Results 41 to 50 of about 104,154 (143)

Cytochrome P450 monooxygenase of Acanthamoeba castellanii participates in resistance to polyhexamethylene biguanide treatment

Parasite, 2021
Acanthamoeba spp. are free-living parasites that can cause severe infections such as granulomatous amoebic encephalitis (GAE) and amoebic keratitis (AK). Polyhexamethylene biguanide (PHMB) is a topical application for AK treatment.
Huang Jian-Ming, Ko Pin-Ju, Huang Chao-Li, Wen Po-Wei, Chen Chun-Hsien, Shih Min-Hsiu, Lin Wei-Chen, Huang Fu-Chin   +7 more
doaj   +1 more source

Discovery of repurposing drug candidates for the treatment of diseases caused by pathogenic free-living amoebae.

PLoS Neglected Tropical Diseases, 2020
Diseases caused by pathogenic free-living amoebae include primary amoebic meningoencephalitis (Naegleria fowleri), granulomatous amoebic encephalitis (Acanthamoeba spp.), Acanthamoeba keratitis, and Balamuthia amoebic encephalitis (Balamuthia ...
Christopher A Rice, Beatrice L Colon, Emily Chen, Mitchell V Hull, Dennis E Kyle   +4 more
doaj   +1 more source

Granulomatous amoebic encephalitis in an immunocompetent young female: A rare case with microbiological confirmation and survival

Indian Journal of Case Reports
Granulomatous amoebic encephalitis (GAE) is an uncommon but life-threatening central nervous system infection caused by Acanthamoeba species. It predominantly affects immunocompromised individuals, although cases in immunocompetent hosts are increasingly
Jyoti Mishra, Dipankar Paul, Chitrita Chatterjee, Raja Ray   +3 more
semanticscholar   +1 more source

Olfactory Tuft Cells Are Critical to Basal Inflammation, Innate Immune Response to Viral Infection, and Modulation of Quiescent Stem Cell Activation, Proliferation and Differentiation

Cell Proliferation, EarlyView.
Olfactory tuft cells communicate with other mucosal cells in maintaining olfactory epithelial immunity and sensory function. Disruption of tuft cell signalling pathways causes a skewed immune response, leading to heightened inflammation and increased activation of the quiescent stem cells, which are further exacerbated by viral infection.
Sai‐Sai Zhang, Haiyan Wang, Yi‐Sen Yang, Yi‐Hong Li, Defu Yu, Yushi Yao, Ruhong Zhou, Liquan Huang   +7 more
wiley   +1 more source

A Novel Balamuthia Lineage Causing Fatal Granulomatous Amoebic Encephalitis in an Immunocompetent Infant.

International Journal of Infectious Diseases
OBJECTIVES To characterize a genetically distinct Balamuthia lineage causing fatal granulomatous amoebic encephalitis (GAE) in a 10-month-old infant and highlight diagnostic challenges compounded by SARS-COV-2 infection comorbidity. METHODS Case report
Zhong-Qiu Teng, Lin-Lin Li, Tianming Che, Jun-Rong Liang, Xing-Feng Yao, Na Zhao, Fengmao Zhao, Hailang Sun, Li-Juan Wang, Quan Wang, Gang Liu, Tian Qin   +11 more
semanticscholar   +1 more source

Mechanisms of parasite‐mediated disruption of brain vessels

FEBS Letters, Volume 600, Issue 5, Page 591-611, March 2026.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira, Sílvia Arroz‐Madeira, Cláudio A. Franco, Sara Silva Pereira   +3 more
wiley   +1 more source

Pyogenic Hepatic Abscess as a Complication of Appendicitis: A Case Report

Clinical Case Reports, Volume 14, Issue 3, March 2026.
Pyogenic liver abscess management. ABSTRACT Pyogenic liver abscess is a rare and under‐recognized complication of gangrenous or perforated appendicitis in children. Management typically requires a combination of antibiotic therapy and abscess drainage. Although uncommon in the pediatric population, pyogenic liver abscess is more frequently observed in ...
Mohammad AshrafAzimi, Abbas Abdollahi, Mohammad karimi, Homa Jajarmi, Ali Mehri   +4 more
wiley   +1 more source

Balamuthia mandrillaris amoebic encephalitis clinically mimicking myasthenia gravis exacerbation: a diagnostic challenge

Access Microbiology
Balamuthia mandrillaris is a rare cause of granulomatous amoebic encephalitis (GAE) with a high mortality rate. Here, we describe the diagnostic challenges in a 70-year-old immunocompromised man with myasthenia gravis (MG).
Zohre Sadeghian, Richard A. Prayson, F. Abuzeid, Alma Reyes-Trocchia, Amir Behdad   +4 more
semanticscholar   +1 more source

Trouble in the Tank: A Case Report of Fatal Scuticociliate Encephalitis in a Whitetip Reef Shark (Triaenodon obesus)

Journal of Fish Diseases, Volume 49, Issue 3, March 2026.
Abstract This case report presents a recent case of scuticociliatosis in a whitetip reef shark (Triaenodon obesus), housed at a zoo (Haus des Meeres Aqua Terra Zoo, Vienna, Austria). Clinical signs such as uncoordinated swimming and body tilt were observed prior to death.
Hella Schwegler, Jeff Schreiner, Maria Prüllage, Karoline Lipnik, Astrid S. Holzer, Eva Lewisch   +5 more
wiley   +1 more source

Editorial for the Special Issue “Advances in Acanthamoeba”

Microorganisms
Some free-living amoebae can behave as opportunistic parasites, causing rare but dangerous diseases in humans and animals, primarily amoebic keratitis, with loss of vision, and encephalitis, which is almost always fatal [...]
Daniele Corsaro
doaj   +1 more source