Results 41 to 50 of about 3,552 (228)

Ammonia Detoxification Inhibits Liver Metastasis by Reshaping Hepatic Microenvironment

Advanced Science, EarlyView.
Liver metastasis diverts aspartate into hyperactive pyrimidine synthesis, disrupting urea cycling and causing pathogenic ammonia accumulation. Ammonia dually reprograms the microenvironment by: (1) activating hepatic stellate cells (HSCs) into pro‐fibrotic metastasis‐associated fibroblasts (MAFs), and (2) suppressing anti‐tumor monocytes/macrophages ...
Sumin Sun, Haili Hu, Long Chen, Yuan Gao, Peng Sun, Liming Chen   +5 more
wiley   +1 more source

Food-Like Growth Conditions Support Production of Active Vitamin B12 by Propionibacterium freudenreichii 2067 without DMBI, the Lower Ligand Base,or Cobalt Supplementation [PDF]

, 2017
Propionibacterium freudenreichii is a traditional dairy bacterium and a producer of short chain fatty acids (propionic and acetic acids) as well as vitamin B12.
Chamlagain, Bhawani, Deptula, Paulina, Edelmann, Minnamari, Nyman, Tuula A., Piironen, Vieno, Sangsuwan, Panchanit, Savijoki, Kirsi, Varmanen, Pekka   +7 more
core   +1 more source

Cotton Recruits Soil‐Derived Delftia tsuruhatensis to Suppress Aphid Detoxification Via Salicylic Acid‐Mediated Defense

Advanced Science, EarlyView.
This study systematically reveals a complex interactive network involving plants, microbes, and insects, elucidating the ecological and molecular mechanisms by which cotton enhances its resistance to aphids through the active recruitment of the beneficial soil bacterium Delftia tsuruhatensis.
Hui Xue, Fengchao Diao, Qiqing Yu, Xiangzhen Zhu, Tingfang Zhong, Li Wang, Kaixin Zhang, Dongyang Li, Jichao Ji, Junyu Luo, Jinjie Cui, Xueke Gao   +11 more
wiley   +1 more source

Quantitative RT-PCR analysis of differentially expressed genes in Quercus suber in response to Phytophthora cinnamomi infection [PDF]

, 2014
cDNA-AFLP methodology was used to gain insight into gene fragments differentially present in the mRNA profiles of Quercus suber roots infected with zoospores of Phytophthora cinnamomi at different post challenge time points.
A Chandra, A Kohler, A Muller-Taubenberger, A Stintzi, AC Coelho, ACM Moreira-Marcelino, AE Frolov, AF Schlumbaum, AJ Vigers, B Venkatesh, BC Meyers, BC Meyers, BJC Cornelissen, C Ainsworth, C Brasier, C Lamb, C Plomion, C Vieira Dos Santos, CC Nwugo, CF Nathan, CM Brasier, CP Selitrennikoff, CP Woloshuk, CW Bachem, DB Neale, ES Bachman, F Kurth, F Mauch, FM Ausubel, G Leubner-Metzger, G Leubner-Metzger, G Schmidt, HJM Linthorst, J Garin, J Grenier, J Sambrook, J Soriano, JC Mills, JD Jones, JD Robertus, JE Rookes, JG Pausas, JK Young, JM Hinch, JP Wubben, JV Die, JV Die, JV Natividade, K Broglie, K Sharma, KE Hammond-Kosack, L Chen, L Marum, L Sun, LC Van Loon, LH Robinson, M Expósito-Rodríguez, M Horta, M Migocka, M Sebastiana, M Xu, M Zabeau, MH Asif, MT Tarkka, N Benhamou, N Dudareva, NJ Walker, NS Coll, NV Demidenko, O Augusto, O Radwan, P Baptista, P Breyne, P Caetano, P Leone, PB Hoj, R Ghosh, R Ingle, R Milcevicova, RX Yan, S Ray, S Rozen, S Shuman, S Uknes, SF Altschul, SH Hulbert, T Jung, T Money, U Gubler, U Gubler, Y Habu, YJ Kim, ZG Tong   +92 more
core   +2 more sources

