Results 21 to 30 of about 44,340 (376)

Characteristics and Therapeutic Potential of Human Amnion-Derived Stem Cells

International Journal of Molecular Sciences, 2021
Stem cells including embryonic stem cells (ESCs), induced pluripotent stem cells (iPSCs) and adult stem cells (ASCs) are able to repair/replace damaged or degenerative tissues and improve functional recovery in experimental model and clinical trials ...
Quan-Wen Liu, Qi-Ming Huang, Han-You Wu, Guo-Si-Lang Zuo, Haorong Gu, Ke-Yu Deng, H. Xin   +6 more
semanticscholar   +1 more source

The Bradykinin System Contributes to the Regulation of Prostaglandin-Endoperoxide Synthase 2 Expression in Human Amnion Fibroblasts: Implications for Term and Preterm Birth

Frontiers in Endocrinology, 2022
BackgroundBradykinin (BK) and its biologically active metabolite des-Arg9 bradykinin (DABK) play a pivotal role in inflammation. Since chorioamnionitis is the leading cause of preterm birth and prostaglandin E2 (PGE2) derived from the amnion is key to ...
Xiao-tian Ni, Wang-sheng Wang, Wang-sheng Wang, Yun Liu, Yi-kai Lin, Yi-kai Lin, Fan Zhang, Fan Zhang, Wen-jia Lei, Wen-jia Lei, Li-jun Ling, Fan Pan, Fan Pan, Ya-nan Zhu, Ya-nan Zhu, Meng-die Li, Meng-die Li, Tao Duan, Ming Liu, Kang Sun, Kang Sun   +20 more
doaj   +1 more source

BMP-treated human embryonic stem cells transcriptionally resemble amnion cells in the monkey embryo

bioRxiv, 2021
Human embryonic stem cells (hESCs) possess an immense potential to generate clinically relevant cell types and unveil mechanisms underlying early human development.
Sapna Chhabra, Aryeh Warmflash
semanticscholar   +1 more source

Nuclear factor kappa B activation occurs in the amnion prior to labour onset and modulates the expression of numerous labour associated genes. [PDF]

PLoS ONE, 2012
BACKGROUND: Prior to the onset of human labour there is an increase in the synthesis of prostaglandins, cytokines and chemokines in the fetal membranes, particular the amnion.
Sheri Lim, David A MacIntyre, Yun S Lee, Shirin Khanjani, Vasso Terzidou, T G Teoh, Phillip R Bennett   +6 more
doaj   +1 more source

Reprogrammed iBlastoids contain amnion-like cells but not trophectoderm

bioRxiv, 2021
Two recent papers in Nature show that human blastocyst-like structures (or blastoids) can be generated from human pluripotent stem cells1 or through reprogramming of fibroblasts2, respectively.
Cheng-Yuan Zhao, Alvaro Plaza Reyes, J. P. Schell, Jere Weltner, Nicolás M. Ortega, Yi Zheng, K. Åsa, Björklund, Janet Rossant, Jianping Fu, S. Petropoulos, F. Lanner   +11 more
semanticscholar   +1 more source

Comparison of angiogenic, cytoprotective, and immunosuppressive properties of human amnion- and chorion-derived mesenchymal stem cells. [PDF]

PLoS ONE, 2014
Although mesenchymal stem cells (MSCs) can be obtained from the fetal membrane (FM), little information is available regarding biological differences in MSCs derived from different layers of the FM or their therapeutic potential.
Kenichi Yamahara, Kazuhiko Harada, Makiko Ohshima, Shin Ishikane, Shunsuke Ohnishi, Hidetoshi Tsuda, Kentaro Otani, Akihiko Taguchi, Toshihiro Soma, Hiroyasu Ogawa, Shinji Katsuragi, Jun Yoshimatsu, Mariko Harada-Shiba, Kenji Kangawa, Tomoaki Ikeda   +14 more
doaj   +1 more source

Electrospun Polycaprolactone (PCL)-Amnion Nanofibrous Membrane Promotes Nerve Regeneration and Prevents Fibrosis in a Rat Sciatic Nerve Transection Model

Frontiers in Surgery, 2022
Functional recovery after peripheral nerve injury repair is typically unsatisfactory. An anastomotically poor microenvironment and scarring at the repair site are important factors impeding nerve regeneration.
Jiangbo Bai, Chunjie Liu, Lingde Kong, Siyu Tian, Kunlun Yu, Dehu Tian   +5 more
doaj   +1 more source

Amnion and Chorion Allografts in Combination with Coronally Advanced Flap in the Treatment of Gingival Recession: A Clinical Study [PDF]

Journal of Clinical and Diagnostic Research, 2015
Background: Guided tissue regeneration (GTR) based root coverage using different allograft membranes has been utilized to correct gingival recession defects with promising results.
Sonali Chakraborthy, Savita Sambashivaiah, Rithesh Kulal, Shivaprasad Bilchodmath   +3 more
doaj   +1 more source

Reversible EMT and MET mediate amnion remodeling during pregnancy and labor

Science Signaling, 2020
Balanced EMT and MET maintain amnion integrity during pregnancy, and increased EMT is associated with labor. Remodeling the amnion During pregnancy, the amniotic membrane undergoes growth, repair, and remodeling processes that depend on epithelial-to ...
L. Richardson, Robert N. Taylor, R. Menon   +2 more
semanticscholar   +1 more source

Exosomal miR-135a derived from human amnion mesenchymal stem cells promotes cutaneous wound healing in rats and fibroblast migration by directly inhibiting LATS2 expression

Stem cell research & therapeutics, 2020
Wound healing is a complex pathophysiological process that involves a variety of cells and cytokines. In this study, we found that local injection of human amnion mesenchymal stem cells into wounds in rats could promote wound healing.
Shaoying Gao, Tao Chen, Y. Hao, Feifei Zhang, Xiu-jun Tang, Dali Wang, Zairong Wei, J. Qi   +7 more
semanticscholar   +1 more source