Results 71 to 80 of about 70,737 (298)

Impact of Antihypertensive Treatment on Outcomes of Adjuvant Bevacizumab for Ovarian Cancer (IATRO), Results from a Nationwide Emulated Clinical Trial

Clinical Pharmacology &Therapeutics, EarlyView.
Antiangiogenic therapy with bevacizumab improves outcomes in ovarian cancer but induces hypertension, leading to major adverse cardiovascular events (MACE). While calcium channel blockers (CCBs) and angiotensin‐converting enzyme inhibitors (ACEi) are recommended for managing bevacizumab‐associated hypertension, their impacts on cancer progression and ...
Floriane Jochum, Élise Dumas, Joe‐Elie Salem, Stéphane Ederhy, Anne‐Sophie Hamy, Lise Lecointre, Enora Laas, Fabien Reyal, Fabrice Lecuru, Cherif Akladios, Paul Gougis   +10 more
wiley   +1 more source

The Effects of Amlodipine on the Biochemical and Histopathological Changes in the Rabbit Ileum Subjected to Ischemia-Reperfusion

Eurasian Journal of Medicine, 2011
Objective: The aim of this study was to determine the potential, protective effects of amlodipine in an experimental, ischemia-reperfusion (I/R) model in the rabbit small intestine.
A. Kagan Coskun, Armagan Gunal, Zekai Halici, Akgun Oral, Melik Seyrek, Yasin Bayir, Cenk Kilic, Taner Yigit, Tahir Ozer, A. Ihsan Uzar   +9 more
doaj  

Could NICE guidance on the choice of blood pressure lowering drugs be simplified? [PDF]

, 2012
Reecha Sofat and colleagues argue that prescribing advice needs updating in the light of recent evidence that all classes of blood pressure lowering drugs are broadly ...
Casas, Juan P, Grosso, Anthony M, Hingorani, Aroon D, MacAllister, Raymond, Prichard, Brian NC, Smeeth, Liam, Sofat, Reecha   +6 more
core   +2 more sources

Atorvastatin and Fluvastatin Potentiate Blood Pressure Lowering Effect of Amlodipine through Vasorelaxant Phenomenon [PDF]

, 2023
Niaz Ali, Wajid Ali, Abid Ullah, Shujaat Ahmad, Ahad Amer Alsaiari, Mazen Almehmadi, Osama Abdulaziz, Mamdouh Allahyani, Abdulelah Aljuaid   +8 more
openalex   +1 more source

Association Discovery Approach in Healthcare Big Data to Identify Drug Safety and Drug Repurposing Signals

Clinical Pharmacology &Therapeutics, EarlyView.
Data science approaches have been increasingly implemented in healthcare big data to evaluate the safety and effectiveness of drugs. Association discovery is a data mining approach that finds potentially associated elements in high‐dimensional data. We present a novel implementation of the association discovery approach in longitudinal healthcare data ...
George S. Q. Tan, Lynn Miller, Sam Wade, Jenni Ilomäki, Dickson Lukose, Jia Rong, Geoffrey I. Webb   +6 more
wiley   +1 more source

Economic evaluation of olmesartan/amlodipine fixed-dose combination for hypertension treatment in China

Journal of Medical Economics, 2019
Objectives: To evaluate the cost-effectiveness of olmesartan/amlodipine fixed-dose combination vs olmesartan and amlodipine free combination, amlodipine single drug, and valsartan/amlodipine fixed-dose combination in the treatment of hypertensive ...
M. Ren, Dennis Xuan, Y. Lu, Yuyan Fu, J. Xuan   +4 more
semanticscholar   +1 more source

Clinical Implementation of Pharmacogenomics and Drug–Drug Interaction Screening in a German Academic Teaching Hospital and Outpatient Follow‐Up

Clinical Pharmacology &Therapeutics, EarlyView.
Overview of the implemented pharmacogenomics (PGx) process in clinical routine at the Robert Bosch Hospital: from patient enrollment via the hospital information system, DNA detection using a customized TaqMan OpenArray panel and qPCR for CNV assessment, to clinical translation of genotyping results into PGx guideline‐based recommendations using a ...
Roman Tremmel, Filippa Schreeck, Simon Jaeger, Severin Schricker, Elke Schaeffeler, Svitlana Igel, Daniela Steinberger, Manuel Pagitz, Jörg Latus, Markus Ketteler, Kerstin Bühl, Marc‐H. Dahlke, Hans‐Georg Kopp, Matthias Schwab   +13 more
wiley   +1 more source

Loading Amlodipine on Diamond Nanoparticles: A Novel Drug Delivery System

Nanotechnology, Science and Applications, 2019
Background Diamond nanoparticles (Nanodiamond) are biocompatible drug delivery platforms with outstanding surface properties. Their passage into the brain has been confirmed previously.
Shawqi H Alawdi, H. Eidi, M. M. Safar, M. ABDEL-WAHHAB   +3 more
semanticscholar   +1 more source

Medication adherence in patients with acutely decompensated heart failure: A cross‐sectional study in the emergency department (ADHF‐ED)

European Journal of Heart Failure, EarlyView.
The ADHF‐ED trial. ADHF, acutely decompensated heart failure; CHF, chronic heart failure; ED, emergency department; EF, ejection fraction; MRA, mineralocorticoid receptor antagonist; NT‐proBNP, N‐terminal pro‐B‐type natriuretic peptide. Created with the support of AI (ChatGPT).
Michael Kunz, Juel Maalouli Schaar, Katharina R. Welker, Lucas Lauder, Felix Götzinger, Ingrid Kindermann, Martin Schulz, Michael Böhm, Markus R. Meyer, Felix Mahfoud   +9 more
wiley   +1 more source

Amlodipine improves symmetric dimethylarginine in dogs with chronic kidney disease

Frontiers in Veterinary Science
IntroductionIn canines, chronic kidney disease (CKD) is frequently associated with high blood pressure. Amlodipine is used to treat hypertension in dogs, and we anticipated that amlodipine administration might improve renal function in dogs. However, the
Shohei Morita, Youhei Mochizuki, Takahiro Kondo, Yasuyoshi Matsuda, Takahiro Ohmori, Aritada Yoshimura, Ryuji Fukushima   +6 more
doaj   +1 more source