Results 181 to 190 of about 42,817 (291)

Transcranial Direct Current Stimulation (tDCS) for the Treatment of Hemolacria Comorbid With Psychiatric and Somatic Symptoms: A Case Report

open access: yesClinical Case Reports, Volume 14, Issue 6, June 2026.
ABSTRACT Hemolacria is a rare condition characterized by bloody tears. Its etiology is often multifactorial, but functional/psychosomatic mechanisms have been proposed when organic causes are excluded. A 48‐year‐old woman with a history of multiple traumatic brain injuries (coma in 2008, car accident in 2017) presented with refractory generalized ...
Roghayeh Mohammadi, Ahmad Alipour
wiley   +1 more source

Tramiprosate, the Active Agent of ALZ‐801, Modulates Amyloidogenic APP Processing and Tau Phosphorylation in a Cellular Model of Alzheimer's Disease

open access: yesDrug Development Research, Volume 87, Issue 4, June 2026.
ABSTRACT ALZ‐801, a valine‐conjugated prodrug of tramiprosate, has recently been evaluated in a Phase III trial as a potential Alzheimer's disease (AD)‐modifying therapy. Tramiprosate reduces misfolding of amyloid beta (Aβ) monomers and inhibits oligomer formation. In the present study, we investigated tramiprosate's effects on amyloidogenic processing
Kevser Biberoglu, Ozden Tacal
wiley   +1 more source

Triglyceride–Glucose–Waist‐to‐Weight Index: Novel Biomarker for Mild Cognitive Impairment in Older People With Sarcopenic Obesity

open access: yesJournal of Cachexia, Sarcopenia and Muscle, Volume 17, Issue 3, June 2026.
ABSTRACT Background Sarcopenic obesity (SO) is closely associated with mild cognitive impairment (MCI). However, traditional body composition‐based diagnostic criteria for SO fail to adequately incorporate insulin resistance, a key pathophysiological mechanism.
Yue Xing   +5 more
wiley   +1 more source

The Role of Magnetic Resonance Spectroscopy (MRS), Diffusion‐Tensor‐Imaging (DTI) and Structural MRI in the Alzheimer's Disease and Mild Cognitive Impairment Diagnosis: A Review

open access: yesJournal of Magnetic Resonance Imaging, Volume 63, Issue 6, Page 1509-1545, June 2026.
ABSTRACT Alzheimer's disease (AD) is one of the most common neurological disorders affecting older adults, with approximately 7.2 million cases only in the United States. This number is projected to increase to 13.8 million in the United States by 2060, leading to increased expenditures for healthcare, long‐term care and hospice services. Consequently,
Valentina Zecca   +3 more
wiley   +1 more source

Testing the factor structure of the International Trauma Questionnaire in a sample of violence‐exposed women living in Northern Ireland

open access: yesJournal of Traumatic Stress, Volume 39, Issue 3, Page 413-425, June 2026.
Abstract The International Trauma Questionnaire (ITQ) assesses posttraumatic stress disorder (PTSD) and the disturbances in self‐organization (DSO) aspect of complex PTSD (CPTSD) per the ICD‐11. This study examined the ITQ's factor structure among violence‐ or abuse‐exposed women in Northern Ireland, a region with a history of conflict (i.e., “the ...
Marcin Owczarek   +5 more
wiley   +1 more source

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