Results 1 to 10 of about 8,237 (118)

Simultaneous determination of indapamide, perindopril and perindoprilat in human plasma or whole blood by UPLC-MS/MS and its pharmacokinetic application

Journal of Pharmaceutical Analysis, 2018
Simple and sensitive methods were developed for the determination of indapamide, perindopril and its active metabolite perindoprilat in human plasma or whole blood by hyphenated ultra-performance liquid chromatography-mass spectrometry (UPLC-MS/MS ...
Min Song, Tai-Jun Hang
exaly   +3 more sources

Pharmacovigilance and clinical insights into perindopril-induced thrombocytopenia: a case report of diagnostic challenges and therapeutic alternatives [PDF]

The Egyptian Heart Journal
Introduction and objectives Perindopril-induced thrombocytopenia is a rare but potentially serious adverse drug reaction. It remains underrecognized in clinical practice, particularly in elderly patients with cardiovascular disease.
Mochamad Faishal Riza, Samuel Sudanawidjaja, Ronald Torang Marsahala Panggabean, Isnaini Isnaini, Lely Puspita Candra Dewi, Andrianus Oktovianto, Deo Idarto, Vincent Aurelius Gonaldy, Alamanda Sofania, Marselina Marselina   +9 more
doaj   +2 more sources

Melatonin combination with perindopril alleviated doxorubicin cardiac toxicity in L-NAME hypertensive rats: comparative study with perindopril [PDF]

Ain Shams Journal of Forensic Medicine and Clinical Toxicology, 2020
Introduction: Doxorubicin is a highly effective anticancer agent with serious cardiotoxic effects. Hypertension is considered as a major risk factor for doxorubicin cardiotoxicity.
Mona Raafat, Amany Hasanin, Ahmed Badawy, Takwa Salam, Wesam El-Bakly   +4 more
doaj   +1 more source

Practical use of single pill combinations in the treatment of hypertension — an analysis focused on perindopril-based combinations

Arterial Hypertension, 2023
Hypertension (HTN) is a major modifiable cardiovascular risk factor. Despite availability of effective blood pressure-lowering medications, HTN remains poorly controlled.
Aleksander Prejbisz, Piotr Dobrowolski, Adrian Doroszko, Krzysztof J. Filipiak, Andrzej Januszewicz, Agnieszka Olszanecka, Krzysztof Narkiewicz, Andrzej Tykarski, Jacek Wolf   +8 more
doaj   +1 more source

COMPARISON OF ENALAPRIL AND PERINDOPRIL IN PATIENTS WITH ARTERIAL HYPERTENSION AND LEFT VENTRICLE SYSTOLIC DYSFUNCTION

Рациональная фармакотерапия в кардиологии, 2016
Aim. To compare efficacy of enalapril and perindopril in patients with arterial hypertension (HT) and left ventricle systolic dysfunction.Material and methods.
Yu. I. Grinshtein, O. L. Barbarash, D. A. Yakhontov, A. E. Popelysheva, V. V. Shabalin, N. B. Osetrova   +5 more
doaj   +1 more source

Potential pharmacokinetic interactions in fixed-dose combinations of perindopril/indapamide/amlodipine compared with perindopril/indapamide and amlodipine in healthy Chinese volunteers

Acta Materia Medica, 2023
S05590 is a fixed-dose combination of perindopril tert-butylamine 4 mg/indapamide 1.25 mg, and S06593 is a fixed-dose combination of perindopril arginine 5 mg/indapamide 1.25 mg/amlodipine 5 mg.
Huitao Gao, Hongzhong Liu, Xin Zheng, Xinge Cui, Stephanie Bricout-Hennel, Arnaud Lucien, Pauline Lauruol, Yaqin Wang, Xue Wang, Hongyun Wang, Chen Rui   +10 more
doaj   +1 more source

The effect of age on blood pressure response by 4‐week treatment perindopril: A pooled sex‐specific analysis of the EUROPA, PROGRESS, and ADVANCE trials

Clinical and Translational Science, 2021
Previous studies showed that postmenopausal women are more likely to have poorly controlled hypertension than men of the same age. Whether this is caused by inadequate treatment or poor response to antihypertensive agents remains unknown. The aim of this
Michelle M. Schreuder, Katrina M. Mirabito Colafella, Eric Boersma, Jasper J. Brugts, Jeanine E. Roeters van Lennep, Jorie Versmissen   +5 more
doaj   +1 more source

Perindopril/amlodipine-induced thrombotic microangiopathy

Turkish Journal of Emergency Medicine, 2021
This is the first report on a case of perindopril/amlodipine-induced thrombotic microangiopathy (TMA) syndrome. A 48-year-old female was admitted complaining of nettle rash all over the body, bloody urine, and weakness shortly after starting ...
Vlatka Perisa, Dorian Laslo, Lana Maričć, Lada Zibar   +3 more
doaj   +1 more source

Preliminary Consequences of Blood Pressure Management and Blood Homocysteine Levels with Perindopril in Newly Diagnosed Hypertensive Patients in the Vietnamese Population

International Journal of Hypertension, 2023
Background. Perindopril is an ACE inhibitor that aids in both blood pressure regulation and homocysteine reduction. Objectives. Our study aimed to evaluate the results of controlling blood pressure and blood homocysteine levels by perindopril in patients
Son Kim Tran, An Bao Truong, Phi Hoang Nguyen, Toan Hoang Ngo, Tuyen Long Vu, Khoa Dang Dang Tran, Phuong Minh Vo, Bao The Nguyen, Tuong Le Trong Huynh, Kien Trung Nguyen, Hung Do Tran   +10 more
doaj   +1 more source

Zero crossing and ratio spectra derivative spectrophotometry for the dissolution tests of amlodipine and perindopril in their fixed dose formulations

Current Issues in Pharmacy and Medical Sciences, 2014
Dissolution tests of amlodipine and perindopril from their fixed dose formulations were performed in 900 mL of phosphate buffer of pH 5.5 at 37°C using the paddle apparatus.
Maczka Paulina, Gumieniczek Anna, Galeza Justyna, Pietras Rafal   +3 more
doaj   +1 more source