonJung Choi,1 SeungHwan Lee,2 Sang-Min Cho,3 Won-Ho Kang,3 Kyu-Yeol Nam,4 In-Jin Jang,1 Kyung-Sang Yu1 1Department of Clinical Pharmacology and Therapeutics, Seoul National University College of Medicine, 2Clinical Trials Center, Seoul National ...
Choi Y   +6 more
doaj  

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