Results 11 to 20 of about 44,340 (376)

The Preparation and Clinical Efficacy of Amnion-Derived Membranes: A Review

Journal of Functional Biomaterials, 2023
Biological tissues from various anatomical sources have been utilized for tissue transplantation and have developed into an important source of extracellular scaffolding material for regenerative medicine applications.
Alison L. Ingraldi, Robert G. Audet, Aaron J. Tabor   +2 more
doaj   +2 more sources

Single cell transcriptomic analysis of human amnion identifies cell-specific signatures associated with membrane rupture and parturition

Cell & Bioscience, 2022
Background The human amnion is an intrauterine tissue which is involved in the initiation of parturition. In-depth understanding of gene expression signatures of individual cell types in the amnion with respect to membrane rupture at parturition may help
Wang-Sheng Wang, Yi-Kai Lin, Fan Zhang, Wen-Jia Lei, Fang Pan, Ya-Nan Zhu, Jiang-Wen Lu, Chu-Yue Zhang, Qiong Zhou, Hao Ying, Kang Sun   +10 more
doaj   +2 more sources

The Influence of the Preservation Method and Gamma Irradiation Sterilization on TGF-β and bFGF Levels in Freeze-Dried Amnion Membrane (FD-AM) and Amnion Sponge

International Journal of Biomaterials, 2021
Background. Amnion grafts can be preserved as freeze-dried amnion membrane (FD-AM) and amnion sponge. Preserved grafts require to be sterilized by gamma irradiation. However, each step of the process could affect its biological properties. Even so, there
Heri Suroto, Deny M. Aryawan, Camilla A. Prakoeswa   +2 more
doaj   +2 more sources

Amnion membrane hydrogel and amnion membrane powder accelerate wound healing in a full thickness porcine skin wound model

Stem Cells Translational Medicine, 2020
There is a need for effective wound treatments that retain the bioactivity of a cellular treatment, but without the high costs and complexities associated with manufacturing, storing, and applying living biological products.
Sean V. Murphy, Aleksander Skardal, Ronald A. Nelson Jr., Khiry Sunnon, Tanya Reid, Cara Clouse, Nancy D. Kock, John Jackson, Shay Soker, Anthony Atala   +9 more
doaj   +2 more sources

C/EBPδ drives key endocrine signals in the human amnion at parturition

Clinical and Translational Medicine, 2021
Amnion‐derived prostaglandin E2 (PGE2) and cortisol are key to labor onset. Identification of a common transcription factor driving the expression of both cyclooxygenase‐2 (COX‐2) and 11β‐hydroxysteroid dehydrogenase 1 (11β‐HSD1), the key enzymes in ...
Jiang‐Wen Lu, Wang‐Sheng Wang, Qiong Zhou, Li‐Jun Ling, Hao Ying, Yun Sun, Leslie Myatt, Kang Sun   +7 more
doaj   +2 more sources

The development of the amnion in mice and other amniotes

Philosophical Transactions of the Royal Society B: Biological Sciences, 2022
The amnion is an extraembryonic tissue that evolutionarily allowed embryos of all amniotes to develop in a transient and local aquatic environment. Despite the importance of this tissue, very little is known about its formation and its molecular characteristics.
Susana M. Chuva de Sousa Lopes, Bernard A. J. Roelen, Kirstie A. Lawson, An Zwijsen   +3 more
openaire   +6 more sources

Effect of Acellular Amnion With Increased TGF-β and bFGF Levels on the Biological Behavior of Tenocytes

Frontiers in Bioengineering and Biotechnology, 2020
The human amniotic membrane has been a subject for clinical and basic research for nearly 100 years, but weak rejection has been reported. The purpose of this research is to remove the cellular components of the amnion for eliminating its immune-inducing
Rongli Sang, Yuanyuan Liu, Lingyu Kong, Ligang Qian, Chunjie Liu   +4 more
doaj   +2 more sources

Electrospun polycaprolactone (PCL)-amnion nanofibrous membrane prevents adhesions and promotes nerve repair in a rat model of sciatic nerve compression.

PLoS ONE, 2020
Adhesion and scarring after neural surgery are detrimental to nerve regeneration and functional recovery. Amniotic membranes have been used in tissue repair due to their immunogenicity and richness in cytokines.
Ruiyi Dong, Chunjie Liu, Siyu Tian, Jiangbo Bai, Kunlun Yu, Lei Liu, Dehu Tian   +6 more
doaj   +2 more sources

Injectable amnion hydrogel-mediated delivery of adipose-derived stem cells for osteoarthritis treatment

Proceedings of the National Academy of Sciences of the United States of America, 2022
Significance Osteoarthritis (OA) is a chronic disease affecting millions of people worldwide with no curative solution. In the present study, we developed a minimally invasive injectable system using amnion membrane (AM) from the human placenta as a ...
Maumita Bhattacharjee, J. L. Escobar Ivirico, H. Kan, Shiv Shah, T. Otsuka, Rosalie Bordett, Mohammed A Barajaa, Naveen Nagiah, Rishikesh Pandey, L. Nair, C. Laurencin   +10 more
semanticscholar   +1 more source

Amnion signals are essential for mesoderm formation in primates

Nature Communications, 2021
Embryonic development is largely conserved among mammals. However, certain genes show divergent functions. By generating a transcriptional atlas containing >30,000 cells from post-implantation non-human primate embryos, we uncover that ISL1, a gene with ...
Ran Yang, A. Goedel, Yu Kang, Chenyang Si, Chu Chu, Yi Zheng, Zhenzhen Chen, P. Gruber, Yao Xiao, Chikai Zhou, Nevin Witman, E. Eroglu, C. Leung, Yongchang Chen, Jianping Fu, W. Ji, F. Lanner, Yuyu Niu, K. Chien   +18 more
semanticscholar   +1 more source