Results 91 to 100 of about 47,514 (190)

Igfbp2 Downregulation in PVT‐CeA Glutamatergic Circuits Drives Neonatal Anesthesia‐Induced Fear Memory Deficits

Advanced Science, Volume 12, Issue 41, November 6, 2025.
Repeated neonatal sevoflurane exposure impairs adolescent fear memory through Igfbp2 downregulation in paraventricular thalamus‐central amygdala glutamatergic projections. Restoring Igfbp2 or activating this circuit rescues memory deficits, neuronal excitability, and spine density, identifying a precise molecular target for preventing anesthesia ...
Weiming Zhao, Ke Peng, Baojian Zhao, Xiaowen Meng, Gang Wang, Hanbing Xu, Li Deng, Xisheng Shan, Yichan Wang, Qiya Xu, Yanan Gao, Ruixia Weng, Hong Liu, Jin Tao, Huayue Liu, Shaoyong Song, Fuhai Ji   +16 more
wiley   +1 more source

Psychogenic amnesia: syndromes, outcome, and patterns of retrograde amnesia [PDF]

, 2017
There are very few case series of patients with acute psychogenic memory loss (also known as dissociative/functional amnesia), and still fewer studies of outcome, or comparisons with neurological memory-disordered patients.
Casey, Sarah J, Corno, Federica, Friedner, Kimberley, Harrison, Neil A, Humphreys, Kate, Jaldow, Eli Joseph, Johnston, Kate, Kopelman, Michael D, Pitkanen, Mervi   +8 more
core   +1 more source

Transient epileptic amnesia

Neurologijos seminarai, 2018
Transient epileptic amnesia is an adult onset form of temporal epilepsy which is characterised by recurrent acute seizure-induced amnesia often accompanied by ongoing memory disturbances of autobiographical, topographical amnesia and accelerated long ...
J. S. Anužytė , G. Rutkauskaitė , R. Mameniškienė   +2 more
doaj   +1 more source

Modeling presynaptic inhibition by the amyloid precursor protein demonstrates one potential mechanism for preventing runaway synaptic modification in Alzheimer's disease

Alzheimer's &Dementia, Volume 21, Issue 10, October 2025.
Abstract INTRODUCTION Previous simulations of Hebbian associative memory models inspired the malignant synaptic growth hypothesis of Alzheimer's disease (AD), which suggests that cognitive impairments arise due to runaway synaptic modification resulting from poor separation between encoding and retrieval.
Dylan Barber, Michael E. Hasselmo, Heather C. Rice   +2 more
wiley   +1 more source

Evaluation of the Sedative Activity of Naringenin: In Vivo Study with Pharmacokinetics and Molecular Docking Insights

ChemistryOpen, Volume 14, Issue 10, October 2025.
The study investigates the sedative potential of naringenin (NAR) through in vivo and in silico approaches. NAR significantly enhances sleep duration and reduces latency in mice, especially when combined with diazepam. Molecular docking shows strong binding to GABAA receptors, suggesting a GABAergic mechanism.
Dipu Bishwas, Md. Shimul Bhuia, Salehin Sheikh, Mohammed Alfaifi, Abdul Malik, Nikhat J. Siddiqui, Divya Jain, Mehedi Hasan Bappi, Muhammad Torequl Islam   +8 more
wiley   +1 more source

Bilateral Hippocampal Infarction as Etiology of Sudden and Prolonged Memory Loss

Case Reports in Neurology, 2012
Sudden memory loss, with prolonged cognitive deterioration, clinically initially resembling a transitory global amnesia (TGA)-like episode, might be caused by ischemic stroke in the hippocampal regions.
Ivan Marinkovic, Jukka Lyytinen, Leena Valanne, Riikka Niinikuru, Eero Pekkonen   +4 more
doaj   +1 more source

Alcohol-induced retrograde facilitation renders witnesses of crime less suggestible to misinformation [PDF]

, 2017
RATIONALE: Research has shown that alcohol can have both detrimental and facilitating effects on memory: intoxication can lead to poor memory for information encoded after alcohol consumption (anterograde amnesia) and may improve memory for information ...
A Hagsand, AC Moss, AJ Caswell, AJ Harvey, AM Ridley, Anne M. Ridley, CW Mueller, D Crossland, Edit Barnoth, EF Loftus, EF Loftus, ES Parker, ES Parker, F Gabbert, GH Gudjonsson, H Blank, Ian P. Albery, J Ost, J Shaw, J Weafer, J Weafer, Jack Young, JC Yuille, JR Evans, JT Wixted, JT Wixted, Julie Gawrylowicz, JW Schooler, K Van Oorsouw, K Van Oorsouw, KR Bruce, L Bègue, M McCloskey, MK Johnson, MT Fillmore, MT Fillmore, N Schreiber Compo, P Santtila, P Santtila, PL Moulton, PT Hertel, R Horry, RR Wetherill, SA Maisto   +43 more
core   +2 more sources

Median effective dosage of midazolam oral solution for preschool children in preoperative sedation

Ibrain, Volume 11, Issue 3, Page 385-392, Fall 2025.
This study aimed to detect median effective dosage (ED50) of midazolam oral solution (MOS) for preschool children in preoperative sedation. Thirty children who were scheduled for elective of the hidden penis correction surgery under general anesthesia in the pediatric surgery department were selected.
Rui Jiang, De‐Chuan Wang, Nan Zhao, Ke An, Yi‐Nan Zhang, Zhao‐Qiong Zhu   +5 more
wiley   +1 more source

Transient Global Amnesia with Reversible White Matter Lesions: A Variant of Posterior Reversible Encephalopathy Syndrome?

Case Reports in Neurological Medicine, 2015
Transient global amnesia (TGA) is a self-limited disease characterized by isolated amnesia, which resolves within 24 h. In contrast, posterior reversible encephalopathy syndrome (PRES) is a potentially life-threatening disease that usually presents with ...
Tomoki Nakamizo, Ippei Tsuzuki, Takashi Koide   +2 more
doaj   +1 more source

Sports-related brain injury in the general population: An epidemiological study [PDF]

, 2014
Objectives To determine the incidence, nature and severity of all sports-related brain injuries in the general population. Design Population-based epidemiological incidence study.
Dowell, Tony, Feigin, Valery L., Hume, Partia A., Kahan, Michael, McPherson, Kathryn, Starkey, Nicola J., Theadom, Alice   +6 more
core   +2 more sources