Developmental and Phenotypic Outcomes in Mild Phenylalanine Hydroxylase Deficiency

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Benign hyperphenylalaninemia (bHPA) is defined as elevated phenylalanine (Phe) levels remaining ≤ 360 μmol/L (6 mg/dL) and not requiring medical intervention. Individuals with bHPA may demonstrate a rise in their Phe levels > 360 μmol/L, effectively developing a mild PKU phenotype requiring therapy to prevent neurocognitive complications. This
Aaron Williams, Kristian Divin, Lindsay C. Burrage, William J. Craigen, Fernando Scaglia, Claudia Soler‐Alfonso, V. Reid Sutton, Kevin E. Glinton, Ronit Marom   +8 more
wiley   +1 more source

The necrotrophic effector protein SnTox3 re-programs metabolism and elicits a strong defence response in susceptible wheat leaves [PDF]

, 2016
BACKGROUND: The fungus Stagonospora nodorum is a necrotrophic pathogen of wheat. It causes disease by secreting proteinaceous effectors which interact with proteins encoded by dominant susceptibility genes in the host.
Care, Natasha, Du Fall, Lauren A., Molloy, Mark, Ohms, Stephen J, Pascovici, Dana, Solomon, Peter S., Song, Xiaomin, Winterberg, Britta   +7 more
core   +1 more source

Új sztereoszelektív biokatalitikus folyamatok és biokatalizátorok = Novel stereoselective biocatalytical processes and biocatalysts [PDF]

, 2010
Napjainkban az egyik legnagyobb kémiai kihívás a biológiailag aktív anyagok gazdaságos szintézise. Egyre nagyobb az igény a sztereoizomerek - pl. a királis anyagok adott enantiomerjének - tiszta formában történő előállítására.
Bódai, Viktória, Novák, Lajos, Paizs, Csaba, Pilbák, Sarolta, Poppe, László, Rétey, János, Szakács, György, Toke, Eniko Rita   +7 more
core  

Transcriptomic characterization of two major Fusarium resistance quantitative trait loci (QTLs), Fhb1 and Qfhs.ifa-5A, identifies novel candidate genes [PDF]

, 2013
Fusarium head blight, caused by Fusarium graminearum, is a devastating disease of wheat. We developed near-isogenic lines (NILs) differing in the two strongest known F.
Adam, G. (Gerhard), Ametz, Christian, Berthiller, Franz, Buerstmayr, Hermann, Jia, Haiyan, Kreil, David, Lemmens, Marc, Muehlbauer, Gary J., Schweiger, W. (Wolfgang), Siegwart, Gerald, Steiner, B. (Barbara), Wiesenberger, Gerlinde   +11 more
core   +1 more source

Styrene Production in Genetically Engineered Escherichia coli in a Two-Phase Culture

BioTech
Styrene is an important industrial chemical. Although several studies have reported microbial styrene production, the amount of styrene produced in batch cultures can be increased.
Shuhei Noda, Ryosuke Fujiwara, Yutaro Mori, Mayumi Dainin, Tomokazu Shirai, Akihiko Kondo   +5 more
doaj   +1 more source

Heteroconium chaetospira induces resistance to clubroot via upregulation of host genes involved in jasmonic acid, ethylene, and auxin biosynthesis.

PLoS ONE, 2014
An endophytic fungus, Heteroconium chaetospira isolate BC2HB1 (Hc), suppressed clubroot (Plasmodiophora brassicae -Pb) on canola in growth-cabinet trials.
Rachid Lahlali, Linda McGregor, Tao Song, Bruce D Gossen, Kazuhiko Narisawa, Gary Peng   +5 more
doaj   +1 more source