Results 41 to 50 of about 10,576 (193)

Updated EAACI Statement on Drug Hypersensitivity Skin Testing: Methodology and Non‐Irritative Concentrations

open access: yesAllergy, EarlyView.
ABSTRACT These updated EAACI guidelines aim to standardize skin testing methodologies for both immediate and non‐immediate drug hypersensitivity reactions. For immediate reactions, the optimal testing window is 4–6 weeks post‐reaction; whereas beyond 6 months, false‐negative results increase.
Annick Barbaud   +14 more
wiley   +1 more source

Heart failure medication to prevent cancer therapy–related cardiac dysfunction: A narrative review

open access: yesBritish Journal of Pharmacology, EarlyView.
Advances in oncological therapies have improved cancer survival but also have increased the clinical incidence of cancer therapy–related cardiac dysfunction (CTRCD), a spectrum of conditions ranging from subclinical biomarker or strain abnormalities to progressive heart failure and cardiogenic shock.
Fabian Voß   +3 more
wiley   +1 more source

Perindopril arginine: a new ACE inhibitor salt increases therapeutic potential

open access: yesКардиоваскулярная терапия и профилактика, 2008
Perindopril is one of the most effective ACE inhibitors used for cardiovascular disease treatment. At the moment, perindopril is used as perindopril tert butylamine with limited "shelf life"; the medication should be specially packed for the countries ...
Yu. A. Karpov
doaj  

Semaglutide in type 2 diabetes and chronic kidney disease in Australia: practical clinical considerations from a multidisciplinary panel

open access: yesInternal Medicine Journal, EarlyView.
Abstract Chronic kidney disease (CKD) and cardiovascular disease (CVD) are major causes of morbidity and mortality in people with type 2 diabetes (T2D). Contemporary CKD guidelines increasingly support incorporation of glucagon‐like peptide‐1 receptor agonists (GLP‐1RAs) as an additional pillar of cardiorenal therapy alongside renin–angiotensin ...
Eugenia Pedagogos   +5 more
wiley   +1 more source

The effects of uninterrupted and interrupted sitting on blood pressure and arterial stiffness in patients with established coronary heart disease

open access: yesExperimental Physiology, EarlyView.
Abstract Sedentary behaviour is an independent risk factor for cardiovascular disease. In healthy adults, prolonged uninterrupted sitting acutely increases blood pressure (BP) and aortic stiffness; however, these effects can be mitigated with light physical activity interruptions.
Simon Fryer   +7 more
wiley   +1 more source

Comparison of endothelial function in patients with Stage I-II arterial hypertension and stable angina, receiving various bradycardic agents and perindopril

open access: yesКардиоваскулярная терапия и профилактика, 1970
Aim. To compare endothelial function in patients with Stage I-II arterial hypertension (AH) and Functional Class (FC) II stable angina, receiving either beta-adrenoblocker (metoprolol tartrate) or If channel inhibitor (ivabradine), combined with ...
L. L. Kirichenko   +5 more
doaj  

Angiotensin‐converting enzyme and exercise adaptations: Genetic variability, pharmacological modulation and future directions

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend ACE I/D genotype, enzyme activity and integrated physiological adaptations. Upper panel: Conceptual framework linking the ACE I/D polymorphism (left) with circulating/tissue ACE activity (centre; violin plots based on hypothetical data for illustration) and strength/power versus endurance phenotypes (right).
Tórur Sjúrðarson   +1 more
wiley   +1 more source

A Quantitative Analysis of Street‐Level Drugs Seized in New South Wales, Australia: Purity, Dose and Adulterants

open access: yesDrug and Alcohol Review, Volume 45, Issue 7, November 2026.
ABSTRACT Introduction The Combined Surveillance and Monitoring of Seized Samples (CoSMoSS) program is a joint harm reduction initiative between NSW Health and NSW Police Force. Here, we examine the contents and purity of a sample of seized suspected target drugs (cocaine, heroin, methamphetamine and 3,4‐methylenedioxymethamphetamine ‘MDMA’).
Janette L. Smith   +7 more
wiley   +1 more source

Perindopril sensitizes hepatocellular carcinoma to chemotherapy: A possible role of leptin / Wnt/ β-catenin axis with subsequent inhibition of liver cancer stem cells

open access: yesSaudi Pharmaceutical Journal, 2022
Hepatocellular carcinoma (HCC) is one of the leading causes of cancer-related death. The major challenge in managing HCC is the resistance to chemotherapy.
Sherin Zakaria   +2 more
doaj   +1 more source

Perindopril in Breast Milk and Determination of Breastfed Infant Exposure: A Prospective Observational Study

open access: yesDrug Design, Development and Therapy, 2020
Catherine Leggett,1,* Ei Mon Phyo Lwin,2,* Usha Ritchie,1 Yunmei Song,2 Jacobus P Gerber,2 Sean Turner,1 William M Hague,3,4 Michael Stark,3,5 Richard Upton,2 Sanjay Garg2 1SA Pharmacy, Women’s and Children’s Hospital, North Adelaide, SA 5006,
Leggett C   +9 more
doaj  

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