Results 201 to 210 of about 50,007 (304)

Outcomes reported in interventional studies for mild cognitive impairment: a scoping umbrella review to inform core outcome set development

open access: yesAlzheimer's &Dementia, Volume 22, Issue 9, September 2026.
Abstract There is currently no consensus on the most important treatment outcomes in patients with mild cognitive impairment (MCI). As part of developing a core outcome set for MCI, we conducted a pragmatic scoping umbrella review to summarize outcomes reported in previous studies.
Victoria Grace Gabb   +12 more
wiley   +1 more source

Long-term medical and psychosocial vulnerability after home return following severe traumatic brain injury. [PDF]

open access: yesJ Rehabil Med
Calderone A   +8 more
europepmc   +1 more source

Tau‐associated neuronal loss in the intermediate nucleus of the human hypothalamus, a putative VLPO analog, in progressive supranuclear palsy and Alzheimer's disease

open access: yesAlzheimer's &Dementia, Volume 22, Issue 9, September 2026.
Abstract BACKGROUND Sleep phenotypes differ in progressive supranuclear palsy (PSP) and Alzheimer's disease (AD). The human intermediate nucleus (IntN), a putative ventrolateral preoptic analog, promotes non‐rapid eye movement (NREM) sleep, but its disease‐specific vulnerability is unclear. METHODS Post mortem hypothalami (n = 30; baseline [Braak stage
Shima Rastegar‐Pouyani   +14 more
wiley   +1 more source

Distinct single‐nucleus RNA‐seq changes among non‐neuronal cells in ADNC, LATE‐NC, and mixed pathologies

open access: yesAlzheimer's &Dementia, Volume 22, Issue 9, September 2026.
Abstract INTRODUCTION Limbic‐predominant age‐related transactive response DNA binding protein 43 kDa encephalopathy neuropathological change (LATE‐NC) frequently co‐occurs with Alzheimer's disease neuropathologic change (ADNC), complicating classification.
Qi Qiao   +9 more
wiley   +1 more source

Does classical semiology ("5As") predict post-operative seizure outcome in patients with temporal lobe epilepsy? [PDF]

open access: yesEpileptic Disord
Radhakrishnan A   +10 more
europepmc   +1 more source

Operationalizing Alzheimer's disease trials in the era of targeted therapies

open access: yesAlzheimer's &Dementia, Volume 22, Issue 9, September 2026.
Abstract The therapeutic landscape of Alzheimer's disease (AD) is rapidly evolving with the clinical adoption of anti‐amyloid monoclonal antibodies (mAbs) despite an incomplete understanding of disease mechanisms, progression, and heterogeneity. Designing both observational longitudinal cohorts and clinical trials with novel mAbs in mind is imperative.
Jagan A. Pillai   +12 more
wiley   +1 more source

Dissecting medial temporal lobe from diencephalic sub-volumes: The amnesia dichotomy revisited. [PDF]

open access: yesImaging Neurosci (Camb)
Soussi C   +10 more
europepmc   +1 more source

MARBLE: An in vivo MRI marker of limbic‐predominant age‐related TDP‐43 encephalopathy neuropathologic change (LATE‐NC)

open access: yesAlzheimer's &Dementia, Volume 22, Issue 9, September 2026.
Abstract INTRODUCTION Limbic‐predominant age‐related transactive response DNA binding protein 43 kDa encephalopathy neuropathologic change (LATE‐NC) is common in older adults, yet definitive diagnosis is only possible at autopsy. METHODS This work developed a fully automated in vivo marker of LATE‐NC named MARBLE (MARker of Brain LatE) by applying ...
Mahir Tazwar   +8 more
wiley   +1 more source

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