Results 81 to 90 of about 33,241 (310)

Isolation and characterization of mesenchymal stem cells from human amniotic membrane [PDF]

, 2011
[Abstract] Introduction: The human amniotic membrane is a highly abundant and readily available tissue that may be useful for regenerative medicine and cell therapy.
Blanco García, Francisco J, De-Toro, Javier, Díaz-Prado, Silvia, Fuentes Boquete, Isaac Manuel, Hermida Gómez, Tamara, Muíños-López, Emma, Rendal Vázquez, María Esther   +6 more
core   +2 more sources

Novel MYL1 Intron Variant With Expanded Phenotype

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Congenital myopathy‐14 (CMYO14) is an ultrarare autosomal recessive disorder caused by biallelic variants in MYL1, with only four patients reported to date. We describe what is likely the fifth reported patient, a neonate with severe hypotonia, respiratory insufficiency, and skeletal anomalies showing distinct histological changes of skeletal ...
Maria Barington, Marie Balslev‐Harder, Thomas Krag, Thomas van Overeem Hansen, Camilla Bernt Wulff, Ulrik Lausten‐Thomsen, Tina Duelund Hjortshøj, Elsebet Østergaard   +7 more
wiley   +1 more source

Periostin as a Biomarker of the Amniotic Membrane

Stem Cells International, 2012
Tracing the precise developmental origin of amnion and amnion-derived stem cells is still challenging and depends chiefly on analyzing powerful genetic model amniotes like mouse. Profound understanding of the fundamental differences in amnion development
Mariya P. Dobreva, Larissa Lhoest, Paulo N. G. Pereira, Lieve Umans, Susana M. Chuva de Sousa Lopes, An Zwijsen   +5 more
doaj   +1 more source

miRNA contributions to pediatric-onset multiple sclerosis inferred from GWAS. [PDF]

, 2019
ObjectiveOnset of multiple sclerosis (MS) occurs in childhood for approximately 5% of cases (pediatric MS, or ped-MS). Epigenetic influences are strongly implicated in MS pathogenesis in adults, including the contribution from microRNAs (miRNAs), small ...
Aaen, Gregory, Barcellos, Lisa F, Belman, Anita, Benson, Leslie, Caillier, Stacy, Candee, Meghan S, Casper, T Charles, Chitnis, Tanuja, Gorman, Mark, Graves, Jennifer S, Greenberg, Benjamin M, Harris, Yolanda, Hart, Janace, Kahn, Ilana, Krupp, Lauren, Lotze, Timothy, Mar, Soe, Ness, Jayne, Quach, Diana, Quach, Hong, Rhead, Brooke, Rodriguez, Moses, Rose, John, Rubin, Jennifer, Schaefer, Catherine, Schreiner, Teri, Shao, Xiaorong, Tillema, Jan M, US Network of Pediatric MS Centers, Waldman, Amy T, Waubant, Emmanuelle, Weinstock-Guttman, Bianca   +31 more
core   +2 more sources

Prenatal Evaluation of RNU4‐2 Variants in Fetuses With Central Nervous System Anomalies

American Journal of Medical Genetics Part C: Seminars in Medical Genetics, EarlyView.
ABSTRACT Fetal central nervous system (CNS) anomalies are among the most common congenital malformations, yet the overall prenatal diagnostic yield of current genetic testing remains below 40%. Variants in RNU4‐2, a non‐coding gene encoding the U4 small nuclear RNA (snRNA), have recently been linked to a novel highly recurrent dominant ...
Yiyao Chen, Li Gao, Xu Han, Yunyun Cao, Lanlan Zhang, Yi Wu, Xinrong Zhao, Wenjing Hu, Ruiyu Ma, Renyi Hua, Niu Li, Yanlin Wang, Jian Wang, Shuyuan Li   +13 more
wiley   +1 more source

Placental-mediated increased cytokine response to lipopolysaccharides: a potential mechanism for enhanced inflammation susceptibility of the preterm fetus. [PDF]

, 2012
BackgroundCerebral palsy is a nonprogressive motor impairment syndrome that has no effective cure. The etiology of most cases of cerebral palsy remains unknown; however, recent epidemiologic data have demonstrated an association between fetal neurologic ...
Belkacemi, Louiza, Beloosesky, Ron, Boles, Julie L, Desai, Mina, Ross, Michael G   +4 more
core   +1 more source

A perspective from the Mesozoic: Evolutionary changes of the mammalian skull and their influence on feeding efficiency and high‐frequency hearing

The Anatomical Record, EarlyView.
Abstract The complex evolutionary history behind modern mammalian chewing performance and hearing function is a result of several changes in the entire skeletomuscular system of the skull and lower jaw. Lately, exciting multifunctional 3D analytical methods and kinematic simulations of feeding functions in both modern and fossil mammals and their ...
Julia A. Schultz
wiley   +1 more source

Comparative Characterization of Cultured Human Term Amnion Epithelial and Mesenchymal Stromal Cells for Application in Cell Therapy

Cell Transplantation, 2008
Emerging evidence suggests human amnion tissue as a valuable source of two distinct types of pluripotent cells, amnion epithelial cells (hAECs) and mesenchymal stromal cells (hAMSCs), for applications in cell replacement therapy.
Grozdana Bilic, Steffen M. Zeisberger, Ajit S. Mallik, Roland Zimmermann, Andreas H. Zisch   +4 more
doaj   +1 more source

Amnion as a surrogate tissue reporter of the effects of maternal preeclampsia on the fetus [PDF]

, 2016
We described the study design, detailed analytical methods, and verification results in the supporting information file.
Brent R. Calder, David M. Reynolds, Francine Hughes Einstein, Hye J. Heo, John M. Greally, Masako Suzuki, Nicole E. Patterson, Ryo Maekawa, Sandra E. Reznik   +8 more
core   +2 more sources

Trabecular bone ontogeny of the human talus

The Anatomical Record, EarlyView.
Abstract Studies of trabecular ontogeny may provide insight into the factors that drive healthy bone development. There is a growing understanding of how the juvenile skeleton responds to these influences; however, gaps in our knowledge remain. This study aims to identify ontogenetic trabecular patterns and regional changes during development within ...
Rebecca A. G. Reid, Catriona Davies, Craig Cunningham   +2 more
wiley   +1 more source