Results 221 to 230 of about 64,470 (350)

Neuroinflammation demonstrated by 11C‐ER176 PET with amyloid and tau pathology

open access: yesAlzheimer's &Dementia, Volume 22, Issue 1, January 2026.
Abstract INTRODUCTION Understanding neuroinflammation across the Alzheimer's disease (AD) spectrum is essential to elucidate disease mechanisms and individualize therapy. METHODS Human microglial translocator protein (TSPO) expression under inflammatory stimuli was assessed by immunoblot experiments.
Mahathi Kandimalla   +17 more
wiley   +1 more source

Attention-Deficit/Hyperactivity Disorder Following Mild Traumatic Brain Injury in Children: A Retrospective Exploratory Study. [PDF]

open access: yesCureus
Astigarraga Baez JM   +9 more
europepmc   +1 more source

Evaluation of ASC as a therapeutic target for Alzheimer's disease

open access: yesAlzheimer's &Dementia, Volume 22, Issue 1, January 2026.
Abstract Neuroinflammation is increasingly recognized as a central contributor to the pathogenesis and progression of Alzheimer's disease (AD). The apoptosis‐associated speck‐like protein containing a CARD (ASC), encoded by the PYCARD gene, plays a critical role in the formation of multiple inflammasomes, including NLRP3, a key mediator of inflammation
W. Brent Clayton   +12 more
wiley   +1 more source

Overnight sleep affects the stability of neuropsychological classification in mild cognitive impairment

open access: yesAlzheimer's &Dementia, Volume 22, Issue 1, January 2026.
Abstract INTRODUCTION Reversion to normal cognition in mild cognitive impairment (MCI) is relatively common. This study tested whether total sleep time (TST) and sleep efficiency (SE) on the night before cognitive testing predicts MCI reversion. METHODS Fifty‐eight community‐dwelling older adults with MCI (mean age = 75 years) participated.
Jun Ha Chang   +4 more
wiley   +1 more source

Alpha‐synuclein quantitative seed amplification assay predicts conversion to dementia

open access: yesAlzheimer's &Dementia, Volume 22, Issue 1, January 2026.
Abstract INTRODUCTION The alpha‐synuclein seed amplification assay (SAA) has shown excellent performance in the detection of Lewy body pathology in cerebrospinal fluid (CSF). Lewy body pathology is prognostically relevant in patients at risk for dementia. Current assays only provide binary results, so there is a need to quantify the extent of pathology
Stefan Bräuer   +37 more
wiley   +1 more source

Proactive Privacy Amnesia for Large Language Models: Safeguarding PII with Negligible Impact on Model Utility [PDF]

open access: green
Martin Kuo   +11 more
openalex   +1 more source

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